NCT06397261

Brief Summary

This study aims to asses if the application of the larynGuide™, an assistive software running on a video-laryngoscope platform guiding laryngoscopy and intubation advise correctly and reliably on the position of the tracheal tube after an intubation attempt.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
110

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jun 2024

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 29, 2024

Completed
3 days until next milestone

First Posted

Study publicly available on registry

May 2, 2024

Completed
1 month until next milestone

Study Start

First participant enrolled

June 3, 2024

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 30, 2025

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

May 8, 2025

Completed
Last Updated

May 14, 2025

Status Verified

May 1, 2024

Enrollment Period

10 months

First QC Date

April 29, 2024

Last Update Submit

May 9, 2025

Conditions

Keywords

Artificial IntelligenceTracheal video intubationlarynGuide

Outcome Measures

Primary Outcomes (1)

  • Rate of correct assessment given by larynGuide™

    Correctness of the advice measured by accuracy of the LarynGuide™, a software for artificial intelligence assisted tracheal intubation (aiEndoscopic, Zürich, Switzerland) on tube position given at the end of an intubation attempt

    5 minutes

Secondary Outcomes (7)

  • Overall success rate

    5 minutes

  • first-attempt success rate

    10 minutes

  • Number of attempts

    5 minutes

  • Number of incidents of technical problems of larynGuide™

    10 minutes

  • Percentage of glottic opening

    2 minutes

  • +2 more secondary outcomes

Study Arms (1)

adult patients undergoing elective surgery

adult patients undergoing elective surgery requiring tracheal intubation

Device: LarynGuide

Interventions

Artificial Intelligence assisted tracheal video intubation

adult patients undergoing elective surgery

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

german speaking adult patients classified ASA I, II or III undergoing surgery (except intracranial surgery) in general anaesthesia with tracheal intubation without contraindication for intubation with C-mac or indication for impossible mask ventilation and high aspiration risk with given informend consent.

You may qualify if:

  • male or female patients ≥18 years
  • ASA class I to III
  • undergoing elective surgery in general anesthesia with tracheal intubation

You may not qualify if:

  • Contraindication for intubation with C-MAC video laryngoscope (Karl Storz, Tuttlingen, Germany) with a Macintosh nr 3 or 4 blade
  • Patients \< 18 years
  • No proper trained personnel for the device at the study site
  • Expected impossible mask ventilation.
  • High risk of aspiration (requiring rapid sequence induction intubation)
  • Intracranial surgery
  • Limited knowledge of German language or refusing informed consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Inselspital

Bern, Canton of Bern, 3010, Switzerland

Location

Study Officials

  • Thomas Riva, Prof.

    Bern Univerisity Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Prof. Dr. med. Thomas Riva

Study Record Dates

First Submitted

April 29, 2024

First Posted

May 2, 2024

Study Start

June 3, 2024

Primary Completion

March 30, 2025

Study Completion

May 8, 2025

Last Updated

May 14, 2025

Record last verified: 2024-05

Locations