Anesthetic Management for TA-BSM in HOCM

NCT06397092 | Completed DMC

• 1 other identifier: TongjiHospital-Anes QQ03
• Study Type: observational
• Target: 120
• Locations: 1 country
• Sites: 1

Brief Summary

To retrospectively analyze the preoperative, intraoperative and postoperative anesthesia management of patients with hypertrophic cardiomyopathy undergoing TA-BSM in the investigators' hospital, and to provide clinical basis for the development of reasonable and standardized perioperative anesthesia program for these patients.

Conditions

Anesthesia; Transapical Beating-heart Septal Myectomy; Hypertrophic Cardiomyopathy

Outcome Measures

Primary Outcomes (10)

• Perioperative information 1

  Heart reat

  During surgery, when use isoproterenol to provocate

• Perioperative information 2

  Systolic arterial blood pressure

  During surgery, when use isoproterenol to provocate

• Perioperative information 3

  Diastolic arterial blood pressure

  During surgery, when use isoproterenol to provocate

• Perioperative information 4

  Mean arterial blood pressure

  During surgery, when use isoproterenol to provocate

• Perioperative information 5

  The type of tracheal tube

  Immediately after the surgery

• Perioperative information 6

  The usage of anaesthetic drugs

  Immediately after the surgery

• Perioperative information 7

  The usage of cardiovascular drugs

  Immediately after the surgery

• Perioperative information 8

  Intraoperative infusion volume

  Immediately after the surgery

• Perioperative information 9

  Blood transfusion volume

  Immediately after the surgery

• Perioperative information 10

  Blood loss

  Immediately after the surgery

Secondary Outcomes (8)

• Postoperative information 1

  Postoperative in 30 days

• Postoperative information 2

  Postoperative in 30 days

• Postoperative information 3

  Postoperative in 30 days

• Postoperative information 4

  Postoperative in 30 days

• Laboratory tests information 1

  7 days before surgery and 3 days after surgery

Study Arms (1)

TA-BSM

The hypertrophic cardiomyopathy patients received TA-BSM

Procedure: transapical beating-heart septal myectomy

Interventions

transapical beating-heart septal myectomy PROCEDURE

The patients with hypertrophic cardiomyopathy undergoing TA-BSM

TA-BSM

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The information of all patients with hypertrophic cardiomyopathy undergoing TA-BSM in our hospital from April 2022 to January 2023 was extracted and screened according to the inclusion criteria and exclusion criteria

You may qualify if:

• Patients with hypertrophic cardiomyopathy
• American Society of Anesthesiologists (ASA) physical status classification I-III
• Undergoing TA-BSM

You may not qualify if:

• Cardiopulmonary bypass was used to assist the surgery.

Sponsors & Collaborators

• Tongji Hospital: lead

Study Sites (1)

Tongji Hospital, Tongji Medical College, Huazhong Science and Technology University

Wuhan, Hubei, 430030, China

Location

MeSH Terms

Conditions

Cardiomyopathy, Hypertrophic

Condition Hierarchy (Ancestors)

Cardiomyopathies; Heart Diseases; Cardiovascular Diseases; Aortic Stenosis, Subvalvular; Aortic Valve Stenosis; Aortic Valve Disease; Heart Valve Diseases

Study Officials

• Wenlong Yao

  Tongji Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate professor and deputy chief physician

Study Record Dates

• First Submitted: April 7, 2024
• First Posted: May 2, 2024
• Study Start: April 1, 2022
• Primary Completion: January 31, 2023
• Study Completion: March 31, 2024
• Last Updated: May 2, 2024

Record last verified: 2024-05

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)