Hypertrophic Cardiomyopathy
157
26
36
72
Key Insights
Highlights
Success Rate
91% trial completion (above average)
Published Results
12 trials with published results (8%)
Research Maturity
72 completed trials (46% of total)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 50/100
4.5%
7 terminated out of 157 trials
91.1%
+4.6% vs benchmark
8%
12 trials in Phase 3/4
17%
12 of 72 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.6%
Based on 72 completed trials
Clinical Trials (157)
Cardiovascular Multimodality Imaging Study
A Study of EDG-7500 in Adults With Hypertrophic Cardiomyopathy (CIRRUS-HCM)
Pediatric Cardiomyopathy Mutation Analysis
Healthy-related Quality of Life and Physical Activity of Children With Cardiac Malformations
A Study to Assess the Real-World Effectiveness of Mavacamten in Adult Patients With Obstructive Hypertrophic Cardiomyopathy in China
A Retrospective Cohort Study of Mavacamten Patient Support Program in Canada
Assessment of the Relations Between Endothelial and Venous Dysfunctions and Left Ventricular Obstruction in Genetic Hypertrophic Cardiomyopathies
Hypertrophic Cardiomyopathy Symptom Release by BX1514M
A Study of Artificial Intelligence ECG With ECG Devices to Detect Hypertrophic Cardiomyopathy Distinct From Athlete's
Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCM
Empagliflozin in Hypertrophic Cardiomyopathy
A Long-Term Safety Extension Study of Mavacamten in Adults Who Have Completed MAVERICK-HCM or EXPLORER-HCM
Pilot Study of Hypertrophic Cardiomyopathy & Implantable Cardioverter Defibrillator Assessment: (Subcutaneous vs Transvenous)
Effect of Personalized Accelerated Pacing in Symptomatic Patients With Non-Obstructive Hypertrophic Cardiomyopathy
A Prospective Incident Study of Arrhythmias in Hypertrophic Cardiomyopathy
Institutional Registry of Rare Diseases
NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Early Feasibility Study
Austrian Hypertrophic Cardiomyopathy Registry
Exercise Intolerance in Non-obstructive Hypertrophic Cardiomyopathy
A Trial of HRS-1893 in Healthy Volunteers