Coconut Oil in Treatment of Periodontitis
Efficacy of Locally Delivered Coconut Oil in Management of Stage II and III Grade B Periodontitis. A Randomized Controlled Clinical Trial
1 other identifier
interventional
34
1 country
1
Brief Summary
Virgin Coconut Oil (VCO) is a vegetable oil extracted from coconut fleshcontains unsaturated fatty acids in the form of oleic acid and linoleic acid and flavonoids which function as anti-inflammatory. Periodontitis is an inflammatory disease of the periodontal tissues with a high prevalence worldwide. The main etiology of plaque periodontitis is biofilm containing colonies of pathogenic microorganisms. The aim of the study is to evaluate and compare the effect of scaling and root debridement alone versus the use of topically applied coconut oil as adjunctive to scaling and root debridement in treatment of Stage II and III Grade B periodontitis.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for phase_1
Started Feb 2022
Typical duration for phase_1
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 15, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 16, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
February 9, 2024
CompletedFirst Submitted
Initial submission to the registry
April 19, 2024
CompletedFirst Posted
Study publicly available on registry
April 25, 2024
CompletedApril 25, 2024
April 1, 2024
1.9 years
April 19, 2024
April 24, 2024
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
clinical parameters
clinical attachment loss
3 months
clinical parameters
Probing depth
3 months
Secondary Outcomes (1)
Biological parameters
3 months
Study Arms (2)
interventional
ACTIVE COMPARATORcoconut oil as topical application as adjunctive to scaling and root debridement
control
ACTIVE COMPARATORscaling and root debridement
Interventions
Eligibility Criteria
You may qualify if:
- patients age group \>35 years without ant systemic disease
- Willing to take part in the study. Patients with more than 16 natural teeth and have test teeth with both mesial and distal neighboring teeth with periodontitis with clinical attachment loss \>3 mm and radiographic percentage of bone loss/age ranged between 0.25 to 1.
- Patients with no history of allergies to coconut
You may not qualify if:
- smokers
- pregnant
- lactating women
- Teeth with both endodontic-periodontal lesion.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Faculty of dentistry at MUST
Giza, 02, Egypt
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- phase 1
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- CARE PROVIDER, OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- lecturer of oral medicine, periodontology and oral diagnosis at Misr University for science and technology
Study Record Dates
First Submitted
April 19, 2024
First Posted
April 25, 2024
Study Start
February 15, 2022
Primary Completion
January 16, 2024
Study Completion
February 9, 2024
Last Updated
April 25, 2024
Record last verified: 2024-04
Data Sharing
- IPD Sharing
- Will not share