The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)
A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Event-Driven Study to Investigate the Effect of Retatrutide on the Incidence of Major Adverse Cardiovascular Events and Major Adverse Kidney Events in Participants With Body Mass Index ≥27 kg/m2 and Atherosclerotic Cardiovascular Disease and/or Chronic Kidney Disease
3 other identifiers
interventional
10,000
26 countries
729
Brief Summary
The main purpose of this study is to determine if retatrutide can significantly lower the incidence of serious heart-related complications or prevent the worsening of kidney function. The trial will enroll adults with body mass index 27 kg/m\^2 or higher and Atherosclerotic Cardiovascular Disease and/or chronic kidney disease. The study will last for about 5 years. Participants will have up to 27 clinic visits with the study doctor.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for phase_3
Started Apr 2024
Longer than P75 for phase_3
729 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
April 22, 2024
CompletedFirst Posted
Study publicly available on registry
April 25, 2024
CompletedStudy Start
First participant enrolled
April 30, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 1, 2029
ExpectedStudy Completion
Last participant's last visit for all outcomes
February 1, 2029
April 20, 2026
April 1, 2026
4.8 years
April 22, 2024
April 17, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Time to First Occurrence of Composite Endpoints
A composite endpoint includes nonfatal myocardial infarction (MI), nonfatal stroke, cardiovascular (CV) death, or hospitalization or urgent visit due to heart failure (HF).
Randomization up to Study Completion (Approximate 248 Weeks)
Time to First Occurrence of Composite Endpoint of End Stage Kidney Disease (ESKD), ≥ 40% Sustained Decline in Estimated Glomerular Filtration Rate (eGFR), CV Death or Renal Death
ESKD is defined as the following individual components: persistent eGFR \<15 mL/min/1.73 m\^2 confirmed by 2 measurements at least 4 weeks apart at the central laboratory, initiation of dialysis for at least 28 days, receiving a kidney transplant. Sustained decline in eGFR (≥40%) will be confirmed by a repeated measure at least 4 weeks after the first result.
Randomization up to Study Completion (Approximate 248 Weeks)
Secondary Outcomes (5)
Time to First Occurrence of Composite Endpoint of Major Cardiovascular Events (MACE-3)
Randomization up to Study Completion (Approximate 248 Weeks)
Time to First Occurrence of Composite Endpoint of CV death, or hospitalization or urgent visit due to HF
Randomization up to Study Completion (Approximate 248 Weeks)
Time to Occurrence of All-Cause Death
Randomization up to Study Completion (Approximate 248 Weeks)
Time to First Occurrence of composite endpoint of ≥ 40% Sustained Decline in eGFR, End-Stage Renal Disease (ESRD), or Renal Death
Randomization up to Study Completion (Approximate 248 Weeks)
Percentage change from Baseline in Albuminuria urinary albumin/creatinine ratio (UACR) in Participants with UACR ≥30 mg/g (0.03 mg/mg) at baseline
Randomization up to Study Completion (Approximate 248 Weeks)
Study Arms (2)
Retatrutide
EXPERIMENTALParticipants will receive escalated doses of retatrutide administered subcutaneously (SC) up to a maximum tolerated dose.
Placebo
PLACEBO COMPARATORParticipants will receive matching placebo administered SC.
Interventions
Eligibility Criteria
You may qualify if:
- Participants may be without type 2 diabetes (T2D), or with T2D if their hemoglobin A1c (HbA1c) is 10% or lower
- Participants have established atherosclerotic cardiovascular disease (ASCVD) and/or chronic kidney disease (CKD), as evidenced at least one of the following:
- Coronary artery disease
- Cerebrovascular disease
- Peripheral arterial disease
- Chronic kidney disease defined as:
- eGFR \<45 millilitres/minute/1.73 meter squared (mL/min/1.73m\^2) and UACR \>30 milligram/gram (mg/g) (0.030 mg/mg)
- eGFR \<60 mL/min/1.73 m\^2 and UACR \>100 mg/g (0.100 mg/mg), or
- eGFR \<75 mL/min/1.73 m\^2 and UACR \>300 mg/g (0.300 mg/mg) (eGFR is calculated by central lab based on Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) creatinine-cystatin c equation as determined by central lab)
- A Body Mass Index of ≥27.0 kilograms per meter squared (kg/m\^2)
You may not qualify if:
- Diabetes related:
- Participants have Type 1 Diabetes or any history of diabetic ketoacidosis
- CV related:
- Participants have any of the following cardiovascular conditions ≤ 90 days prior to randomization:
- Myocardial infarction
- Acute coronary syndrome
- Stroke, or
- Coronary, peripheral, or carotid artery arterial revascularization procedure.
- Have acute decompensated heart failure requiring hospitalization.
- Have New York Heart Association (NYHA) Classification Class IV heart failure at screening
- Kidney related:
- Participants have an eGFR \<20 mL/min/1.73 m\^2 at screening
- Have UACR \>5000 mg/g (5.000 mg/mg) at screening
- Have received any form of dialysis ≤ 90 days from the date of randomization
- Have either undergone a kidney transplant or have a transplant procedure scheduled
- +5 more criteria
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (745)
Alabama Kidney Research
Alabaster, Alabama, 35007, United States
Central Research Associates
Birmingham, Alabama, 35205, United States
Alliance for Multispecialty Research, LLC
Daphne, Alabama, 36526, United States
Nephrology Consultants
Huntsville, Alabama, 35805, United States
Alliance for Multispecialty Research, LLC
Mobile, Alabama, 36608, United States
Prime Medical Group, LLC dba Gilbert Center for Family Medicine, LLC
Gilbert, Arizona, 85296, United States
Sun City Clinical Research
Glendale, Arizona, 85304, United States
Arizona Kidney Disease & Hypertension Center (AKDHC) - Thunderbird
Glendale, Arizona, 85306, United States
Helios Clinical Research - SAZ-PDV-026
Paradise Valley, Arizona, 85253, United States
Banner University Medical Center Phoenix
Phoenix, Arizona, 85006, United States
Phoenix Clinical LLC
Phoenix, Arizona, 85014, United States
Elite Clinical Studies, LLC
Phoenix, Arizona, 85018, United States
Absolute Clinical Research
Phoenix, Arizona, 85051, United States
Scottsdale Clinical Trials
Scottsdale, Arizona, 85260, United States
Clinical Research Institute of Arizona (CRI) - Sun City West
Sun City West, Arizona, 85375, United States
Synexus Clinical Research US, Inc./Orange Grove Family Practice
Tucson, Arizona, 85741, United States
Cardiology and Medicine Clinic
Little Rock, Arkansas, 72204, United States
Kidney & Hypertension Center - Apple Valley
Apple Valley, California, 92307, United States
Invivo - Bakersfield
Bakersfield, California, 93309, United States
American Institute of Research
Beverly Hills, California, 90211, United States
Hope Clinical Research, Inc.
Canoga Park, California, 91303, United States
Valley Clinical Trials, Inc.
Covina, California, 91723, United States
North Coast Cardiology
Encinitas, California, 92024, United States
Neighborhood Healthcare Institute of Health
Escondido, California, 92025, United States
HB Clinical Trials - Fountain Valley
Fountain Valley, California, 92708, United States
Care Access - Huntington Beach
Huntington Beach, California, 92648, United States
Irvine Clinical Research
Irvine, California, 92614, United States
Scripps Whittier Diabetes Institute
La Jolla, California, 92037, United States
Long Beach Research Institute
Long Beach, California, 90805, United States
Ark Clinical Research
Long Beach, California, 90815, United States
North America Research Institute
Lynwood, California, 90262, United States
Valley Clinical Trials, Inc.
Northridge, California, 91325, United States
Desert Oasis Healthcare Medical Group
Palm Springs, California, 92262, United States
California Liver Research Institute
Pasadena, California, 91105, United States
Western University of Health Sciences
Pomona, California, 91766, United States
California Kidney Specialists
San Dimas, California, 91773, United States
Southern California Clinical Research
Santa Ana, California, 92701, United States
Care Access - Santa Clarita
Santa Clarita, California, 91321, United States
Encompass Clinical Research
Spring Valley, California, 91978, United States
Valiance Clinical Research
Tarzana, California, 91356, United States
Care Access - Thousand Oaks
Thousand Oaks, California, 91360, United States
Med Partners, Inc. dba Premiere Medical Center of Burbank, Inc.
Toluca Lake, California, 91602, United States
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Torrance, California, 90502, United States
UCLA South Bay Endocrinology
Torrance, California, 90505, United States
InvivoCure
Van Nuys, California, 91405, United States
National Institute of Clinical Research (NICR) - High Desert
Victorville, California, 92392, United States
Synexus Clinical Research US, Inc.
Vista, California, 92083, United States
Millennium Clinical Trials
Westlake Village, California, 91361, United States
Western Nephrology
Arvada, Colorado, 80002, United States
University of Colorado Anschutz Medical Campus
Aurora, Colorado, 80045, United States
Cardiology Associates of Fairfield County, P.C.
Stamford, Connecticut, 06905, United States
Chase Medical Research, LLC
Waterbury, Connecticut, 06708, United States
Excel Medical Clinical Trials
Boca Raton, Florida, 33434, United States
American Research Institute
Cutler Bay, Florida, 33157, United States
Fleming Island Center for Clinical Research
Fleming Island, Florida, 32003, United States
Jellinger and Lerman, MD PA dba The Center for Diabetes and Endocrine Care
Fort Lauderdale, Florida, 33312, United States
Florida Kidney Physicians - Fort Lauderdale
Fort Lauderdale, Florida, 33316, United States
East Coast Institute for Research, LLC
Jacksonville, Florida, 32216, United States
Lakeview Institute of Clinical Research
Leesburg, Florida, 34748, United States
Flourish Research - Miami, LLC
Miami, Florida, 33135, United States
New Age Medical Research Corporation
Miami, Florida, 33186, United States
Onhealth Research Center
Miami, Florida, 33186, United States
Inpatient Research Clinic
Miami Lakes, Florida, 33014, United States
CTR Oakwater, LLC
Orlando, Florida, 32806, United States
Omega Research Orlando
Orlando, Florida, 32808, United States
Florida Kidney Physicians, LLC
Port Charlotte, Florida, 33952, United States
Florida Kidney Physicians - Tampa
Riverview, Florida, 33578, United States
Cardiovascular Center of Sarasota
Sarasota, Florida, 34239, United States
Care Access - Tamarac
Tamarac, Florida, 33321, United States
MOORE Clinical Research, Inc. d/b/a TrueBlue Clinical Research
Tampa, Florida, 33607, United States
Care Access - Tampa
Tampa, Florida, 33625, United States
American Clinical Trials - Acworth
Acworth, Georgia, 30101, United States
Atlanta Diabetes Associates
Atlanta, Georgia, 30318, United States
Emory University School of Medicine
Atlanta, Georgia, 30322, United States
Fides Clinical Research
Atlanta, Georgia, 30342, United States
Southeastern Clinical Research Institute
Augusta, Georgia, 30904, United States
American Clinical Trials - Douglasville
Douglasville, Georgia, 30134, United States
Center for Advanced Research & Education
Gainesville, Georgia, 30501, United States
The Jones Center Clinical Research
Macon, Georgia, 31210, United States
North Georgia Clinical Research
Woodstock, Georgia, 30189, United States
Great Lakes Clinical Trials - Ravenswood
Chicago, Illinois, 60640, United States
Clinical Investigation Specialists
Gurnee, Illinois, 60031, United States
Nephrology Associates of Northern Illinois and Indiana (NANI) - Hinsdale
Hinsdale, Illinois, 60521, United States
Accellacare - DuPage
Lombard, Illinois, 60148, United States
Alliance for Multispecialty Research, LLC
Niles, Illinois, 60714, United States
Rockford Nephrology Associates
Rockford, Illinois, 61107, United States
Central Illinois Diabetes and Clinical Research a Division of Prairie Education and Research Cooperative
Springfield, Illinois, 62711, United States
Qualmedica Research, LLC
Evansville, Indiana, 47715, United States
Nephrology Associates of Northern Illinois and Indiana (NANI) - Fort Wayne
Fort Wayne, Indiana, 46804, United States
Indiana University Health Methodist Hospital
Indianapolis, Indiana, 46202, United States
Nephrology Associates of Northern Illinois and Indiana - IKS - Indianapolis South
Indianapolis, Indiana, 46227, United States
Care Access - South Indianapolis
Indianapolis, Indiana, 46254, United States
Reid Physician Associates
Richmond, Indiana, 47374, United States
Iowa Diabetes and Endocrinology Research Center
West Des Moines, Iowa, 50266, United States
The University of Kansas - Clinical Research Center
Fairway, Kansas, 66205, United States
Alliance for Multispecialty Research, LLC
Newton, Kansas, 67114, United States
Cotton O'Neil Clinical Research Center
Topeka, Kansas, 66606, United States
Cotton O'Neil Diabetes & Endocrinology
Topeka, Kansas, 66606, United States
Qualmedica Research
Bowling Green, Kentucky, 42101, United States
Alliance for Multispecialty Research, LLC
Lexington, Kentucky, 40509, United States
L-MARC Research Center
Louisville, Kentucky, 40213, United States
Care Access - Lake Charles
Lake Charles, Louisiana, 70601, United States
IMA Clinical Research Monroe - Armand
Monroe, Louisiana, 71201, United States
Alliance for Multispecialty Research, LLC
New Orleans, Louisiana, 70119, United States
Sinai Hospital Of Baltimore
Baltimore, Maryland, 21209, United States
Care Access - Baltimore
Baltimore, Maryland, 21213, United States
Ascension Saint Agnes Heart Care
Baltimore, Maryland, 21229, United States
MedStar Good Samaritan Hospital
Baltimore, Maryland, 21239, United States
Jadestone Clinical Research
Beltsville, Maryland, 20705, United States
Anderson Medical Research
Ft. Washington, Maryland, 20744, United States
MedStar Health Research Institute (MedStar Physician Based Research Network)
Hyattsville, Maryland, 20782, United States
NECCR PrimaCare Research
Fall River, Massachusetts, 02721, United States
Care Access - Quincy
Quincy, Massachusetts, 02169, United States
Revival Research Institute, LLC
Dearborn, Michigan, 48126, United States
Elixia MKC, LLC
Pontiac, Michigan, 48341, United States
Lake Michigan Nephrology
Saint Joseph, Michigan, 49085, United States
Great Lakes Research Institute
Southfield, Michigan, 48075, United States
Arcturus Healthcare , PLC, Troy Internal Medicine Research Division
Troy, Michigan, 48098, United States
StudyMetrix Research
City of Saint Peters, Missouri, 63303, United States
Alliance for Multispecialty Research, LLC
Kansas City, Missouri, 64114, United States
Clinvest Headlands Llc
Springfield, Missouri, 65807, United States
Mercury Street Medical Group, PLLC
Butte, Montana, 59701, United States
Boeson Research MSO
Missoula, Montana, 59804, United States
Henderson Clinical Trials
Henderson, Nevada, 89052, United States
DaVita Clinical Research - Las Vegas
Las Vegas, Nevada, 89107, United States
Excel Clinical Research, LLC
Las Vegas, Nevada, 89109, United States
Alliance for Multispecialty Research, LLC
Las Vegas, Nevada, 89119, United States
Advanced Biomedical Research of America - South Eastern Avenue
Las Vegas, Nevada, 89123, United States
Vector Clinical Trials
Las Vegas, Nevada, 89128, United States
Albany Medical College, Division of Community Endocrinology
Albany, New York, 12203, United States
Capital Cardiology Associates
Albany, New York, 12211, United States
Westchester Medical Center Advanced Physicians Service
Kingston, New York, 12401, United States
St. Francis Hospital & Heart Center
New Hyde Park, New York, 11576, United States
NYU Langone Health
New York, New York, 10016, United States
Icahn School of Medicine at Mount Sinai
New York, New York, 10029, United States
Saratoga Clinical Research
Saratoga Springs, New York, 12866, United States
Care Access - Fayetteville
Fayetteville, North Carolina, 28314, United States
Medication Management
Greensboro, North Carolina, 27405, United States
Physician's East Endocrinology
Greenville, North Carolina, 27834, United States
IMA Clinical Research - Lenoir
Lenoir, North Carolina, 28645, United States
West Clinical Research
Morehead City, North Carolina, 28557, United States
Accellacare - Raleigh
Raleigh, North Carolina, 27609, United States
Accellacare - Wilmington - 1917 Tradd Court
Wilmington, North Carolina, 28401, United States
Advanced Medical Research
Maumee, Ohio, 43537, United States
Alliance for Multispecialty Research, LLC
Norman, Oklahoma, 73069, United States
Heritage Valley Multispecialty Group, Inc
Beaver, Pennsylvania, 15009, United States
Northeast Clinical Research Center
Bethlehem, Pennsylvania, 18017, United States
Capital Area Research, LLC
Camp Hill, Pennsylvania, 17011, United States
Geisinger Medical Center
Danville, Pennsylvania, 17822, United States
Lancaster General Hospital
Lancaster, Pennsylvania, 17602, United States
Clinical Renal Associates Ltd.
Media, Pennsylvania, 19063, United States
Clinical Research of Philadelphia
Philadelphia, Pennsylvania, 19114, United States
Tristar Clinical Investigations
Philadelphia, Pennsylvania, 19114, United States
Preferred Primary Care Physicians, Preferred Clinical Research-St. Clair
Pittsburgh, Pennsylvania, 15243, United States
Guthrie Medical Group, P.C.
Sayre, Pennsylvania, 18840, United States
Medical University of South Carolina
Charleston, South Carolina, 29425, United States
Walker Family Care
Little River, South Carolina, 29566, United States
Care Access - Mauldin
Mauldin, South Carolina, 29662, United States
Circle Clinical Research
Sioux Falls, South Dakota, 57104, United States
Alliance for Multispecialty Research, LLC
Knoxville, Tennessee, 37920, United States
Care Access - Memphis 2
Memphis, Tennessee, 38119, United States
IMA Clinical Research Austin
Austin, Texas, 78745, United States
Headlands Research - Brownsville
Brownsville, Texas, 78526, United States
South Texas Clinical Research
Corpus Christi, Texas, 78404, United States
Private Practice - Dr. Osvaldo A. Brusco
Corpus Christi, Texas, 78414, United States
Baylor Soltero CV Research Center
Dallas, Texas, 75226, United States
Velocity Clinical Research, Dallas
Dallas, Texas, 75230, United States
North Texas Endocrine Center
Dallas, Texas, 75231, United States
Renal Disease Research Institute
Dallas, Texas, 75246, United States
UT Southwestern Medical Center
Dallas, Texas, 75390-9302, United States
Soma Clinical Trials
Denison, Texas, 75020, United States
South Texas Research Institute
Edinburg, Texas, 78539, United States
Medresearch Inc
El Paso, Texas, 79902-4646, United States
Diabetes and Thyroid Center of Ft. Worth
Fort Worth, Texas, 76132, United States
Valley Institute of Research - Fort Worth
Fort Worth, Texas, 76164, United States
Juno Research
Houston, Texas, 77040, United States
Biopharma Informatic, LLC
Houston, Texas, 77043, United States
Aqua Research Institute
Houston, Texas, 77058, United States
Northwest Houston Cardiology - Cypress
Houston, Texas, 77070, United States
Clinical Trial Network
Houston, Texas, 77074, United States
PlanIt Research, PLLC
Houston, Texas, 77079, United States
Biopharma Informatic, LLC
Houston, Texas, 77084, United States
Research Physicians Network, LLC
Houston, Texas, 77089, United States
Accurate Clinical Research, Inc
Humble, Texas, 77346, United States
Texas Institute for Kidney and Endocrine Disorders
Lufkin, Texas, 75904, United States
Wellness Clinical Research
McKinney, Texas, 75069, United States
Revival Research Institute, LLC
McKinney, Texas, 75071, United States
PRX Research
Mesquite, Texas, 75149, United States
Southern Endocrinology Associates
Mesquite, Texas, 75149, United States
Clinical Advancement Center
San Antonio, Texas, 78212, United States
Discovery Clinical Trials - San Antonio
San Antonio, Texas, 78229, United States
IMA Clinical Research San Antonio
San Antonio, Texas, 78229, United States
Endeavor Clinical Trials
San Antonio, Texas, 78240, United States
DaVita Clinical Research - North Houston
Shenandoah, Texas, 77384, United States
Medrasa Clinical Research
Wylie, Texas, 75098, United States
Alpine Research Organization
Clinton, Utah, 84015, United States
Alliance for Multispecialty Research, LLC
Layton, Utah, 84041, United States
Synexus Clinical Research US, Inc.
Salt Lake City, Utah, 84106, United States
Utah Kidney Research Institute
Salt Lake City, Utah, 84115, United States
Alliance for Multispecialty Research, LLC
Norfolk, Virginia, 23502, United States
Dominion Medical Associates, Inc.
Richmond, Virginia, 23219, United States
Eastside Research Associates
Redmond, Washington, 98052, United States
Universal Research Group
Tacoma, Washington, 98405, United States
IMA Clinical Research West Virginia
Morgantown, West Virginia, 26505, United States
St. Vincent Hospital d/b/a Prevea Health
Green Bay, Wisconsin, 54303, United States
Clinical Investigation Specialists
Kenosha, Wisconsin, 53144, United States
CONEXA Investigacion Clinica S.A.
Buenos Aires, 1012, Argentina
Centro de Investigaciones Metabólicas (CINME)
Buenos Aires, 1056ABI, Argentina
Buenos Aires Macula S.A
Buenos Aires, 1061, Argentina
Cicemo Srl
Buenos Aires, 1424, Argentina
Cardiología Palermo
Buenos Aires, 1425, Argentina
Stat Research S.A.
Buenos Aires, C1023AAB, Argentina
Investigaciones Medicas Imoba Srl
Buenos Aires, C1056ABH, Argentina
CIPREC
Buenos Aires, C1061AAS, Argentina
CIPREC
Buenos Aires, C1119, Argentina
Centro Médico Viamonte
Buenos Aires, C1120AAC, Argentina
Mautalen Salud e Investigación
Buenos Aires, C1128AAF, Argentina
CEMEDIC
Buenos Aires, C1407GTN, Argentina
Centro Medico Dra. Laura Maffei- Investigacion Clinica Aplicada
Buenos Aires, C1425AGC, Argentina
Fundación Respirar
Buenos Aires, C1426ABP, Argentina
Glenny Corp. S.A.
Buenos Aires, C1430CKE, Argentina
CEMEDIAB
C.a.b.a., C1205AAO, Argentina
CEDIC
CABA, C1060ABN, Argentina
Instituto Médico Especializado (IME)
CABA, C1405BCG, Argentina
Centro Medico Privado CEMAIC
Capital, X5008HHW, Argentina
IDIM - Instituto de Investigaciones Metabólicas
Ciudad de Buenos Aires, C1012AAR, Argentina
Centro Diabetológico Dr. Waitman
Córdoba, 5000, Argentina
Instituto de Investigaciones Clínicas Córdoba
Córdoba, 5000, Argentina
Sanatorio Privado Duarte Quirós
Córdoba, 5002, Argentina
Centro Médico Colón
Córdoba, 5003, Argentina
Centro Medico Privado San Vicente Diabetes
Córdoba, 5006, Argentina
CIDIM-Centro Integral de Diagnostico por Imagenes Marchegiani
Córdoba, X5000AVE, Argentina
CIPADI - Centro Integral de Prevencion y Atencion en Diabetes
Godoy Cruz, M5501ARP, Argentina
Centro de Investigaciones Clínicas Baigorria
Granadero Baigorria, 2152, Argentina
CMD-Centro Médico y Diagnóstico por Imágenes
Junín, 6000, Argentina
Hospital Italiano de La Plata
La Plata, 1900, Argentina
CIMeL
Lanus, B1824KAJ, Argentina
Polo de Salud Vistalba
Lujan de Cuyo, 5509, Argentina
Centro de Investigaciones Médicas Mar del Plata
Mar del Plata, 7600, Argentina
Instituto de Investigaciones Clínicas Mar del Plata
Mar del Plata, B7600FZO, Argentina
Instituto De Investigaciones Clinicas Quilmes
Quilmes, 1878, Argentina
DIM Clínica Privada
Ramos Mejía, B1704ETD, Argentina
Instituto Médico Río Cuarto
Río Cuarto, X5800AEV, Argentina
Fundacion Estudios Clinicos
Rosario, 2000, Argentina
INECO Neurociencias Oroño
Rosario, 2000, Argentina
Instituto Especialidades de la Salud Rosario
Rosario, 2000, Argentina
Instituto Médico Catamarca IMEC
Rosario, 2000, Argentina
Instituto Médico Fundación Grupo Colaborativo Rosario Investigación y Prevención Medica
Rosario, 2000, Argentina
Instituto de Investigaciones Clinicas Rosario
Rosario, S2000CVD, Argentina
Laboratorio de Hemostasia y Trombosis
Rosario, S2000DTB, Argentina
Hospital Provincial del Centenario
Rosario, S2002KDS, Argentina
Centro de Investigaciones Médicas Tucuman
SAN M. de Tucuman, T4000AXL, Argentina
Corporación Médica San Martín
San Martin, 1650, Argentina
Centro Modelo de Cardiología
San Miguel de Tucumán, 4000, Argentina
Investigaciones Clínicas Tucumán
San Miguel de Tucumán, 4000, Argentina
Go Centro Medico San Nicolás
San Nicolás, 2900, Argentina
Centro de Diagnóstico y Rehabilitación (CEDIR)
Santa Fe, 3000, Argentina
Clínica de Nefrología, Urología y Enfermedades Cardiovasculares
Santa Fe, 3000, Argentina
Centro de Investigaciones Clinicas del Litoral
Santa Fe, S3000FWO, Argentina
Centro de Salud e Investigaciones Médicas
Santa Rosa, 6300, Argentina
Sanatorio Norte
Santiago del Estero, 4200, Argentina
Centro de Investigaciones Medicas Temperley
Temperley, 1834, Argentina
Sanatorio San Martin
Venado Tuerto, 2600, Argentina
CEREHA
Villa Domínico, 1874, Argentina
Instituto de Investigaciones Clinicas Zarate
Zárate, B2800DGH, Argentina
Nightingale Research
Adelaide, 5000, Australia
Emeritus Research
Botany, 2019, Australia
Box Hill Hospital
Box Hill, 3128, Australia
Royal Brisbane and Women's Hospital
Brisbane, 4029, Australia
Northern Beaches Clinical Research
Brookvale, 2100, Australia
Emeritus Research
Camberwell, 3124, Australia
Canberra Hospital
Garran, 2605, Australia
Barwon Health
Geelong, 3220, Australia
Austin Health - Repatriation Hospital
Heidelberg West, 3081, Australia
Logan Hospital
Meadowbrook, 4131, Australia
The Alfred Hospital
Melbourne, 3004, Australia
The AIM Centre / Hunter Diabetes Centre
Merewether, 2291, Australia
Fiona Stanley Hospital
Murdoch, 6150, Australia
Southern Adelaide Diabetes & Endocrine Services
Oaklands Park, 5046, Australia
Royal North Shore Hospital
St Leonards, 2065, Australia
University of Sydney - Charles Perkins Centre
Sydney, 2006, Australia
Krankenhaus St. Josef Braunau
Braunau am Inn, 5280, Austria
VIVIT
Feldkirch, 6800, Austria
Medizinische Universität Graz
Graz, 8036, Austria
Medizinische Universitaet Innsbruck
Innsbruck, 6020, Austria
Konventhospital der Barmherzigen Brüder Linz
Linz, 4021, Austria
Cardio Metabolic Centre
Mattersburg, 7210, Austria
Private Practice - Dr. Evelyn Fliesser-Gorzer
Sankt Stefan ob Stainz, 8511, Austria
Klinik Landstraße
Vienna, 1030, Austria
Zentrum für klinische Studien Dr Hanusch Gmbh
Vienna, 1060, Austria
Universitaetsklinikum Allgemeines Krankenhaus Wien
Vienna, 1090, Austria
Klinik Hietzing
Vienna, 1130, Austria
Imed19-privat
Vienna, 1190, Austria
AZORG Campus Aalst-Moorselbaan
Aalst, 9300, Belgium
ANIMA Research
Alken, 3570, Belgium
Imelda General Hospital
Bonheiden, 2820, Belgium
Algemeen Ziekenhuis klina
Brasschaat, 2930, Belgium
Centre Hospitalier Universitaire Brugmann
Brussels, 1020, Belgium
Université Libre de Bruxelles - Hôpital Erasme
Brussels, 1070, Belgium
UZ Brussel
Brussels, 1090, Belgium
Cliniques universitaires Saint-Luc
Brussels, 1200, Belgium
Antwerp University Hospital
Edegem, 2650, Belgium
UZ Gent
Ghent, 9000, Belgium
Jessa Ziekenhuis
Hasselt, 3500, Belgium
Jan Yperman Ziekenhuis
Ieper, 8900, Belgium
Kormont
Kluisbergen, 9690, Belgium
AZ Groeninge Campus Kennedylaan
Kortrijk, 8500, Belgium
UZ Leuven
Leuven, 3000, Belgium
Centre Hospitalier Universitaire de Liège - Domaine Universitaire du Sart Tilman
Liège, 4000, Belgium
ZNA Jan Palfijn
Merksem, 2170, Belgium
Az Damiaan vzw
Ostend, 8400, Belgium
Artsenpraktijk OHIO
Oudenaarde, 9700, Belgium
Private Practice - Dr. De Watertoren
Tielt, 8700, Belgium
Private Practice - Dr. Tim Decraecke (Zwalm)
Zwalm, 9630, Belgium
Centro de Pesquisa Clinica do Coracao
Aracaju, 49055-530, Brazil
Hospital Universitário João de Barros Barreto
Belém, 66073-000, Brazil
Santa Casa de Misericordia de Belo Horizonte
Belo Horizonte, 30150-221, Brazil
Freire Pesquisa Clínica
Belo Horizonte, 30150-320, Brazil
AngioKormann Blumenau
Blumenau, 89020-430, Brazil
L2IP - Instituto de Pesquisas Clínicas
Brasília, 70200730, Brazil
Chronos Pesquisa Clínica
Brasília, 72145-450, Brazil
Instituto de Pesquisa clinica de Campinas
Campinas, 13060-080, Brazil
Centro de Pesquisa Sao Lucas
Campinas, 13060-803, Brazil
Centro de Endocrinologia Geloneze
Campinas, 13073-350, Brazil
Fundação Universidade de Caxias do Sul (FUCS)
Caxias do Sul, 95070-560, Brazil
Cline Research Center
Curitiba, 80030-480, Brazil
Quanta Diagnóstico e Terapia
Curitiba, 80040-110, Brazil
PUC Trials- Nucleo de Pesquisa clinica da Escola de Medicina da PUCPR
Curitiba, 80230-130, Brazil
Instituto Pro Renal Brasil
Curitiba, 80240-220, Brazil
Centro de Diabetes Curitiba
Curitiba, 80810-040, Brazil
Instituto de Ensino e Pesquisa Clinica do Ceara
Fortaleza, 60.125-058, Brazil
Instituto de Estudos e Pesquisas Clinicas do Ceara IEP-CE
Fortaleza, 60160-230, Brazil
Private Practice - Dr.Miguel N. Hissa
Fortaleza, 60430-350, Brazil
Universidade Federal de Goias
Goiânia, 74605-020, Brazil
Centro de Pesquisas Clínicas Dr. Marco Mota
Maceió, 57051-160, Brazil
CPHOSP Manaus Medicina, Ensino e Pesquisa
Manaus, 69057-088, Brazil
Centro de Pesquisa Clínica de Marília - CPCLIM
Marília, 17504-072, Brazil
Instituto Méderi de Pesquisa e Saúde
Passo Fundo, 99010-120, Brazil
Núcleo de Pesquisa Clínica do Rio Grande do Sul
Porto Alegre, 90430-001, Brazil
IBPClin - Instituto Brasil de Pesquisa Clínica
Rio de Janeiro, 20241-180, Brazil
Ruschel Medicina e Pesquisa Clínica
Rio de Janeiro, 22270-060, Brazil
Hospital Pro-Cardiaco
Rio de Janeiro, 22280-003, Brazil
Clinica Senhor do Bonfim CSB - Salvador
Salvador, 40415-065, Brazil
Pesquisare Saude
Santo André, 09080-110, Brazil
Praxis Pesquisa Medica
Santo André, 09790790, Brazil
Centro Multidisciplinar de Estudos Clinicos
São Bernardo do Campo, 09715-090, Brazil
Fundação Faculdade Regional de Medicina de São José do Rio Preto
São José do Rio Preto, 15090000, Brazil
ISPEM - Instituto São José dos Campos em Pesquisas Médicas
São José dos Campos, 12243-280, Brazil
Instituto de Pesquisa Clinica
São Paulo, 01223-001, Brazil
CPQuali Pesquisa Clínica
São Paulo, 01228-000, Brazil
CPCLIN
São Paulo, 01228-200, Brazil
BR Trials - Ensaios Clinicos e Consultoria
São Paulo, 01236030, Brazil
BP - A Beneficencia Portuguesa de São Paulo
São Paulo, 01321-001, Brazil
Hospital Alemao Oswaldo Cruz
São Paulo, 01323-903, Brazil
IBCC - Núcleo de Pesquisa e Ensino
São Paulo, 04014-002, Brazil
CEPIC - Centro Paulista de Investigação Clínica
São Paulo, 04266-010, Brazil
Hospital das Clinicas FMUSP
São Paulo, 05403-000, Brazil
Incor - Instituto do Coracao
São Paulo, 05403-000, Brazil
Instituto de Molestias Cardiovasculares de Tatui
Tatuí, 18270-170, Brazil
Eurolatino Pesquisas Medicas
Uberlândia, 38400-500, Brazil
CEDOES
Vitória, 29055450, Brazil
Integral Pesquisa e Ensino
Votuporanga, 15500-269, Brazil
C-health Research
Calgary, T2V 4J2, Canada
Ecogene-21
Chicoutimi, G7H 7K9, Canada
Med Trust Research
Courtice, L1E 2J5, Canada
C-health
Edmonton, T6H 2L4, Canada
St. Joseph's Health Care
London, N6A 4V2, Canada
Victoria Hospital & Children's Hospital - London Health Sciences Centre
London, N6A 5W9, Canada
Western Centre for Public Health and Family Medicine
London, N6G 2M1, Canada
G A Research Associates
Moncton, E1G 1A7, Canada
North York Diagnostic and Cardiac Centre
North York, M6B 3H7, Canada
Lakeridge Health
Oshawa, L1G 2B9, Canada
Alpha Recherche Clinique
Québec, G2J 0C4, Canada
Unité de Recherche Clinique du CISSS des Laurentides
Saint-Jérôme, J7Z 2V4, Canada
Ocean West Research Clinic
Surrey, V3S 2N6, Canada
SMH Cardiology Clinical Trials
Surrey, V3V 0C6, Canada
Care Access - Cape Breton
Sydney, B1M 0A1, Canada
Care Access - Thunder Bay - Barton Street
Thunder Bay, P7B 7C7, Canada
Corcare
Toronto, M1B 5N1, Canada
Toronto General Hospital
Toronto, M5G 2C4, Canada
Clinical Research Solutions - Kitchener
Waterloo, N2T 0C1, Canada
Winchester District Memorial Hospital
Winchester, K0C 2K0, Canada
Seven Oaks General Hospital
Winnipeg, R2V 3M3, Canada
Winnipeg Clinic
Winnipeg, R3C 0N2, Canada
MEDICUS SERVICES s.r.o., kardiologicka ambulance
Brandýs nad Labem, 250 01, Czechia
Fakultni Nemocnice u sv. Anny v Brne
Brno, 602 00, Czechia
UNIVMED
Brno, 602 00, Czechia
Fakultni Nemocnice u sv. Anny v Brne
Brno, 60200, Czechia
Vojenská Nemocnice Brno
Brno, 636 00, Czechia
Kardio Chlumec
Chlumec nad Cidlinou, 503 51, Czechia
Nemocnice Cesky Krumlov
Český Krumlov, 381 01, Czechia
Diahaza s.r.o.
Holešov, 769 01, Czechia
Kardioma
Kolín, 280 02, Czechia
Kardiologicka ambulance
Litovel, 784 01, Czechia
EDUMED - Náchod
Náchod, 547 01, Czechia
Agentura Science Pro
Olomouc, 779 00, Czechia
Diabetologicke centrum s.r.o.
Olomouc, 779 00, Czechia
PreventaMed
Olomouc, 779 00, Czechia
Private Practice - Dr. Miroslav Koliba
Ostrava, 702 00, Czechia
Donmed s.r.o.
Ostrava, 710 00, Czechia
Kardiologicka a Angiologicka Ambulance
Ostrava - Dubina, 700 30, Czechia
MUDr. Jana Parkanyiova
Prague, 110 00, Czechia
Synexus Czech
Prague, 120 00, Czechia
MEDICON
Prague, 140 00, Czechia
Fakultni Thomayerova nemocnice
Prague, 14059, Czechia
Nefrologie
Prague, 149 00, Czechia
Poliklinika Lípa Centrum
Prague, 158 00, Czechia
FLEDIP - Na dlouhem lanu
Prague, 160 00, Czechia
Centrum Kardiovaskularni Mediciny
Prague, 169 00, Czechia
Diabetologie a endokrinologie, J.Venerová
Prague, 169 00, Czechia
ResTrial s.r.o.
Prague, 18100, Czechia
MUDr. Barbora Diepoltova
Praha 9 - Klanovice, 190 14, Czechia
Diakom, s.r.o. - Přeštice
Přeštice, 334 01, Czechia
Kardiologicka ambulance MUDr. Ferkl s.r.o.
Trutnov, 541 01, Czechia
Clinical Trials Service s.r.o.
Uherské Hradiště, 686 01, Czechia
Cardio Research, s.r.o
Zlín, 760 01, Czechia
Sygehus Sønderjylland i Aabenraa
Aabenraa, 6200, Denmark
Aarhus Universitetshospital, Skejby
Aarhus, 8200, Denmark
Sanos Clinic - Nordjylland
Gandrup, 9362, Denmark
Herlev and Gentofte Hospital
Herlev, 2730, Denmark
Sanos Clinic
Herlev, 2730, Denmark
Sanos Clinic - Syddanmark
Vejle, 7100, Denmark
Centre Hospitalier Universitaire - Hôpitaux de Rouen - Hôpital de Bois-Guillaume
Bois-Guillaume, 76230, France
Bordeaux University Hospital - Pellegrin
Bordeaux, 33076, France
Chu Gabriel Montpied
Clermont-Ferrand, 63000, France
Centre Hospitalier Sud Francilien
Corbeil-Essonnes, 91106, France
Chu Grenoble Alpes
La Tronche, 38700, France
Centre Hospitalier Louis Pasteur
Le Coudray, 28630, France
CHU Montpellier Lapeyronie Hospital
Montpellier, 34295, France
Hôpital Nord Guillaume-et-René-Laennec / CHU de Nantes
Nantes, 44093, France
Centre Hospitalier Universitaire de Nice - Hopital Pasteur
Nice, 06000, France
Pitie Salpetriere University Hospital
Paris, 75013, France
Groupe hospitalier Paris saint Joseph
Paris, 75014, France
Hôpital Européen Georges Pompidou
Paris, 75015, France
CHU Bordeaux Haut-Leveque
Pessac, 33600, France
CHU Rangueil
Toulouse, 31059, France
Centre Hospitalier Régional Universitaire de Tours - Hôpital Bretonneau
Tours, 37000, France
Polyclinique Vauban
Valenciennes, 59300, France
Kerckhoff-Klinik
Bad Nauheim, 61231, Germany
Herz - und Diabeteszentrum Nordrhein - Westfalen, Bad Oeynhausen
Bad Oeynhausen, 32545, Germany
FutureMeds GmbH
Berlin, 10629, Germany
Kardiologisch-Angiologische Praxis - Herzzentrum Bremen
Bremen, 28277, Germany
St.-Johannes-Hospital Dortmund
Dortmund, 44137, Germany
Hausärztlich-Kardiologisches MVZ am Felsenkeller GmbH/Zentrum für klinische Studien
Dresden, 01277, Germany
Universitaetsklinikum Carl Gustav Carus Dresden
Dresden, 01307, Germany
ZKS Suedbrandenburg
Elsterwerda, 04910, Germany
InnoDiab Forschung Gmbh
Essen, 45136, Germany
Unterfrintroper Hausarztzentrum Klinische Forschung
Essen, 45359, Germany
Universitätsklinikum Frankfurt Goethe-Universität
Frankfurt, 60590, Germany
Diabetes Zentrum Wilhelmsburg
Hamburg, 21109, Germany
Diabetes Zentrum Wandsbek
Hamburg, 22041, Germany
Zentrum für Nieren-, Hochdruck- und Stoffwechselerkrankungen - Heidering
Hanover, 30625, Germany
AmBeNet GmbH
Leipzig, 04107, Germany
Universität zu Lübeck - Institut für Endokrinologie und Diabetes
Lübeck, 23562, Germany
Universitätsmedizin Johannes Gutenberg Universität Mainz
Mainz, 55131, Germany
CRS Clinical Research Services Mannheim
Mannheim, 68167, Germany
Universitätsmedizin Mannheim
Mannheim, 68167, Germany
Institut für Diabetesforschung GmbH Münster
Münster, 48145, Germany
RED-Institut GmbH
Oldenburg, 23758, Germany
Kardiologische Praxis Papenburg
Papenburg, 26871, Germany
Zentrum für klinische Studien
Saint Ingbert, 66386, Germany
Nephrologisches Zentrum Villingen-Schwenningen
Villingen-Schwenningen, 78052, Germany
Praxis Sauter & Sauter & Vorbach
Wangen, 88239, Germany
Athens Medical Center - Psychikon branch
Athens, 115 25, Greece
General Hospital of Athens "G. Gennimatas"
Athens, 11527, Greece
General Hospital of Athens Laiko
Athens, 11527, Greece
Athens Medical Center
Athens, 151 25, Greece
University Hospital of Ioannina
Ioannina, 455 00, Greece
University General Hospital of Larissa
Larissa, 41110, Greece
Iatriko Paleou Falirou Medical Center
Palaió Fáliro, 17562, Greece
G. Gennimatas General Hospital of Thessaloniki
Thessaloniki, 546 35, Greece
Euromedica General Clinic of Thessaloniki
Thessaloniki, 546 45, Greece
Papageorgiou General Hospital of Thessaloniki
Thessaloniki, 564 03, Greece
424 Military General Training Hospital
Thessaloniki, 564 29, Greece
DRC Gyógyszervizsgáló Központ
Balatongyörök, 8313, Hungary
Szent Margit Rendelintézet
Budapest, 1032, Hungary
Óbudai Egészségügyi Centrum
Budapest, 1036, Hungary
Eszak-Pesti Centrumkorhaz-Honvedkorhaz
Budapest, 1062, Hungary
PVN Kutató Kft
Budapest, 1102, Hungary
Semmelweis University
Budapest, 1122, Hungary
Privát Doktor Egészségügyi Zrt
Budapest, 1132, Hungary
Újpesti Egészségügyi Nonprofit Kft
Budapest, H-1046, Hungary
Debreceni Egyetem Klinikai Kozpont
Debrecen, 4032, Hungary
CRU Early Phase Unit
Kistarcsa, 2143, Hungary
Selye János Kórház
Komárom, 2900, Hungary
Szegedi Tudományegyetem Szent-Györgyi Albert Klinikai Központ
Szeged, 6725, Hungary
Allergo-Derm Bakos Kft
Szolnok, 5000, Hungary
Zala Megyei Szent Rafael Kórház
Zalaegerszeg, 8900, Hungary
Motilal Nehru Medical College Hospital
Allahābād, 211002, India
Life Care Hospital and Research Centre
Bangalore, 560092, India
All India Institute of Medical Sciences
Bhubaneswar, 751019, India
Sardar Patel Medical College
Bikaner, 334001, India
Medway Hospitals - Kodambakkam
Chennai, 600024, India
Shri Mahant Indiresh Hospital
Dehradun, 248001, India
Endolife Speciality Hospitals
Guntur, 522001, India
K care Hospital
Kanpur, 208001, India
LPS Institute of Cardiology
Kanpur, 208019, India
Government Medical College - Kozhikode
Kozhikode, 673008, India
Dr. Ram Manohar Lohia Institute of Medical Sciences
Lucknow, 226010, India
Manipal Hospitals
Mysore, 570015, India
Kingsway Hospitals (Best Multispeciality Hospital in Nagpur)
Nagpur, 440001, India
Shrikrishna Hrudayalaya And Critical Care Center
Nagpur, 440012, India
All India Institute of Medical Sciences (AIIMS) - Nagpur
Nagpur, 441108, India
G.B. Pant Institute of Postgraduate Medical Education & Research
New Delhi, 110002, India
Sir Ganga Ram Hospital
New Delhi, 110060, India
Nirmal Hospital Pvt Ltd.
Surat, 395002, India
Shri Bachubhai Dahyabhai Mehta Mahavir Heart Institute
Surat, 395002, India
Barzilai Medical Center
Ashkelon, 7830604, Israel
Rambam Health Care Campus
Haifa, 3109601, Israel
Bnai Zion Medical Center
Haifa, 3339419, Israel
Shaare Zedek Medical Center
Jerusalem, 9013102, Israel
Hadassah Medical Center
Jerusalem, 9112001, Israel
Meir Medical Center
Kfar Saba, 4428164, Israel
Galilee Medical Center
Nahariya, 2210001, Israel
Rabin Medical Center
Petah Tikva, 49100, Israel
Rabin Medical Center - Hasharon Campus
Petah Tikva, 4937211, Israel
Rabin Medical Center
Petah Tikva, 4941492, Israel
Sheba Medical Center
Ramat Gan, 5262100, Israel
Kaplan Medical Center
Rehovot, 7610001, Israel
Sourasky Medical Center
Tel Aviv, 6423906, Israel
Maccabi Healthcare Services
Tel Aviv, 68125, Israel
Diabetes Medical Center
Tel Aviv, 6937947, Israel
Yitzhak Shamir Medical Center
Ẕerifin, 70300, Israel
IRCCS - AOU di Bologna
Bologna, 40138, Italy
IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico di Sant'Orsola
Bologna, 40138, Italy
Azienda Ospedaliero Universitaria S.Anna
Ferrara, 44124, Italy
Ospedale San Martino
Genova, 16132, Italy
Centro Cardiologico Monzino
Milan, 20138, Italy
Ospedale San Raffaele
Milan, 20132, Italy
A.O.U. Policlinico Paolo Giaccone
Palermo, 90127, Italy
AO Santa Maria della Misericordia
Perugia, 06132, Italy
Azienda Ospedaliera Universitaria Pisana
Pisa, 56124, Italy
Azienda Ospedaliero Universitaria Pisana
Pisa, 56126, Italy
AOU Policlinico Umberto I
Roma, 00161, Italy
Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro Cuore
Roma, 00168, Italy
Fondazione Policlinico Universitario Campus Bio-Medico
Rome, 00128, Italy
IRCCS Policlinico San Donato
San Donato Milanese, 20097, Italy
Centro de Atencion al Diabetico Actopan
Actopan, 42500, Mexico
Fundación Cardiovascular de Aguascalientes A.C.
Aguascalientes, 20230, Mexico
Centro de Estudios de Investigacion Metabolicos y Cardiovasculares
Ciudad Madero, 89440, Mexico
Cryptex Investigación Clínica S.A. de C.V.
Cuauhtémoc, Ciudad de México, 06100, Mexico
Instituto de Diabetes, Obesidad y Nutricion
Cuernavaca, 62250, Mexico
Investigación Clínica Cuernavaca, S.C.
Cuernavaca, 62448, Mexico
Instituto de Investigaciones Aplicadas a la Neurociencia A.C.
Durango, 34000, Mexico
Lahoja. Asociacion Para La Investigacion Y La Farmacovigilancia
Durango, 34000, Mexico
Instituto Jalisciense de Investigacion en Diabetes y Obesidad
Guadalajara, 04460, Mexico
Diseno y Planeacion en Investigacion Medica
Guadalajara, 44130, Mexico
Centro de Investigación Clínica y Medicina Traslacional (CIMeT)
Guadalajara, 44340, Mexico
Private Practice - Dr. Arechavaleta Granell Maria del Rosario
Guadalajara, 44670, Mexico
Virgen Cardiovascular Research SC
Guadalajara, 44670, Mexico
CINVEC Medica
Guadalajara, 44690, Mexico
Instituto Cardiovascular de León S.C.
León, 37530, Mexico
Centro de Investigacion en Artritis y Osteoporosis SC
Mexicali, 21200, Mexico
Hospital de Jésus, I.A.P.
Mexico City, 06090, Mexico
Clinica Omega
Mexico City, 06700, Mexico
Centro Especializado En Diabetes, Obesidad Y Prevencion De Enfermedades Cardiovasculares
Mexico City, 11650, Mexico
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Mexico City, 14080, Mexico
EME RED Hospitalaria
Mérida, 97000, Mexico
Medical Care and Research SA de CV
Mérida, 97070, Mexico
Clinstile, S.A. de C.V.
México, 06700, Mexico
Instituto Nacional de Cardiologia Ignacio Chavez
México, 14080, Mexico
Servicios de Oncología Medica Integral - Monterrey - José Benitez
Monterrey, 64040, Mexico
Cardiolink Clin Trials
Monterrey, 64060, Mexico
IMED Internal Medicine Clin Trials
Monterrey, 64060, Mexico
UBAM Unidad Biomedica Avanzada Monterrey
Monterrey, 64460, Mexico
Clínica García Flores SC
Monterrey, 64610, Mexico
Hospital Universitario "Dr. Jose Eleuterio Gonzalez"
Monterrey, 66460, Mexico
Centro de Investigacion Clinica de Oaxaca
Oaxaca City, 68020, Mexico
Boca Clinical Trials Mexico SC
Puebla City, 72160, Mexico
Centro de Estudios Clínicos de Querétaro (CECLIQ)
Querétaro, 76000, Mexico
PanAmerican Clinical Research - Querétaro - Avenida Antea
Querétaro, 76090, Mexico
Centro de Atención e Investigación Cardiovascular del Potosí
San Luis Potosí City, 78200, Mexico
Centro de investigación y control metabólico
San Nicolás de los Garza, 66465, Mexico
Medimanage Research
Tlalpan, 14050, Mexico
Instituto Veracruzano en Investigación Clínica S.C.
Veracruz, 91851, Mexico
Arké SMO S.A de C.V
Veracruz, 91900, Mexico
FAICIC S. de R.L. de C.V.
Veracruz, 91900, Mexico
Consultorio de Medicina Especilizada del Sector Privado
Xalapa, 91193, Mexico
Noordwest Ziekenhuisgroep
Alkmaar, 1815 JD, Netherlands
EB Medical Research
Almere Stad, 1311 RL, Netherlands
Meander Medisch Centrum
Amersfoort, 3813 TZ, Netherlands
OLVG Oost
Amsterdam, 1091 AC, Netherlands
Amsterdam UMC, locatie AMC
Amsterdam, 1105 AZ, Netherlands
Gelre Ziekenhuis
Apeldoorn, 7334 DZ, Netherlands
Rode Kruis Ziekenhuis
Beverwijk, 1942 LE, Netherlands
Amphia Ziekenhuis, locatie Breda Molengracht
Breda, 4818 CK, Netherlands
Het Van Weel-Bethesda Ziekenhuis - Ziekenhuis Dirksland
Dirksland, 3247 BW, Netherlands
Albert Schweitzer Ziekenhuis, locatie Dordwijk
Dordrecht, 3318 AT, Netherlands
Ziekenhuis Gelderse Vallei
Ede, 6716 RP, Netherlands
Catharina Ziekenhuis
Eindhoven, 5623 EJ, Netherlands
Medisch Spectrum Twente
Enschede, 7512 KZ, Netherlands
Spaarne Gasthuis, Haarlem Zuid
Haarlem, 2035 RC, Netherlands
Atrium-Orbis - Zuyderland Medisch Centrum Heerlen
Heerlen, 6419 PC, Netherlands
Ziekenhuis Bethesda
Hoogeveen, 7909 AA, Netherlands
Medische Centrum Leeuwarden
Leeuwarden, 8934 AD, Netherlands
Radboudumc
Nijmegen, 6525 GA, Netherlands
Bravis Ziekenhuis, locatie Roosendaal
Roosendaal, 4708 AE, Netherlands
Franciscus Gasthuis & Vlietland, Locatie Gasthuis
Rotterdam, 3045 PM, Netherlands
Medisch Centrum Thomsonplein
The Hague, 2565 KV, Netherlands
Huisartsenpraktijk Disha
The Hague, 2572 GM, Netherlands
Ziekenhuis Rivierenland
Tiel, 4002 WP, Netherlands
Universitair Medisch Centrum Utrecht
Utrecht, 3584 CX, Netherlands
VieCuri Medisch Centrum, locatie Venlo
Venlo, 5912 BL, Netherlands
Huisartsenpraktijk Broekman
Zwijndrecht, 3333 GZ, Netherlands
Dokters van Nederhoven
Zwijndrecht, 3334 SB, Netherlands
Isala, locatie Zwolle
Zwolle, 8025 AB, Netherlands
Pacific Clinical Research Network - Auckland (PCRN Auckland)
Auckland, 0622, New Zealand
Aotearoa Clinical Trials
Auckland, 2025, New Zealand
Pacific Clinical Research Network - Tasman
Nelson, 7011, New Zealand
Lakeland Clinical Trials Culloden
Papamoa, 3118, New Zealand
Momentum Clinical Research - Pukekohe
Pukekohe, 2120, New Zealand
PCRN Silverdale Medical
Silverdale, 0932, New Zealand
Momentum Clinical Research - Tauranga
Tauranga, 3110, New Zealand
Lakeland Clinical Trials Wellington
Upper Hutt, 5018, New Zealand
Aotearoa Clinical Trials - Whangarei
Whangarei, 0110, New Zealand
KLIMED Marek Klimkiewicz
Bialystok, 15-704, Poland
Polsko-Amerykańskie Kliniki Serca II Oddział Kardiologiczny
Bielsko-Biala, 43-300, Poland
NZOZ Centrum Medyczne KERmed
Bydgoszcz, 85-231, Poland
Centrum Medyczne INTERCOR Sp. z o.o.
Bydgoszcz, 85-605, Poland
Diab Serwis Popenda Spółka Jawna
Chorzów, 41-500, Poland
Polsko-Amerykańskie Kliniki Serca PAKS Małopolskie Centrum Sercowo-Naczyniowe
Chrzanów, 32-500, Poland
Centrum Kliniczno-Badawcze
Elblag, 82-300, Poland
Uniwersyteckie Centrum Kliniczne
Gdansk, 80-952, Poland
Medyczne Centrum Diabetologiczno Endokrynologiczno Metaboliczne DIAB-ENDO-MET
Krakow, 31-261, Poland
Poliklinika Kardiologiczna Serce
Leszno, 64-100, Poland
Pro Salus Centrum Medyczne
Lodz, 91-473, Poland
CenterMed Lublin NZOZ
Lublin, 20-044, Poland
Ekamed
Lublin, 20-718, Poland
EndoPractica
Opole, 45-301, Poland
Centrum Zdrowia Metabolicznego Pawel Bogdanski
Poznan, 60-589, Poland
Wojewodzki Szpital im. Sw. Ojca Pio w Przemyslu
Przemyśl, 37-700, Poland
Centrum Szybkiej Diagnostyki Kardiologicznej "Kardiomed" M. Żabówka E. Żabówka
Tarnów, 33-100, Poland
Polsko-Amerykańskie Kliniki Serca
Tychy, 43-100, Poland
Balsam Medica
Warsaw, 01-249, Poland
NZOZ Centurm Medyczne SERAFIN-MED
Żarów, 58-130, Poland
Advanced Clinical Research, LLC
Bayamón, 00959, Puerto Rico
Clinical Research Management Group Inc
Ponce, 00733, Puerto Rico
GCM Medical Group, PSC - Hato Rey Site
San Juan, 00917, Puerto Rico
CMI Cardiologie - Dr. Mercea Corina Delia
Baia Mare, 430124, Romania
CMI DNBM Dr. Pop Lavinia
Baia Mare, 430222, Romania
C.M.D.T.A. Neomed
Brasov, 500283, Romania
Nicodiab
Bucharest, 010507, Romania
Hightech Medical Services SRL-Centrul pentru Studiul Metabolismului
Bucharest, 011053, Romania
Centrul Medical NutriLife
Bucharest, 013764, Romania
Lotus-Med Tunari
Bucharest, 020528, Romania
Centrul Medical Endocrinologie si Diabet Dr. Paveliu
Bucharest, 50538, Romania
Spitalul Clinic Județean de Urgență
Craiova, 200642, Romania
Milena Sante
Galați, 800001, Romania
Diamed Obesity
Galați, 800291, Romania
Centrul Medical Consultmed
Iași, 700547, Romania
Cardiomed Iași
Iași, 700687, Romania
Clinica Korall
Satu Mare, 440055, Romania
Policlinica Astra Sibiu
Sibiu, 550371, Romania
SC Dentosim Queen SRL - Centrul Medical Diamed
Târgu Mureş, 540098, Romania
Centrul Medical Mediab
Târgu Mureş, 540142, Romania
Mediab S.R.L.
Târgu Mureş, 540142, Romania
Cabinet Medical Dr.Geru
Timișoara, 300288, Romania
Institutul de Boli Cardiovasculare Timișoara
Timișoara, 300310, Romania
Centrul Medical Medicalis
Timișoara, 300462, Romania
Cliniq s.r.o.
Bratislava, 81109, Slovakia
ENDIAMED s.r.o
Dolný Kubín, 026 01, Slovakia
JM-Interna s.r.o
Dolný Kubín, 02601, Slovakia
IN-DIA
Lučenec, 984 01, Slovakia
Nemocnica s poliklinikou Lucenec
Lučenec, 984 01, Slovakia
NEDÚ - Národný endokrinologický a diabetologický ústav n.o.
Ľubochňa, 034 91, Slovakia
Sin Azucar
Malacky, 901 01, Slovakia
AMBORA s.r.o. Interna ambulancia
Martin, 036 01, Slovakia
B-Medical, s.r.o.
Námestovo, 02901, Slovakia
Fakultná nemocnica Nitra
Nitra, 950 01, Slovakia
FUNKYSTUFF s.r.o.
Nové Zámky, 940 02, Slovakia
MEDIKALS
Piešťany, 921 01, Slovakia
MUDr. Judita Gondova
Poltár, 987 01, Slovakia
ENRIN, s.r.o.
Rimavská Sobota, 979 01, Slovakia
Tatratrial s.r.o.
Rožňava, 04801, Slovakia
Areteus s.r.o.
Trebišov, 075 01, Slovakia
MediPrax, s.r.o.
Trstená, 028 01, Slovakia
IRIDIA
Vrútky, 038 61, Slovakia
CHUAC-Complejo Hospitalario Universitario A Coruña
A Coruña, 15006, Spain
Centro Periférico de Especialidades Bola Azul
Almería, 04009, Spain
Hospital Universitario de La Ribera
Alzira, 46600, Spain
Hospital Universitari Vall d'Hebron
Barcelona, 08035, Spain
Complejo Hospitalario Universitario de Ferrol (CHUF)- Hospital Naval
Ferrol, 15405, Spain
Hospital Universitario Virgen de la Victoria
Málaga, 29010, Spain
Hospital Universitario Central de Asturias
Oviedo, 33011, Spain
Clínica Juaneda
Palma de Mallorca, 07014, Spain
Hospital Universitario Quironsalud Madrid
Pozuelo de Alarcón, 28223, Spain
Hospital Universitario Marqués de Valdecilla
Santander, 39008, Spain
Clínica nuevas Tecnologías en Diabetes y Endocrinología (NTDE)
Seville, 41003, Spain
Hospital Quiron Infanta Luisa
Seville, 41010, Spain
Vithas Hospital Sevilla
Seville, 41950, Spain
Hospital Universitario Doctor Peset
Valencia, 46017, Spain
Afyon Kocatepe Üniversitesi Tıp Fakültesi
Afyonkarahisar, 03030, Turkey (Türkiye)
Ankara Bilkent Şehir Hastanesi
Ankara, 06800, Turkey (Türkiye)
Hacettepe Universite Hastaneleri
Ankara, Turkey (Türkiye)
Akdeniz Universitesi Hastanesi
Antalya, 07070, Turkey (Türkiye)
Ege Universitesi Hastanesi
Bornova, 35100, Turkey (Türkiye)
T.C. Saglik Bakanligi - Hitit Universitesi Corum Egitim ve Arastirma Hastanesi
Çorum, 19040, Turkey (Türkiye)
Trakya University Medical Faculty Hospital
Edirne, 22030, Turkey (Türkiye)
Eskisehir Osmangazi University
Eskişehir, 26480, Turkey (Türkiye)
Gaziantep Universitesi Sahinbey Arastirma ve Uygulama Hastanesi
Gaziantep, 27310, Turkey (Türkiye)
Dr. Siyami Ersek Göğüs Kalp Ve Damar Cerrahisi Eğitim Ve Araştırma Hastanesi
Istanbul, 34668, Turkey (Türkiye)
Kartal Koşuyolu Yüksek İhtisas Eğitim ve Araştirma Hastanesi
Istanbul, 34865, Turkey (Türkiye)
Istanbul Universitesi Cerrahpasa
Istanbul- Fatih, 34098, Turkey (Türkiye)
Kocaeli Üniversitesi
İzmit, 41380, Turkey (Türkiye)
Erciyes Universitesi Tıp Fakultesi Hastaneleri
Kayseri, Turkey (Türkiye)
Kocaeli Üniversitesi
Kocaeli, 41380, Turkey (Türkiye)
Necmettin Erbakan University Meram Medical Faculty
Konya, 42080, Turkey (Türkiye)
T.C. Saglik Bakanligi - Dumlupinar Universitesi Kutahya Evliya Celebi Egitim ve Arastirma Hastanesi
Kütahya, 43100, Turkey (Türkiye)
Mersin University
Mersin, 33343, Turkey (Türkiye)
Ondokuz Mayıs Universitesi
Samsun, 55270, Turkey (Türkiye)
Cumhuriyet Universitesi
Sivas, 58140, Turkey (Türkiye)
Bursa Yüksek İhtisas Eğitim Ve Araştırma Hastanesi
Yıldırım, 16310, Turkey (Türkiye)
Regional Communal Non-commercial enterprise "Chernivtsi regional clinical hospital"
Chernivtsi, 58000, Ukraine
Vise Clinic
Ivano-Frankivsk, 76005, Ukraine
Clinical Diagnostic Center
Ivano-Frankivsk, 76018, Ukraine
Institute of Endocrinology and Metabolism named after Komissarenko
Kiev, 04114, Ukraine
Edelweiss Medics
Kyiv, 02002, Ukraine
Medbud Clinic
Kyiv, 03037, Ukraine
Medical Center "Universal Clinic "Oberig" of Limited Liability Company "Kapytal"
Kyiv, 03057, Ukraine
ARTEM
Kyiv, 04050, Ukraine
Center of Family Medicine Plus
Kyiv, 04210, Ukraine
Lviv City Clinical Hospital #4
Lviv, 79005, Ukraine
University Hospital of LNMU
Lviv, 79010, Ukraine
Medical center Pulse in Vinnitsi
Vinnytsia, 21001, Ukraine
Limited liability company "Medical center Health Clinic"
Vinnytsia, 21009, Ukraine
Vinnytsia Regional Clinical Endocrinology Dispensary
Vinnytsia, 21010, Ukraine
Communal Enterprise "Hospital #1" of Zhytomyr City Council
Zhytomyr, 10002, Ukraine
Aberdeen Royal Infirmary
Aberdeen, AB25 2ZN, United Kingdom
FutureMeds - Birmingham
Birmingham, B21 9RY, United Kingdom
FutureMeds - Liverpool
Bromborough, CH62 6EE, United Kingdom
University Hospital Coventry & Warwickshire
Coventry, CV2 2DX, United Kingdom
FutureMeds Glasgow - CPS Research
Glasgow, G20 7BE, United Kingdom
Hull Royal Infirmary
Hull, HU3 2JZ, United Kingdom
Ipswich Hospital
Ipswich, IP4 5PD, United Kingdom
Ashton Medical Group - Chapel House
Lancashire, OL6 6EW, United Kingdom
Royal London Hospital
London, E1 1BB, United Kingdom
Altnagelvin Area Hospital
Londonderry, BT47 6SB, United Kingdom
Futuremeds-Newcastle
Newcastle, NE6 1SG, United Kingdom
Newquay Health Centre
Newquay, TR7 1RU, United Kingdom
Homecroft Surgery
Redruth, TR16 4ET, United Kingdom
FutureMeds Teesside - Middlefield Centre
Stockton-on-Tees, TS19 8PE, United Kingdom
Swansea University
Swansea, SA2 8PP, United Kingdom
Musgrove Park Hospital
Taunton, TA1 5DA, United Kingdom
Rame Group Practice
Torpoint, PL11 2TB, United Kingdom
Moorgreen Hospital
West End, SO30 3JB, United Kingdom
Related Publications (1)
Heerspink HJL, van Raalte DH, Bjornstad P, Bunck MC, Wu P, Tunali I, Milicevic Z, Koeneman L. Rationale, Design, and Baseline Characteristics of the TRANSCEND-CKD trial of Retatrutide in Patients with Chronic Kidney Disease. Nephrol Dial Transplant. 2025 Oct 29:gfaf230. doi: 10.1093/ndt/gfaf230. Online ahead of print.
PMID: 41160422DERIVED
Related Links
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 8 AM - 8 PM Eastern time (UTC/GMT - 5 hours, EST)
Eli Lilly and Company
Study Design
- Study Type
- interventional
- Phase
- phase 3
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, INVESTIGATOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- INDUSTRY
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
April 22, 2024
First Posted
April 25, 2024
Study Start
April 30, 2024
Primary Completion (Estimated)
February 1, 2029
Study Completion (Estimated)
February 1, 2029
Last Updated
April 20, 2026
Record last verified: 2026-04
Data Sharing
- IPD Sharing
- Will share
- Shared Documents
- STUDY PROTOCOL, SAP, CSR
- Time Frame
- Data are available 6 months after the primary publication and approval of the indication studied in the US and European Union (EU), whichever is later. Data will be indefinitely available for requesting.
- Access Criteria
- research proposal must be approved by an independent review panel and researchers must sign a data sharing agreement.
Anonymized individual patient level data will be provided in a secure access environment upon approval of a research proposal and a signed data sharing agreement.