Coronary Arteries Anomalies by CT in Children With CHD

NCT06381128 | Not Yet Recruiting

• 1 other identifier: CAA by CT in children with CHD
• Study Type: observational
• Target: 100
• Locations: 0 countries
• Sites: N/A

Brief Summary

Delineate coronary artery anatomy and detection of coronary anomalies in children with complex cardiac anomalies by cardiac CT-angiography before total surgical correction.

Conditions

Cardiac Congenital Defects

Outcome Measures

Primary Outcomes (1)

• Detection of coronary arteries anomalies by computed tomography angiography in children with congenital heart disease

  Delineate coronary artery anatomy and detection of coronary anomalies in children with complex cardiac anomalies by cardiac CT-angiography before total surgical correction.

  Baseline

Interventions

Cardiac CT RADIATION

Computed tomography angiography

Eligibility Criteria

• Age: 1 Day - 18 Years
• Sex: all
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

-Children aged from 1 day to 18 years old with congenital heart disease and undergoing surgical correction.

You may qualify if:

• Children aged from 1 day to 18 years old with congenital heart disease and undergoing surgical correction.

You may not qualify if:

• Children had isolated coronary anatomy anomalies.
• Children had medical coronary artery disease i.e. Kawasaki disease.
• Children with CHD and not candidate for surgical correction .
• Children with CHD with past history of cardiac surgery.

Sponsors & Collaborators

• Assiut University: lead

Related Publications (17)

• Jacobs ML, Mavroudis C. Anomalies of the coronary arteries: nomenclature and classification. Cardiol Young. 2010 Dec;20 Suppl 3:15-9. doi: 10.1017/S1047951110001046.

  PMID: 21087555 BACKGROUND

• Cheezum MK, Liberthson RR, Shah NR, Villines TC, O'Gara PT, Landzberg MJ, Blankstein R. Anomalous Aortic Origin of a Coronary Artery From the Inappropriate Sinus of Valsalva. J Am Coll Cardiol. 2017 Mar 28;69(12):1592-1608. doi: 10.1016/j.jacc.2017.01.031.

  PMID: 28335843 BACKGROUND

• Mery CM, De Leon LE, Molossi S, Sexson-Tejtel SK, Agrawal H, Krishnamurthy R, Masand P, Qureshi AM, McKenzie ED, Fraser CD Jr. Outcomes of surgical intervention for anomalous aortic origin of a coronary artery: A large contemporary prospective cohort study. J Thorac Cardiovasc Surg. 2018 Jan;155(1):305-319.e4. doi: 10.1016/j.jtcvs.2017.08.116. Epub 2017 Sep 14.

  PMID: 29074047 BACKGROUND

• Vastel-Amzallag C, Le Bret E, Paul JF, Lambert V, Rohnean A, El Fassy E, Sigal-Cinqualbre A. Diagnostic accuracy of dual-source multislice computed tomographic analysis for the preoperative detection of coronary artery anomalies in 100 patients with tetralogy of Fallot. J Thorac Cardiovasc Surg. 2011 Jul;142(1):120-6. doi: 10.1016/j.jtcvs.2010.11.016. Epub 2011 Feb 3.

  PMID: 21292283 BACKGROUND

• Yu FF, Lu B, Gao Y, Hou ZH, Schoepf UJ, Spearman JV, Cao HL, Sun ML, Jiang SL. Congenital anomalies of coronary arteries in complex congenital heart disease: diagnosis and analysis with dual-source CT. J Cardiovasc Comput Tomogr. 2013 Nov-Dec;7(6):383-90. doi: 10.1016/j.jcct.2013.11.004. Epub 2013 Nov 8.

  PMID: 24331934 BACKGROUND

• Secinaro A, Curione D, Mortensen KH, Santangelo TP, Ciancarella P, Napolitano C, Del Pasqua A, Taylor AM, Ciliberti P. Dual-source computed tomography coronary artery imaging in children. Pediatr Radiol. 2019 Dec;49(13):1823-1839. doi: 10.1007/s00247-019-04494-2. Epub 2019 Aug 22.

  PMID: 31440884 BACKGROUND

• Frommelt P, Lopez L, Dimas VV, Eidem B, Han BK, Ko HH, Lorber R, Nii M, Printz B, Srivastava S, Valente AM, Cohen MS. Recommendations for Multimodality Assessment of Congenital Coronary Anomalies: A Guide from the American Society of Echocardiography: Developed in Collaboration with the Society for Cardiovascular Angiography and Interventions, Japanese Society of Echocardiography, and Society for Cardiovascular Magnetic Resonance. J Am Soc Echocardiogr. 2020 Mar;33(3):259-294. doi: 10.1016/j.echo.2019.10.011. No abstract available.

  PMID: 32143778 BACKGROUND

• Goo HW. Coronary artery imaging in children. Korean J Radiol. 2015 Mar-Apr;16(2):239-50. doi: 10.3348/kjr.2015.16.2.239. Epub 2015 Feb 27.

  PMID: 25741188 BACKGROUND

• Lederlin M, Thambo JB, Latrabe V, Corneloup O, Cochet H, Montaudon M, Laurent F. Coronary imaging techniques with emphasis on CT and MRI. Pediatr Radiol. 2011 Dec;41(12):1516-25. doi: 10.1007/s00247-011-2222-0. Epub 2011 Nov 30.

  PMID: 22127683 BACKGROUND

• Hazekamp M. Coronary Anatomy in Congenital Heart Disease: The Important Contributions of Professor Dr. Adriana Gittenberger-de Groot. J Cardiovasc Dev Dis. 2021 Mar 9;8(3):27. doi: 10.3390/jcdd8030027.

  PMID: 33803117 BACKGROUND

• Freire G, Miller MS. Echocardiographic evaluation of coronary arteries in congenital heart disease. Cardiol Young. 2015 Dec;25(8):1504-11. doi: 10.1017/S1047951115002000.

  PMID: 26675597 BACKGROUND

• Malone LJ, Morin CE, Browne LP. Coronary computed tomography angiography in children. Pediatr Radiol. 2022 Dec;52(13):2498-2509. doi: 10.1007/s00247-021-05209-2. Epub 2021 Nov 4.

  PMID: 34734316 BACKGROUND

• Ezzeldin DA, Hafez MS, Mansour A. Multidetector computed tomography for patients with congenital heart disease: a multi-center registry from Africa and Middle East; patients' characteristics and procedural safety. Egypt Heart J. 2021 Oct 16;73(1):90. doi: 10.1186/s43044-021-00217-x.

  PMID: 34655343 BACKGROUND

• Zhang LJ, Zhou CS, Wang Y, Jin Z, Yu W, Zhang Z, Zhang B, Fang X, Cui X, Li K, Huang W, Zheng L, Ji XM, Hoffman C, Schoepf UJ, Lu GM. Prevalence and types of coronary to pulmonary artery fistula in a Chinese population at dual-source CT coronary angiography. Acta Radiol. 2014 Nov;55(9):1031-9. doi: 10.1177/0284185113512299. Epub 2013 Nov 26.

  PMID: 24280135 BACKGROUND

• Chao BT, Wang XM, Wu LB, Chen J, Cheng ZP, Wu DW, Duan YH. Diagnostic value of dual-source CT in Kawasaki disease. Chin Med J (Engl). 2010 Mar 20;123(6):670-4.

  PMID: 20368084 BACKGROUND

• Kashyap JR, Kumar S, Reddy S, Rao K R, Sehrawat O, Kashyap R, Kansal M, Reddy H, Kadiyala V, Uppal L. Prevalence and Pattern of Congenital Coronary Artery Anomalies in Patients Undergoing Coronary Angiography at a Tertiary Care Hospital of Northern India. Cureus. 2021 Apr 10;13(4):e14399. doi: 10.7759/cureus.14399.

  PMID: 33981512 BACKGROUND

• Han BK, Rigsby CK, Hlavacek A, Leipsic J, Nicol ED, Siegel MJ, Bardo D, Abbara S, Ghoshhajra B, Lesser JR, Raman S, Crean AM; Society of Cardiovascular Computed Tomography; Society of Pediatric Radiology; North American Society of Cardiac Imaging. Computed Tomography Imaging in Patients with Congenital Heart Disease Part I: Rationale and Utility. An Expert Consensus Document of the Society of Cardiovascular Computed Tomography (SCCT): Endorsed by the Society of Pediatric Radiology (SPR) and the North American Society of Cardiac Imaging (NASCI). J Cardiovasc Comput Tomogr. 2015 Nov-Dec;9(6):475-92. doi: 10.1016/j.jcct.2015.07.004. Epub 2015 Jul 23.

  PMID: 26272851 BACKGROUND

MeSH Terms

Conditions

Heart Defects, Congenital

Condition Hierarchy (Ancestors)

Cardiovascular Abnormalities; Cardiovascular Diseases; Heart Diseases; Congenital Abnormalities; Congenital, Hereditary, and Neonatal Diseases and Abnormalities

Central Study Contacts

Rehab Mohamed Rashed, Assistant lecturer

CONTACT

01064959241; rehabrashed950@gmail.com

Nagwa Ali Mohamed, Professor

CONTACT

01096260950; nammaali2015@aun.edu.eg

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: RMRGad

Study Record Dates

• First Submitted: April 19, 2024
• First Posted: April 24, 2024
• Study Start: January 1, 2025
• Primary Completion: January 1, 2026
• Study Completion (Estimated): December 31, 2029
• Last Updated: April 24, 2024

Record last verified: 2024-04