Quality of Life Change in Patients Undergoing Parathyroidectomy With End-stage Renal Failure

NCT06378931 | Not Yet Recruiting

• 1 other identifier: 2024HX161
• Study Type: observational
• Target: 80
• Locations: 0 countries
• Sites: N/A

Brief Summary

The purpose of this study is to characterize the quality of life change in patients undergoing parathyroidectomy with secondary hyperparathyroidism due to end-stage renal failure.

Conditions

Secondary Hyperparathyroidism; End Stage Renal Failure

Outcome Measures

Primary Outcomes (1)

• Measure quality of life scores change with respect to time

  Quality of life will be assessed by the 36-Item short form health survey scale, Subjects complete one response from a range of options for each of the 36 questions. A combination of item response is then aggregated to calculate a score for each of the eight dimensions listed. The scores for each dimension range from 0 to 100, with higher scores indicating better health status

  up to 1 year

Secondary Outcomes (3)

• Measure anxiety and depression score change with respect to time

  up to 1 year

• Measure bone pain scores change with respect to time

  up to 1 year

• Length of hospital stay

  through study completion, an average of 1 week

Study Arms (1)

Quality of life change in patients Undergoing Parathyroidectomy with end-stage renal failure

Quality of Life Progression in Patients Undergoing Parathyroidectomy With Secondary Hyperparathyroidism Due to End-stage Renal Failure

Other: Quality of life progression after parathyroidectomy

Interventions

Quality of life progression after parathyroidectomy OTHER

Study the progression of quality of life.

Quality of life change in patients Undergoing Parathyroidectomy with end-stage renal failure

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients scheduled for parathyroidectomy with secondary hyperparathyroidism due to end-stage renal failure will be invited to participate in this study.

You may qualify if:

• Age: ≥18 years old;
• Patients scheduled for parathyroidectomy with secondary hyperparathyroidism due to end-stage renal failure

You may not qualify if:

• Patients refuse to participate

Sponsors & Collaborators

• Chunling Jiang: lead

MeSH Terms

Conditions

Hyperparathyroidism, Secondary; Renal Insufficiency, Chronic

Condition Hierarchy (Ancestors)

Hyperparathyroidism; Parathyroid Diseases; Endocrine System Diseases; Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Chunling Jiang

  West China Hospital

  STUDY DIRECTOR

Central Study Contacts

Chunling Jiang, PhD

CONTACT

18980601096; jiangchunling@scu.edu.cn

Chunling Jiang

CONTACT

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: March 26, 2024
• First Posted: April 23, 2024
• Study Start: April 15, 2024
• Primary Completion: December 30, 2025
• Study Completion: December 30, 2025
• Last Updated: April 23, 2024

Record last verified: 2024-03

Data Sharing

• IPD Sharing: Will not share