Pattern Of Isolated Fungi From Bronchoalveolar Lavage Among Patients With Bronchial Asthma

NCT06376617 | Not Yet Recruiting

• 1 other identifier: MS.24.03.2743
• Study Type: interventional
• Target: 60
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study is to assess the pattern of isolated fungi from the respiratory air way (bronchial tree) from bronchoalvealar lavage (BAL) in asthmatic patients with uncontrolled or difficult to treat asthma

Conditions

Bronchial Asthma

Outcome Measures

Primary Outcomes (1)

• assess the pattern of isolated fungi from the respiratory air way (bronchial tree) from bronchoalvealar lavage (BAL) in asthmatic patients with uncontrolled or difficult to treat asthma

  BAL will stained by fungal staining with lactophenol stain as well as culture on Sabouraud dextrose agar.

  1 year

Study Arms (1)

Study patern of fungal inection which cause excerbation

OTHER

Take bal through fob and send for fungal stain and culure

Device: fibroptic bronchoscopy

Interventions

fibroptic bronchoscopy DEVICE

take bal through fibrooptic bronchoscopy and send for stain and culcure

Also known as: fugnal stain and culcure

Study patern of fungal inection which cause excerbation

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age 18 years or more.
• Patients with Uncontrolled bronchial asthma, frequent exacerbations and difficult to treat symptoms despite adherence to medication.

You may not qualify if:

• Age less than 18 years.
• Patients who do not give consent for the procedure.
• Patients with unstable cardiac conditions (recent myocardial infarction, cardiac arrhythmia, etc.)
• Pregnant women.
• Patient already on antifungal treatment.
• Bleeding profile abnormality.
• patients during acute sever attacks .

Sponsors & Collaborators

• Mansoura University: lead

MeSH Terms

Conditions

Asthma

Condition Hierarchy (Ancestors)

Bronchial Diseases; Respiratory Tract Diseases; Lung Diseases, Obstructive; Lung Diseases; Respiratory Hypersensitivity; Hypersensitivity, Immediate; Hypersensitivity; Immune System Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: lecturer of chest medicine

Model Details: BAL will stained by fungal staining with lactophenol stain as well as culture on Sabouraud dextrose agar.

Study Record Dates

• First Submitted: April 16, 2024
• First Posted: April 19, 2024
• Study Start: April 25, 2024
• Primary Completion: April 20, 2025
• Study Completion: May 20, 2025
• Last Updated: April 19, 2024

Record last verified: 2024-04