The Effectiveness of Bupivacaine and Bupivacaine+Dexmedetomidine Combination in Transversus Abdominis Plane* Block
TAP
Comparison of the Effectiveness of Bupivacaine and Bupivacaine+Dexmedetomidine Combination in Transversus Abdominis Plane* Block in Colorectal Cancer Surgery
1 other identifier
observational
84
1 country
1
Brief Summary
Transversus abdominis plane (TAP) block is an anesthesia method that provides somatic analgesia to the anterior and lateral abdominal walls. Thus, TAP block is widely implemented in perioperative management of colorectal cancer patients. Researchers aimed to evaluate the analgesic effectiveness and duration of effect of dexmedetomidine added to bupivacaine in the TAP block applied in colorectal cancer surgeries.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started May 2024
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
April 13, 2024
CompletedFirst Posted
Study publicly available on registry
April 17, 2024
CompletedStudy Start
First participant enrolled
May 1, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 30, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
November 30, 2024
CompletedApril 17, 2024
April 1, 2024
5 months
April 13, 2024
April 16, 2024
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Analgesic effectiveness of bupivacain and bupivacain+dexmedetomidine combination in colorectal cancer surgery
Numeric Rating Scales of two groups in postoperative period. The numeric rating scale (NRS) is a pain screening tool, commonly used to assess pain severity at that moment in time using a 0-10 scale, with zero meaning "no pain" and 10 meaning "the worst pain imaginable"
postoperative day two
Study Arms (2)
bupivacaine
Ultrasonography (USG) guided bilateral TAP block:20 ml %0,25 concentration bupivacain
bupivacaine+dexmedetomidine
Ultrasonography (USG) guided bilateral TAP block: 20 ml %0,25 concentration bupivacain+ 0.5 mcg/kg dexmedetomidine
Interventions
Ultrasonography (USG) guided bilateralTAP block:20 ml %0,25 concentration bupivacain
Ultrasonography (USG) guided bilateral TAP block: 20 ml %0,25 concentration bupivacain+ 0.5 mcg/kg dexmedetomidine
Eligibility Criteria
The investigators will evaluate colorectal cancer patients from Ankara Dr. Abdurrahman Yurtaslan Oncology Train and Research Hospital who will undergo colorectal cancer surgery. The investigators will exclude patients who no longer want to participate at any part of the trial. A total of 84 patients' data will be collected.
You may qualify if:
- colorectal cancer diagnosis
- undergoing colorectal cancer surgery
You may not qualify if:
- allergic reaction to local anesthetics
- bleeding anomalies
- infection in TAP block area
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Turkey Dr.Abdurrahman Yurtaslan Ankara Oncology Train and Research Hospital
Ankara, Cankaya, 06110, Turkey (Türkiye)
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Beyza Seker, MD
Resident MD
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Resident Anaesthesiologist
Study Record Dates
First Submitted
April 13, 2024
First Posted
April 17, 2024
Study Start
May 1, 2024
Primary Completion
September 30, 2024
Study Completion
November 30, 2024
Last Updated
April 17, 2024
Record last verified: 2024-04