Increasing Engagement With Messages Regarding CRC Screening Among Adults Aged 45-49

NCT05281159 | Completed DMC

• 1 other identifier: CRC45+TEXT
• Study Type: interventional
• Target: 20,509
• Locations: 1 country
• Sites: 2

Brief Summary

In May of 2021, the United States Preventive Service Task Force (USPSTF) updated their colorectal cancer (CRC) screening guidelines by recommending screening at an earlier age for average-risk adults starting at the age of 45 years old (Grade B recommendation). This is in addition to their Grade A recommendations of continuing to screen average-risk adults ages 50-75 years old. As the investigators health system aims to screen the newly eligible population of average-risk patients between the ages of 45-49, the investigators proposed randomized controlled trial is aimed to determine the most effective patient outreach approach to increase patients' engagement with messages regarding CRC screening and screening uptake within this specific age-group.

Conditions

Colorectal Cancer; Colorectal Neoplasms

Keywords

Colorectal Cancer Screening; Behavioral Economics; Colorectal Cancer

Outcome Measures

Primary Outcomes (1)

• Opening link within SMS Text message

  Rate of clicking the link to MyChart within the SMS text message

  1 week after getting the initial text message

Secondary Outcomes (3)

• Opening link within SMS Text Message

  1 month after getting initial text message

• CRC45+ Choice MyChart Message opened

  1 month after getting the initial text message

• Overall completion of any CRC screening test

  6 months after getting the initial text message

Study Arms (3)

Standard of Care

NO INTERVENTION

This group will receive a standard SMS text message indicating that they have a MyChart message from their provider about CRC screening and should follow a link to be screened.

"Risk Information"

EXPERIMENTAL

This group will receive an SMS text message highlighting their risk for CRC.

Behavioral: Risk Information

"Risk Information + Action"

EXPERIMENTAL

This group will receive an SMS message highlighting their risk for CRC and the importance of taking quick action.

Behavioral: Risk Information + Action

Interventions

Risk Information BEHAVIORAL

This group will receive an SMS text message highlighting their risk for CRC on top of the content in the Control arm.

"Risk Information"

Risk Information + Action BEHAVIORAL

This group will receive an SMS text message highlighting their risk for CRC and the importance of taking quick action, on top of the content in the Control arm.

"Risk Information + Action"

Eligibility Criteria

• Age: 45 Years - 49 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• UCLA Health patient
• Age 45-49 (as of 2/1/2022)
• Active primary care provider
• Visit within the last 3 years

You may not qualify if:

• Age \<45 or \>50 years old at time of randomization
• Documented family history of CRC in EMR
• History (personal or family) of prior adenomatous polyps in the EMR
• History of high-risk cancer syndromes (e.g., Lynch, FAP)
• Prior CRC screening with colonoscopy or FIT
• Inactive MyChart status at enrollment
• No documented SMS-capable phone number

Sponsors & Collaborators

• University of California, Los Angeles: lead
• UCLA Vatche and Tamar Manoukian Division of Digestive Diseases: collaborator
• Carnegie Mellon University: collaborator

Study Sites (2)

UCLA Health Department of Medicine, Quality Office

Westwood, Los Angeles, California, 90095, United States

Location

UCLA Vatche and Tamar Manoukian Division of Digestive Diseases

Westwood, Los Angeles, California, 90095, United States

Location

MeSH Terms

Conditions

Colorectal Neoplasms

Condition Hierarchy (Ancestors)

Intestinal Neoplasms; Gastrointestinal Neoplasms; Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Digestive System Diseases; Gastrointestinal Diseases; Colonic Diseases; Intestinal Diseases; Rectal Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Medical Director, DOM Quality

Model Details: Parallel Assignment * Parallel-arm randomized controlled trial, * Three arms * Arm 0: Standard of care control (standard text messaging) * Arm 1: Experimental, "Risk Information" group * Arm 2: Experimental, "Risk Information + Action" group * Patient-level randomization stratified by arm assignment in CRC45+ Choice Evaluation. The investigators will also randomly assign patients into receiving the text message on one of ten workdays, stratifying by arm assignment in both the CRC45+ Choice Evaluation and CRC45+ Text Evaluation

Study Record Dates

• First Submitted: February 27, 2022
• First Posted: March 16, 2022
• Study Start: February 21, 2022
• Primary Completion: August 21, 2022
• Study Completion: November 21, 2022
• Last Updated: November 13, 2023

Record last verified: 2023-11

Locations

US (2)