Effect of Disseminated Intravascular Coagulation (DIC) Score Changes on Organ Dysfunction in Septic Shock Patients
Sponsor study identifier
observational
60
1 country
1
Study Start
April 12, 2024
Actual (reported)Primary Completion
August 25, 2025
Actual (reported)Study Completion
August 25, 2025
Actual (reported)Septic shock is common complication in patients with critical illnesses, with higher incidence in low and medium income countries like ours. Disseminated intravascular coagulation (DIC) is also common in patients presenting to intensive care units. Further DIC is common coexisting condition seen in many patients presenting with sepsis and septic shock. Both DIC and septic shock individually are associated with very high mortality and morbidity and coexistence of both increase risk manifold. Organ dysfunction is a complication of both septic shock and DIC individually and in presence of coexistence risk further multiply. DIC scoring of every patient at risk as in patients presenting with septic shock help us to predict about patients having more chances to convert to overt DIC. Understanding effects of DIC on organ dysfunction in septic shock patients can help to prognosticate and guide towards early intervention. Also, there is paucity of literature on effect of DIC score changes on organ dysfunction in patients with septic shock.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
August 25, 2025
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
April 9, 2024
Actual (reported)April 12, 2024
Actual (reported)April 12, 2024
Actual (reported)August 25, 2025
Actual (reported)August 25, 2025
Actual (reported)Effect of Disseminated Intravascular Coagulation score changes on organ dysfunction in septic shock patients at day 7
Correlation of Disseminated Intravascular Coagulation score (0 to 8, where higher score is severe) and its change with the organ dysfunction measured as Sequential Organ Failure Assessment score (0 to 24, where higher score has worse outcome)
At day 7 after inclusion
Effect of Disseminated Intravascular Coagulation score changes on organ dysfunction in septic shock patients at day 14
At day 14 after inclusion
Adult ICU patients having septic shock as defined by Sepsis -3 definition requiring vasopressor for at least 12 hours duration will be considered for inclusion in this observational study..
Adult ICU patients having septic shock as defined by Sepsis -3 definition requiring vasopressor for at least 12 hours duration will be considered.
Sanjay Gandhi Postgraduate Institute of Medical Sciences
Lucknow, Uttar Pradesh, 226014, India
Mohan Gurjar, MD, PDCC
Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS)
Dinesh Chandra, MD, DM
Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS)
60 participants (actual enrollment reported by the registry).
First Submitted
April 9, 2024
First Posted
April 12, 2024
Study Start
April 12, 2024
Actual (reported)Study the Impact of Statins in Septic Shock
Contact the study team to confirm eligibility.
Primary Completion
August 25, 2025
Actual (reported)Study Completion
August 25, 2025
Actual (reported)Last Updated
July 28, 2026
Record last verified: 2026-07
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