NCT06358989

Brief Summary

The aim of the present study was to investigate the correlation between the triglyceride/glucose index (TyG index) and homeostasic model assessment of insulin resistance (HOMA-IR) to predict insulin resistance (IR) in obese adults

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Apr 2024

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2024

Completed
5 days until next milestone

First Submitted

Initial submission to the registry

April 6, 2024

Completed
5 days until next milestone

First Posted

Study publicly available on registry

April 11, 2024

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2025

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2025

Completed
Last Updated

April 11, 2024

Status Verified

April 1, 2024

Enrollment Period

1 year

First QC Date

April 6, 2024

Last Update Submit

April 6, 2024

Conditions

Insulin Resistance

Outcome Measures

Primary Outcomes (1)

  • Association between triglycerides glucose ratio with HOMA -IR as indicators of insulin resistance in obese adults

    The study is to investigate the usability of the Ty-G index as an indicator of insulin resistance in obese adults according to its correlation with HOMA-IR

    Baseline

Interventions

HOMA IROTHER

Homa ir

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Any obese adult (18 years or older) with BMI greater than or equal 30 of both sexes admitted to assiut unversity hospitals and clinics

You may qualify if:

  • Any obese adult (18 years or older) with BMI greater than or equal 30 of both sexes admitted to assiut unversity hospitals and clinics

You may not qualify if:

  • Cases \<18 years old
  • Cases with BMI \< 30
  • Adult with endocrine abnormatilies under treatment for DM ,hypertension , dyslipidemia

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (2)

  • Ogden CL, Carroll MD, Curtin LR, McDowell MA, Tabak CJ, Flegal KM. Prevalence of overweight and obesity in the United States, 1999-2004. JAMA. 2006 Apr 5;295(13):1549-55. doi: 10.1001/jama.295.13.1549.

    PMID: 16595758BACKGROUND

  • Bittner V, Johnson BD, Zineh I, Rogers WJ, Vido D, Marroquin OC, Bairey-Merz CN, Sopko G. The triglyceride/high-density lipoprotein cholesterol ratio predicts all-cause mortality in women with suspected myocardial ischemia: a report from the Women's Ischemia Syndrome Evaluation (WISE). Am Heart J. 2009 Mar;157(3):548-55. doi: 10.1016/j.ahj.2008.11.014.

    PMID: 19249427BACKGROUND

MeSH Terms

Conditions

Insulin Resistance

Condition Hierarchy (Ancestors)

HyperinsulinismGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic Diseases

Central Study Contacts

Ayat Esmat

CONTACT

01061135187Ayatesmat55@gmail.com

Hanan Omar, Professor

CONTACT

01223971654Hananomar1962@gmail.com

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Resident doctor

Study Record Dates

First Submitted

April 6, 2024

First Posted

April 11, 2024

Study Start

April 1, 2024

Primary Completion

April 1, 2025

Study Completion

May 1, 2025

Last Updated

April 11, 2024

Record last verified: 2024-04