Effect of Whole-body Vibration on Insulin Resistance in Obese Postmenopausal Women.

NCT05961020 | Completed

• 1 other identifier: p.t.REC\012\004551
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

This study will be conducted to investigate the Effect of whole-body vibration on insulin resistance in obese postmenopausal women

Conditions

Insulin Resistance

Outcome Measures

Primary Outcomes (4)

• The Homeostatic model assessment (The HOMA-IR).

  The Homeostatic model assessment (The HOMA-IR). A sample of 5ml of venous blood sample was drawn from all women after 12 hours fasting for measurement of fasting blood glucose, fasting blood insulin and then detection of insulin resistance (by HOMA -IR) through the equation: HOMA-IR=(Glucose ×Insulin)/405 glucose in mass unit (mg/dl)

  up to 3 months

• BMI

  Weight and height were measured to detect the BMI according to the following equation: BMI= weight/height² (Kg/m²)

  up to 3 months

• Waist circumference

  A non-stretchable tape measurement was used to measure waist circumference for all women in both groups A and B: mid-way between upper border of the lateral iliac crest and the lower border of the lowest rib at the end of gentle expiration with arm relaxed at sides.

  up to 3 months

• Skin fold thickness

  Skin fold caliper was used to measure skin fold thickness at abdominal region for all women in both groups A and B

  up to 3 months

Study Arms (2)

20 women was treated by moderate restricted diet for 3 months.

EXPERIMENTAL

Other: moderate restricted diet

20 women treated by whole body vibration.

EXPERIMENTAL

Device: Total body vibration

Interventions

Total body vibration DEVICE

Whole-body vibration (WBV) training has been established as a useful method to improve physical fitness in obese individuals. Vibration stimulus during half squatting might suggest a long-term effect of WBV on the endocrine system

20 women treated by whole body vibration.

moderate restricted diet OTHER

moderate restricted diet

20 women was treated by moderate restricted diet for 3 months.

Eligibility Criteria

• Age: 50 Years - 60 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• All women were postmenopausal with no menses at least 1 year.
• Their ages were ranged from 50-60 years old.
• Their body mass index (BMI) \> 30 kg/m2.
• They were not engaged in any other treatment program.

You may not qualify if:

• Women with body mass index (BMI) \< 30 kg/m2.
• Any cardio-respiratory diseases.
• Diabetes mellitus.
• with malignancy.
• with severe hemorrhage, acute viral disease and mental disorders.
• Smokers.
• Women with life threatening disorders as renal failure

Sponsors & Collaborators

• October 6 University: lead

Study Sites (1)

Kerolous Ishak Shehata kelini

Cairo, Egypt

Location

MeSH Terms

Conditions

Insulin Resistance

Condition Hierarchy (Ancestors)

Hyperinsulinism; Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: principle investigator

Study Record Dates

• First Submitted: July 6, 2023
• First Posted: July 27, 2023
• Study Start: November 5, 2022
• Primary Completion: January 3, 2023
• Study Completion: July 8, 2023
• Last Updated: May 17, 2024

Record last verified: 2024-05

Locations

EG (1)