NCT06354413

Brief Summary

To investigate clinical characteristics and survival outcomes of patients with obstructive hypertrophic cardiomyopathy who underwent concomitant coronary artery bypass grafting during septal myectomy.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
320

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2009

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2009

Completed
11.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2020

Completed
3 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2023

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

April 2, 2024

Completed
7 days until next milestone

First Posted

Study publicly available on registry

April 9, 2024

Completed
Last Updated

April 9, 2024

Status Verified

April 1, 2024

Enrollment Period

11.9 years

First QC Date

April 2, 2024

Last Update Submit

April 5, 2024

Conditions

Hypertrophic CardiomyopathyCoronary Artery DiseaseMyocardial Bridging

Outcome Measures

Primary Outcomes (1)

  • all-cause mortality

    death because of any reason

    through study completion, an average of 5 year

Secondary Outcomes (1)

  • cardiac-related deaths and readmission

    through study completion, an average of 5 year

Interventions

CABG during myectomyPROCEDURE

To explore the effect of CABG during myectomy. No control group

Eligibility Criteria

Age8 Years - 90 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

patients with obstructive hypertrophic cardiomyopathy who underwent concomitant coronary artery bypass grafting(due to atherosclerosis coronary artery diseases or myocardial bridge) during septal myectomy.

You may qualify if:

  • Clinical diagnosis of obstructive hypertrophic cardiomyopathy.
  • Undergo ventricular septal resection and cardiac bypass surgery at the same time.

You may not qualify if:

  • Incomplete surgical and follow-up data

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Cardiomyopathy, HypertrophicCoronary Artery DiseaseMyocardial Bridging

Condition Hierarchy (Ancestors)

CardiomyopathiesHeart DiseasesCardiovascular DiseasesAortic Stenosis, SubvalvularAortic Valve StenosisAortic Valve DiseaseHeart Valve DiseasesCoronary DiseaseMyocardial IschemiaArteriosclerosisArterial Occlusive DiseasesVascular DiseasesCoronary Vessel AnomaliesHeart Defects, CongenitalCardiovascular AbnormalitiesCongenital AbnormalitiesCongenital, Hereditary, and Neonatal Diseases and Abnormalities

Study Officials

  • Tao Lu, MD

    Chinese Academy of Medical Sciences, Fuwai Hospital

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dr.

Study Record Dates

First Submitted

April 2, 2024

First Posted

April 9, 2024

Study Start

January 1, 2009

Primary Completion

December 1, 2020

Study Completion

December 1, 2023

Last Updated

April 9, 2024

Record last verified: 2024-04

Data Sharing

IPD Sharing
Will not share