NCT00928356

Brief Summary

The primary objective of this study is to assess the safety and effectiveness of same sitting, simultaneous hybrid robotic assisted coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI) in the treatment of obstructive multivessel coronary artery disease. A secondary objective is the assessment and standardization of optimal operator techniques and comparative study of patients undergoing CABG during study period.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
88

participants targeted

Target at P25-P50 for not_applicable coronary-artery-disease

Timeline
Completed

Started Oct 2008

Longer than P75 for not_applicable coronary-artery-disease

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 14, 2008

Completed
8 months until next milestone

First Submitted

Initial submission to the registry

June 23, 2009

Completed
2 days until next milestone

First Posted

Study publicly available on registry

June 25, 2009

Completed
5.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 19, 2015

Completed
4.2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

August 13, 2019

Completed
Last Updated

May 11, 2020

Status Verified

March 1, 2019

Enrollment Period

6.6 years

First QC Date

June 23, 2009

Last Update Submit

May 7, 2020

Conditions

Keywords

Coronary Artery DiseaseRobotic Coronary Artery Bypass SurgeryPercutaneous Coronary InterventionHybrid Coronary Revascularization

Outcome Measures

Primary Outcomes (1)

  • The primary endpoint of this feasibility study is a 30-day composite of major adverse clinical events including death, repeat revascularization, stroke and/or myocardial infarction.

    1 year

Secondary Outcomes (1)

  • One-year composite clinical event endpoints of major clinical events. Comparative analysis of consecutive patients undergoing off pump CABG with standard thoracotomy during study period.

    1 year

Study Arms (2)

Hybrid CABG/PCI

EXPERIMENTAL

Patients undergo hybrid, same sitting CABG/PCI as described.

Procedure: Hybrid CABG/PCI

Off-pump CABG

OTHER

Standard of Care Off Pump CABG

Procedure: Off Pump CABG

Interventions

Same sitting hybrid, robotic CABG/PCI

Hybrid CABG/PCI
Off Pump CABGPROCEDURE

Standard of Care Off Pump CABG

Off-pump CABG

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Requirement for CABG
  • Anatomy and body habitus suitable for Robotic CABG
  • Requirement of revascularization of arteries amendable for PCI but not accessable by Robotic CABG

You may not qualify if:

  • Need for emergent CABG

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

UPMC Pinnacle Harrisburg

Harrisburg, Pennsylvania, 17011, United States

Location

Related Links

MeSH Terms

Conditions

Coronary Artery Disease

Condition Hierarchy (Ancestors)

Coronary DiseaseMyocardial IschemiaHeart DiseasesCardiovascular DiseasesArteriosclerosisArterial Occlusive DiseasesVascular Diseases

Study Officials

  • William Bachinsky, M.D.

    Pinnacle Health Cardiovascular Institute, Inc.

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
NETWORK
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 23, 2009

First Posted

June 25, 2009

Study Start

October 14, 2008

Primary Completion

May 19, 2015

Study Completion

August 13, 2019

Last Updated

May 11, 2020

Record last verified: 2019-03

Data Sharing

IPD Sharing
Will not share

Locations