CT-based Model for Predicting Prolonged Weaning in Patients With Abdominal Trauma

NCT06339073 | Completed

• 1 other identifier: 2021NZKY-045-01
• Study Type: observational
• Target: 1,023
• Locations: 1 country
• Sites: 1

Brief Summary

Critically ill patients often require tracheal intubation for mechanical ventilation, and timely weaning is crucial for airway management and reducing complications. However, there is currently a lack of an effective tool to predict weaning time in critically ill patients. This retrospective study established an effective nomogram model for predicting the time of weaning from mechanical ventilation in abdominal trauma patients by considering multiple perspectives. The model has been validated and demonstrated good performance in terms of discrimination, calibration, and clinical utility. Moreover, the model can effectively predict the prognosis of critically ill patients. The findings of this study have important implications for guiding respiratory management in clinically critically ill patients, particularly trauma patients.

Conditions

Wounds and Injuries; Ventilation Therapy; Complications

Keywords

computed tomography; prolonged weaning; ventilation; trauma

Outcome Measures

Primary Outcomes (1)

• Prolonged mechanical ventilation

  Prolonged mechanical ventilation was defined as length of mechanical ventilation \>7 days

  through whole hospitalization of each participant, an average of 25 days

Interventions

mechanical ventilation DEVICE

Abdominal trauma patients were treated with mechanical ventilation according to their conditions.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with abdominal trauma admitted to the General Surgical Department of Jinling Hospital from January 2010 to April 2023 were screened for eligibility.

You may qualify if:

• (1) with information on survival status and time;
• (2) aged 18-80 years;
• (3) admitted to ICU;
• (4) with abdominal CT performed within 1-week post-trauma;
• (5) use of mechanical ventilation.

You may not qualify if:

• (1) low-quality CT images;
• (2) history of mental illness.

Sponsors & Collaborators

• Jinling Hospital, China: lead

Study Sites (1)

the General Surgical Department of Jinling Hospital

Nanjing, Jiangsu, 210002, China

Location

MeSH Terms

Conditions

Wounds and Injuries; Respiratory Aspiration

Interventions

Respiration, Artificial

Condition Hierarchy (Ancestors)

Respiration Disorders; Respiratory Tract Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Airway Management; Therapeutics; Resuscitation; Emergency Treatment; Respiratory Therapy

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Chief of the Department of Intensive Care Unit, Associate chiefphysician

Study Record Dates

• First Submitted: March 24, 2024
• First Posted: April 1, 2024
• Study Start: October 1, 2023
• Primary Completion: December 15, 2023
• Study Completion: February 5, 2024
• Last Updated: April 1, 2024

Record last verified: 2024-03

Locations

CN (1)