Outcome and Predictors of Mortality of Patients on Prolonged Mechanical Ventilation

NCT06087939 | Not Yet Recruiting

• 1 other identifier: PMV
• Study Type: observational
• Target: 323
• Locations: 0 countries
• Sites: N/A

Brief Summary

Prolonged mechanical ventilation (PMV) and weaning failure are factors associated with prolonged hospital length of stay and increased morbidity and mortality. In addition to the individual challenges that stress patients and their families, the resource-intensive care these patients receive places a significant burden on the public health system. These burdens often persist over the long term, especially in the case of weaning failure with subsequent home mechanical ventilation (HMV). This study will provide invaluable and in-depth knowledge of major sources of admission to ICU and will clarify the cause for the outcomes seen after prolonged mechanical ventilation in ICU admission, at Dessie comprehensive Hospital, the result of our study will also serve as a source or baseline information for future valuable researches to be undergone around the subject of interest.

Conditions

Outcome

Outcome Measures

Primary Outcomes (1)

• clinical outcomes of critically ill patients undergoing prolonged mechanical ventilation

  Clinical outcome: indicated either patient survived or died at the time of discharge. Prolonged mechanical ventilation: is defined as successful extubation after more than three spontaneous breathing trials or taking more than 14 days

  5 months

Interventions

Mechanical ventilation DEVICE

Mechanical ventilation (MV) is a life support technique that is routinely used in the intensive care units (ICUs) for patients with life-threatening conditions.

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All charts of critically ill patients admitted to ICU of Dessie comprehensive specialized hospital.

You may qualify if:

• All charts of critically ill patients on prolonged mechanical ventilation in of Dessie Comprehensive Specialized Hospital during the study period.

You may not qualify if:

• Charts with incomplete information and missing values as well as those that are not available will be excluded from the study.

Sponsors & Collaborators

• Wollo University: lead

MeSH Terms

Interventions

Respiration, Artificial

Intervention Hierarchy (Ancestors)

Airway Management; Therapeutics; Resuscitation; Emergency Treatment; Respiratory Therapy

Central Study Contacts

Sara Timerga

CONTACT

+251925044807; sara24tn@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer

Study Record Dates

• First Submitted: September 29, 2023
• First Posted: October 18, 2023
• Study Start: July 15, 2024
• Primary Completion: August 30, 2024
• Study Completion: August 30, 2024
• Last Updated: April 30, 2024

Record last verified: 2024-04

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP, ICF, CSR, ANALYTIC CODE
• Time Frame: The data will be available with 5 month time.