Effect of Slope Time in PCV Mode on Mechanical Power Calculation and Oxygenation in Covid-19 ARDS Patients.
Retrospective Evaluation of the Effect of Slope Time in PCV Mode on Mechanical Power Calculation and Oxygenation in Covid-19 ARDS Patients.
1 other identifier
observational
40
1 country
1
Brief Summary
The investigators are planning to investigate the effect of each 5% slope time change on mechanical power and SPO2 of the patients with Covid 19 ARDS diagnosis which are on mechanical ventilation PCV mode support.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Jun 2022
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
June 6, 2022
CompletedFirst Submitted
Initial submission to the registry
July 25, 2022
CompletedFirst Posted
Study publicly available on registry
July 26, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 6, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
August 30, 2022
CompletedAugust 3, 2022
August 1, 2022
2 months
July 25, 2022
August 1, 2022
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
mechanical power
Mechanical power calculated by Becher et al. comprehensive formula (MPpcv(slope)) and Trinkle, Christine A et al lineer model mechanical power formula (MPLM).
100 minutes
Study Arms (1)
Covid-19 ARDS patients on PCV mode
No Intervention
Interventions
Pressure controlled ventilation mode on mechanical ventilation
Eligibility Criteria
Adult patients with Covid-19 ARDS diagnosis which has been admitted to intensive care unit, intubated and are on PCV mode on mechanical ventilation support will be included in the study.
You may qualify if:
- adult patients with Covid-19 Acute Respiratory Distress Syndrome (ARDS) diagnosis
- intubated Covid-19 ARDS patients
- Covid-19 ARDS patients on mechanical ventilator support
You may not qualify if:
- heart failure disease
- Chronic Obstructive Pulmonary Disease (COPD)
- hemodynamically unstable patients
- pregnancy
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Bakırköy Dr sadi konuk Education hospital
Istanbul, Turkey (Türkiye)
Related Publications (2)
Becher T, van der Staay M. Calculation of mechanical power for pressure-controlled ventilation: author's reply. Intensive Care Med. 2019 Oct;45(10):1498-1499. doi: 10.1007/s00134-019-05742-7. Epub 2019 Aug 20. No abstract available.
PMID: 31432217BACKGROUNDTrinkle CA, Broaddus RN, Sturgill JL, Waters CM, Morris PE. Simple, accurate calculation of mechanical power in pressure controlled ventilation (PCV). Intensive Care Med Exp. 2022 May 30;10(1):22. doi: 10.1186/s40635-022-00448-5.
PMID: 35644896RESULT
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
sinan asar, M.D
intensive care supspecialist
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER GOV
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
July 25, 2022
First Posted
July 26, 2022
Study Start
June 6, 2022
Primary Completion
August 6, 2022
Study Completion
August 30, 2022
Last Updated
August 3, 2022
Record last verified: 2022-08