NCT06333704

Brief Summary

The main objective of the surveillance is to evaluate the incidence of the adverse events (AEs), and other safety-related information in South-Korean population.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
4,207

participants targeted

Target at P75+ for all trials

Timeline
36mo left

Started Mar 2023

Longer than P75 for all trials

Geographic Reach
1 country

26 active sites

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress51%
Mar 2023Mar 2029

Study Start

First participant enrolled

March 10, 2023

Completed
1 year until next milestone

First Submitted

Initial submission to the registry

March 20, 2024

Completed
7 days until next milestone

First Posted

Study publicly available on registry

March 27, 2024

Completed
5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 29, 2029

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 29, 2029

Last Updated

April 16, 2026

Status Verified

April 1, 2026

Enrollment Period

6.1 years

First QC Date

March 20, 2024

Last Update Submit

April 13, 2026

Conditions

Keywords

mRNA-1273mRNA-1273 vaccineSARS-CoV-2SARS-CoV-2 VaccineCoronavirusVirus DiseasesMessenger RNACOVID-19COVID-19 VaccineModerna

Outcome Measures

Primary Outcomes (1)

  • Number of Participants With AEs

    Up to 28 days post vaccination

Study Arms (1)

SPIKEVAX BIVALENT, SPIKEVAX X, SPIKEVAX JN, or SPIKEVAX IN PRE-FILLED SYRINGE

Participants receiving at least 1 dose of SPIKEVAX BIVALENT vaccine, SPIKEVAX X Injection, SPIKEVAX JN Injection, or SPIKEVAX in Pre-filled Syringe will be monitored for safety parameters up to 28 days post vaccination.

Biological: SPIKEVAX Bivalent BA.1Biological: SPIKEVAX Bivalent BA.4/5Biological: SPIKEVAX XBB.1.5Biological: SPIKEVAX JN.1

Interventions

No study drug will be administered during this study as this is an observational study.

Also known as: MODERNA SPIKEVAX BIVALENT (Elasomeran, Imelasomeran), SPIKEVAX BIVALENT (Elasomeran, Imelasomeran)
SPIKEVAX BIVALENT, SPIKEVAX X, SPIKEVAX JN, or SPIKEVAX IN PRE-FILLED SYRINGE

No study drug will be administered during this study as this is an observational study.

Also known as: SPIKEVAX BIVALENT (Elasomeran, Davesomeran), SPIKEVAX BIVALENT INJECTION DUO (Elasomeran, Davesomeran)
SPIKEVAX BIVALENT, SPIKEVAX X, SPIKEVAX JN, or SPIKEVAX IN PRE-FILLED SYRINGE

No study drug will be administered during this study as this is an observational study.

Also known as: SPIKEVAX X Injection
SPIKEVAX BIVALENT, SPIKEVAX X, SPIKEVAX JN, or SPIKEVAX IN PRE-FILLED SYRINGE
SPIKEVAX JN.1BIOLOGICAL

No study drug will be administered during this study as this is an observational study.

Also known as: SPIKEVAX JN Injection, SPIKEVAX in Pre-filled Syringe
SPIKEVAX BIVALENT, SPIKEVAX X, SPIKEVAX JN, or SPIKEVAX IN PRE-FILLED SYRINGE

Eligibility Criteria

Age12 Years+
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

The population of this survey is Korean participants vaccinated with SPIKEVAX BIVALENT BA.1, SPIKEVAX BIVALENT BA.4/5, SPIKEVAX XBB.1.5, and SPIKEVAX JN.1 who meet the inclusion/exclusion criteria.

You may qualify if:

  • Participants should be 18 years or older for SPIKEVAX BIVALENT BA.1, SPIKEVAX BIVALENT BA.4/5, and 12 years or older for SPIKEVAX XBB.1.5 and SPIKEVAX JN.1.
  • Participants of any age which is approved for the use of SPIKEVAX BIVALENT BA.1, SPIKEVAX BIVALENT BA.4/5, SPIKEVAX XBB.1.5, or SPIKEVAX JN.1 for active immunization to prevent COVID-19 caused by SARS-CoV-2.
  • Participant who will be vaccinated with SPIKEVAX BIVALENT BA.1, SPIKEVAX BIVALENT BA.4/5, SPIKEVAX XBB.1.5, or SPIKEVAX JN.1 following local label approved by Ministry of Food and Drug Safety (MFDS).
  • Participant who will be vaccinated with at least one dose of SPIKEVAX BIVALENT BA.1, SPIKEVAX BIVALENT BA.4/5, SPIKEVAX XBB.1.5, or SPIKEVAX JN.1.

You may not qualify if:

  • Participant whose participation is deemed inappropriate at the investigator's discretion.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (26)

Yonseimin Clinic

Wŏnju, Gangwon-do, 26428, South Korea

Location

Hyundai Clinic

Bucheon-si, Gyeonggi-do, 14483, South Korea

Location

Ma Hak ki Family Medicine Clinic

Bucheon-si, Gyeonggi-do, 14614, South Korea

Location

Nalee Hospital

Gimpo-si, Gyeonggi-do, 10108, South Korea

Location

COA ENT Clinic

Goyang-si, Gyeonggi-do, 10234, South Korea

Location

Joon Pediatric Clinic

Gwangmyeong, Gyeonggi-do, 14250, South Korea

Location

Janghyeon Medicine Clinic

Namyangju, Gyeonggi-do, 14998, South Korea

Location

Jeong's Family Medical Clinic

Siheung, Gyeonggi-do, 15065, South Korea

Location

Hanyang Union Rehabilitation Medicine Clinic

Yangju, Gyeonggi-do, 11404, South Korea

Location

KimHyungjoo Clinic

Yangju, Gyeonggi-do, 11456, South Korea

Location

Kium Children Hospital

Gunsan, Jeollabuk-do, 54072, South Korea

Location

Sinsegie ENT Clinic

Busan, 48111, South Korea

Location

Bupyeong Yonsei Medical Clinic

Incheon, 21405, South Korea

Location

Inha University Hospital

Incheon, 22332, South Korea

Location

Woori Medical Clinic

Seoul, 01684, South Korea

Location

Yonsei Kids Pediatrics Clinic

Seoul, 01851, South Korea

Location

Star Pediatrics Clinic

Seoul, 03912, South Korea

Location

Seoul Bon Clinic

Seoul, 04032, South Korea

Location

Dr Cho's Family Medical Clinic

Seoul, 05351, South Korea

Location

Songpa Korea Neurosurgical Clinic

Seoul, 05769, South Korea

Location

GF Pediatrics Clinic

Seoul, 06568, South Korea

Location

Kim Il Joong Internal Medicine Clinic

Seoul, 06727, South Korea

Location

New Yonsei ENT Clinic

Seoul, 07327, South Korea

Location

Gangseo HANA ENT

Seoul, 07774, South Korea

Location

Kim's Pediatrics Clinic

Seoul, 08652, South Korea

Location

Soo Orthopedics Clinic

Seoul, 08701, South Korea

Location

MeSH Terms

Conditions

Coronavirus InfectionsVirus DiseasesCOVID-19

Interventions

2019-nCoV Vaccine mRNA-1273

Condition Hierarchy (Ancestors)

Coronaviridae InfectionsNidovirales InfectionsRNA Virus InfectionsInfectionsPneumonia, ViralPneumoniaRespiratory Tract InfectionsLung DiseasesRespiratory Tract Diseases

Intervention Hierarchy (Ancestors)

mRNA VaccinesNucleic Acid-Based VaccinesVaccines, SyntheticRecombinant ProteinsProteinsAmino Acids, Peptides, and ProteinsVaccinesBiological ProductsComplex MixturesCOVID-19 VaccinesViral VaccinesAntigensBiological Factors

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 20, 2024

First Posted

March 27, 2024

Study Start

March 10, 2023

Primary Completion (Estimated)

March 29, 2029

Study Completion (Estimated)

March 29, 2029

Last Updated

April 16, 2026

Record last verified: 2026-04

Locations