Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 35/100

Failure Rate

8.6%

12 terminated/withdrawn out of 139 trials

Success Rate

87.5%

+1.0% vs industry average

Late-Stage Pipeline

20%

28 trials in Phase 3/4

Results Transparency

45%

38 of 84 completed trials have results

Key Signals

19 recruiting38 with results8 terminated4 withdrawn

Enrollment Performance

Analytics

Phase 1
59(50.9%)
Phase 2
27(23.3%)
Phase 3
23(19.8%)
Phase 4
5(4.3%)
N/A
1(0.9%)
Early Phase 1
1(0.9%)
116Total
Phase 1(59)
Phase 2(27)
Phase 3(23)
Phase 4(5)
+2 more

Activity Timeline

Global Presence

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Clinical Trials (139)

Showing 20 of 139 trials
NCT06077760Phase 3Recruiting

A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)

Role: collaborator

NCT06623422Phase 3Recruiting

A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)

Role: collaborator

NCT07513376Phase 3Recruiting

A Clinical Trial of Adjuvant Intismeran (V940) With or Without Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) in High-Risk Stage I Non-Small Cell Lung Cancer (V940-014)

Role: collaborator

NCT07737717Phase 1Not Yet Recruiting

A Study to Investigate the Safety, Reactogenicity, and Immunogenicity of mRNA-1469 Vaccine to Prevent Ebola-Bundibugyo Virus Disease in Healthy Adult Participants

Role: lead

NCT05975099Phase 1Completed

A Study to Evaluate the Safety and Immunogenicity of mRNA-1975 and mRNA-1982 Against Lyme Disease in Participants 18 Through 70 Years of Age

Role: lead

NCT07116616Phase 1Recruiting

A Study of mRNA-2808 in Participants With Relapsed or Refractory Multiple Myeloma

Role: lead

NCT05533697Phase 1Recruiting

Study of mRNA-4359 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Advanced Solid Tumors

Role: lead

NCT06307431Phase 2Active Not Recruiting

A Study of Adjuvant Intismeran Autogene (V940) and Pembrolizumab in Renal Cell Carcinoma (V940-004).

Role: collaborator

NCT07221474Phase 2Recruiting

A Study of Intismeran Autogene (V940)/Placebo + Pembrolizumab and Chemotherapy in Metastatic Squamous Non-Small Cell Lung Cancer (V940-013)

Role: collaborator

NCT07089706Phase 4Completed

A Study to Evaluate the Immunogenicity and Safety of mRNA-1283 COVID-19 Variant-containing Formulations

Role: lead

NCT06833073Phase 2Recruiting

A Clinical Study of Intismeran Autogene (V940) and BCG in People With Bladder Cancer (V940-011/INTerpath-011)

Role: collaborator

NCT06694753Phase 1Active Not Recruiting

Safety and Immunogenicity Study of Three mRNAs Encoding HIV Immunogens in Adult Participants Without HIV and in Overall Good Health in South Africa.

Role: collaborator

NCT05743881Phase 1Active Not Recruiting

A Safety, Tolerability, and Immunogenicity Study of mRNA-1345 and mRNA-1365 in Participants Aged 5 Months to <24 Months

Role: lead

NCT06735248Phase 2Recruiting

A Study to Investigate Multiple Sclerosis Relapse Prevention With mRNA-1195 Compared With Placebo in Participants Aged 18 to ≤55 Years

Role: lead

NCT06143046Phase 2Completed

A Study of mRNA-1345 Vaccine Targeting Respiratory Syncytial Virus in Pregnant Women and in Infants Born to Vaccinated Mothers

Role: lead

NCT05575492Phase 1Completed

A Study of mRNA-1647 Cytomegalovirus Vaccine in Healthy Participants 9 to 15 Years of Age and Participants 16 to 25 Years of Age

Role: lead

NCT07561294Phase 2Recruiting

A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1982 to Prevent Lyme Disease in Healthy Participants (18 to 70 Years of Age)

Role: lead

NCT06880549Phase 1Active Not Recruiting

A Study of mRNA-4106 or mRNA-4200 Administered Alone or in Combination With Anti-Cancer Agents in Participants With Solid Tumors

Role: lead

NCT05683457Phase 2Active Not Recruiting

A Study to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1647 Cytomegalovirus (CMV) Vaccine in Allogenic Hematopoietic Cell Transplantation (HCT) Participants.

Role: lead

NCT05831787Completed

COVID19 OutcomeS in Myeloma and the Impact of VaCcines

Role: collaborator