The IMPACT Implementation-Effectiveness Trial
IMPACT
Implementing Physical Activity for Individuals With Cancer During Treatment: The IMPACT Implementation-Effectiveness Trial
1 other identifier
interventional
129
1 country
3
Brief Summary
More Canadians are surviving cancer, however, individuals with cancer live with side effects for years after treatments have ended. The physical and psychosocial benefits of regular physical activity (PA) during and after cancer treatment are well established. However, less than 30% of individuals with cancer meet current PA recommendations and PA levels decline significantly during treatment. PA services within the cancer institution to support well-being during treatment are not available for survivors across Ontario. Strategies are needed within cancer centres to close the gap between the evidence and clinical practice. What is the purpose? To evaluate the effectiveness of a novel exercise and education strategy for individuals with cancer during treatment. What are we proposing to do? This project includes two parts. In Part 1 participants will be put into one of three groups. Group 1 (Exercise \& self-management) will include eight sessions of supervised, institution-based exercise and self-management education. Group 2 (self-management only) will include eight virtual self-management education sessions with an exercise professional. Group 3 will receive usual care (i.e., no intervention). In Part 2 participants who attended less than 75% of their sessions will be asked to complete an interview on the barriers to continuing with the study during cancer treatment. Why is this work important? Findings from this trial will inform the way PA services are provided within cancer institutions across Ontario. This novel strategy incorporates both institution-based and home-based exercise strategies during treatment and highlights the importance of individuals with cancer taking an active role in managing their condition during treatment. This can prevent future complications and decrease burden on the individual and the healthcare system. Results will inform future decisions on PA implementation strategies for cancer survivors with diverse needs across Ontario.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for phase_2 cancer
Started Mar 2024
3 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
March 6, 2024
CompletedStudy Start
First participant enrolled
March 15, 2024
CompletedFirst Posted
Study publicly available on registry
March 21, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 15, 2027
ExpectedStudy Completion
Last participant's last visit for all outcomes
March 15, 2027
March 12, 2025
March 1, 2025
3 years
March 6, 2024
March 10, 2025
Conditions
Outcome Measures
Primary Outcomes (3)
Physical activity level
Godin Leisure Time Exercise Questionnaire
16-weeks
Physical activity level
Godin Leisure Time Exercise Questionnaire
12-months
Physical activity level
Godin Leisure Time Exercise Questionnaire
6-months
Secondary Outcomes (18)
Quality of life
16-weeks
Quality of life
6-months
Quality of life
12-months
Level of exercise knowledge
16-weeks
Level of exercise knowledge
6-months
- +13 more secondary outcomes
Study Arms (3)
Exercise & Self-Management
EXPERIMENTALSelf-Management Only
EXPERIMENTALUsual Care
NO INTERVENTIONInterventions
Eight sessions of moderate intensity aerobic exercise using recumbent bike within the cancer institution.
Eight 15 minute self-management e-modules related to exercise and physical activity for cancer survivors.
Eligibility Criteria
You may qualify if:
- adults with a cancer diagnosis (any type or stage)
- individuals are currently receiving treatment for cancer
- individuals have been cleared for exercise by their oncology care team
You may not qualify if:
- \) Self-report any chronic condition, cognitive impairment, or injury that would prevent them from participating in moderate intensity exercise
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- McMaster Universitylead
- Canadian Cancer Society (CCS)collaborator
- Hamilton Health Sciences Corporationcollaborator
- Niagara Health Systemcollaborator
Study Sites (3)
Joseph Brant Hospital
Burlington, Ontario, L7S 0A2, Canada
Juravinski Cancer Centre
Hamilton, Ontario, L8V 5C2, Canada
Walker Family Cancer Centre
St. Catharines, Ontario, L2S 0A9, Canada
Related Publications (1)
Smith-Turchyn J, Sabiston CM, Edward H, Richardson J, Nayiga BK, Page A, Brooks D, Mukherjee SD. Implementing physical activity for individuals with cancer during treatment: protocol for the IMPACT implementation-effectiveness trial. BMJ Open. 2025 Mar 27;15(3):e101013. doi: 10.1136/bmjopen-2025-101013.
PMID: 40148001DERIVED
MeSH Terms
Conditions
Interventions
Intervention Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- phase 2
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- INVESTIGATOR, OUTCOMES ASSESSOR
- Purpose
- SUPPORTIVE CARE
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
March 6, 2024
First Posted
March 21, 2024
Study Start
March 15, 2024
Primary Completion (Estimated)
March 15, 2027
Study Completion (Estimated)
March 15, 2027
Last Updated
March 12, 2025
Record last verified: 2025-03
Data Sharing
- IPD Sharing
- Will not share