Effects of Recursive Self-feedback on Speech Production in Aphasia

NCT06323629 | Not Yet Recruiting

• 1 other identifier: STUDY006201
• Study Type: interventional
• Target: 45
• Locations: 0 countries
• Sites: N/A

Brief Summary

The goal of this clinical trial is to test the effects of recursive self-feedback procedures on spontaneous speech production in stroke survivors with impaired speech production (aphasia). The main question it aims to answer is:

• To what extent can stroke survivors with aphasia use their self-feedback alone to improve their spontaneous speech production? Participants will be engaged in the following activities:
• They will perform language and cognitive tasks.
• Afterwards, they will receive treatments using tablets and headphones at no cost to them.
• The experimental treatments (recursive self-feedback procedures) entails responding to prompts, listening to playbacks of their speech response and attempt to minimize/correct the errors in the next attempt. This process will be repeated multiple times per prompt.
• The experimental treatments are two: an adaptive version that adapts the complexity of the treatment prompt and a non-adaptive version that does not adapt task complexity.
• Researchers will compare the experimental treatments to see if both have similar effects on improving spontaneous speech production.

Conditions

Aphasia; Stroke

Outcome Measures

Primary Outcomes (2)

• Speaking rate

  Correct words produced per minute

  Within 1 week before treatment and within 1 week after treatment.

• Speech initiation latency in milliseconds

  Latency before retrieving the first correct word in an utterance.

  Within 1 week before treatment and within 1 week after treatment.

Study Arms (2)

Adaptive recursive self-feedback procedure

EXPERIMENTAL

Using a tablet, participants listen to speech playback of their response to a prompt and self-correct/minimize their speech errors in a subsequent attempt. This process is looped multiple times per prompt. It adapts across narrative prompts with low and high complexities.

Behavioral: Adaptive recursive self-feedback procedure

Non-adaptive recursive self-feedback procedure

EXPERIMENTAL

Using a tablet, participants listen to speech playback of their response to a prompt and self-correct/minimize their speech errors in a subsequent attempt. This process is looped multiple times per prompt. However, it only uses narrative prompts with high complexity.

Behavioral: Non-adaptive recursive self-feedback procedure

Interventions

Adaptive recursive self-feedback procedure BEHAVIORAL

The intervention uses self-feedback alone to improve speech production. It adapts the complexity of the treatment tasks.

Adaptive recursive self-feedback procedure

Non-adaptive recursive self-feedback procedure BEHAVIORAL

The intervention uses self-feedback alone to improve speech production. However, it does not adapt the complexity of the treatment tasks.

Non-adaptive recursive self-feedback procedure

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• months post left hemisphere stroke
• Aphasia due to left hemisphere stroke
• Dominant English speaker

You may not qualify if:

• Speech-language deficits due to neurological insults such as Parkinson's disease, neurodegenerative conditions etc.
• Uncorrected sensory impairments.
• Language comprehension impairment.
• Severe cognitive impairment.

Sponsors & Collaborators

• University of South Florida: lead
• Center for Smart Use of Technologies to Assess Real-world Outcomes: collaborator

MeSH Terms

Conditions

Aphasia; Stroke

Condition Hierarchy (Ancestors)

Speech Disorders; Language Disorders; Communication Disorders; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Study Officials

• Gerald C. Imaezue, PhD

  University of South Florida

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Gerald C. Imaezue, PhD

CONTACT

(813)974-2464; gimaezue@usf.com

William Burgin, MD

CONTACT

813-259-8577; wburgin@usf.edu

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 21, 2024
• First Posted: March 21, 2024
• Study Start: April 1, 2024
• Primary Completion: March 1, 2025
• Study Completion: March 1, 2025
• Last Updated: March 21, 2024

Record last verified: 2024-03

Data Sharing

• IPD Sharing: Will not share