Postoperative Delirium in the Post-anesthesia Care Unit
Analysis of the Incidence and Influencing Factors of Postoperative Delirium in the Post-anesthesia Care Unit: A Multicenter, Observational, Matched Case-control Study
1 other identifier
observational
3,320
1 country
2
Brief Summary
This study aims to investigate the incidence of postoperative delirium (POD) in the PACU and analyze its influencing factors, in order to provide theoretical basis for early screening and intervention for high-risk POD population. Blood samples of some study subjects will be collected and analyzed using molecular detection methods to provide a basis and insights into the pathophysiological mechanisms of POD.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2024
Shorter than P25 for all trials
2 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 20, 2024
CompletedFirst Submitted
Initial submission to the registry
March 12, 2024
CompletedFirst Posted
Study publicly available on registry
March 19, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 30, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
December 30, 2024
CompletedMarch 19, 2024
March 1, 2024
12 months
March 12, 2024
March 12, 2024
Conditions
Outcome Measures
Primary Outcomes (1)
Postoperative delirium
Mini-Mental State Examination, MMSE
1 Hour
Study Arms (1)
Patients staying in the PACU
Patients staying in the PACU
Interventions
Eligibility Criteria
Patients entering the PACU and meeting the inclusion criteria of this study
You may qualify if:
- Patients voluntarily participating in this study
- Age ≥18 years old
- ASA classification I-IV
- Complete clinical data
You may not qualify if:
- ASA classification V and above
- History of severe central nervous system diseases, psychiatric disorders, cognitive impairment, intellectual disability, or Mini-Mental State Examination (MMSE) score ≤23
- Patients with communication barriers
- Patients with missing clinical data
- Patients with severe complications during PACU observation requiring reintubation, reoperation, or transfer to the intensive care unit for further treatment
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Qin Zhanglead
- National Natural Science Foundation of Chinacollaborator
Study Sites (2)
The First Hospital of Harbin Medical University
Harbin, Heilongjiang, 150000, China
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, 430030, China
Biospecimen
Plasma
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Qin Zhang
Tongji Medical College, Huazhong University of Science and Technology
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- Professor
Study Record Dates
First Submitted
March 12, 2024
First Posted
March 19, 2024
Study Start
January 20, 2024
Primary Completion
December 30, 2024
Study Completion
December 30, 2024
Last Updated
March 19, 2024
Record last verified: 2024-03