Personalized Prevention and Treatment Strategies for Adolescent Idiopathic Scoliosis Via a Comprehensive Health Management Platform

NCT06314594 | Recruiting DMC

• 1 other identifier: 2024KY920
• Study Type: interventional
• Target: 76
• Locations: 1 country
• Sites: 1

Brief Summary

Spinal cord injury (SCI), leads to functional deficits and complications like neurogenic bladder and deep vein thrombosis, imposing a global annual financial burden. This trial aims to compares Jiaji electroacupuncture (JEA) and scalp electroacupuncture (SEA) in SCI rehabilitation. This randomized controlled trial (RCT) compared JEA and SEA in SCI rehabilitation.

Conditions

Adolescent Idiopathic Scoliosis (AIS)

Keywords

spinal cord injury; electroacupuncture; Jiaji acupoint; scalp acupuncture; clinical efficacy

Outcome Measures

Primary Outcomes (3)

• Number of Cobb angles

  X-rays were used to check the number of Cobb angles before and 4 months after the intervention to observe the improvement of scoliosis

  4 months before the intervention and 4 months after the intervention

• Accuracy of new screening modalities

  The new screening method "general examination + forward flexion test + scoliosis measuring instrument" was used for examination, and the data results before and 4 months after intervention were compared with the X-ray examination results to verify its accuracy.

  4 months before and after the intervention, 4 months after the end of the intervention, and 8 months after the end of the intervention

• Hamilton Depression Volume

  Depression status was rated using the Hamilton Depression Rating Scale

  4 months before and after the intervention, 4 months after the end of the intervention, and 8 months after the end of the intervention

Study Arms (2)

control

NO INTERVENTION

Conventional treatment

intervention

EXPERIMENTAL

Using paradigms based on transfer learning and semi-supervised learning, using multiple learning methods, transformer image classification algorithms and other mathematical methods, an early warning model and stepped treatment model for adolescent scoliosis were developed and verified, and a cost-effectiveness analysis was conducted at the same time.

Procedure: Conventional treatment; Behavioral: intervention treatment

Interventions

intervention treatment BEHAVIORAL

Patients will be input into the health management platform. The optimal treatment scheme will be then determined through data calculation and sent to individuals (or their families) or schools for implementation under the guidance of the platform. It is important to note that the specific treatment plan varied from person to person. Patients were observed and intervened for a period of 4 months. 1. Massage therapy 2. Posture guidance 3. Schroeder\'s gymnastics therapy 4. Bioelectric stimulation therapy

intervention

Conventional treatment PROCEDURE

Patients will randomly assigned to routine treatment group (control group) and individualized treatment model group (intervention group). All patients will observed and intervened for 4 months. Patients in the control treatment group will follow the treatment plan in the 2016SOSORT guidelines

intervention

Eligibility Criteria

• Age: 3 Years - 18 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• The diagnosis of moderate and mild AIS, with a Cobb angle measuring less than 45°;
• The age range of 12 to 16 years old;
• Participants are required to have no history of mental illness, possess normal communication skills, and be proficient in reading and writing;
• Signed informed consent by the patient or their family.

You may not qualify if:

• Patients who fulfill any of the following conditions will be excluded a clear history of inducement, such as diseases caused by trauma, surgery, cognitive impairment, severe dysfunction of heart, liver, kidney and other organs, and malignant tumors, immune diseases and other malignant diseases.

Sponsors & Collaborators

• Hangzhou Medical College: lead

Study Sites (1)

the Affiliated Zhejiang Provincial People's Hospital to Hangzhou Medical College.

Hangzhou, Zhejiang, 311000, China

RECRUITING

MeSH Terms

Conditions

Spinal Cord Injuries

Interventions

Crisis Intervention

Condition Hierarchy (Ancestors)

Spinal Cord Diseases; Central Nervous System Diseases; Nervous System Diseases; Trauma, Nervous System; Wounds and Injuries

Intervention Hierarchy (Ancestors)

Psychotherapy; Behavioral Disciplines and Activities

Study Officials

• Xinyun Dr Li, doctor

  hangzhou medical colleage

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Xinyun Dr LI, Doctor

CONTACT

8618069783240; lxyjasmine2010@163.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, CARE PROVIDER, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 11, 2024
• First Posted: March 18, 2024
• Study Start: August 1, 2025
• Primary Completion: December 1, 2025
• Study Completion (Estimated): December 1, 2026
• Last Updated: February 23, 2026

Record last verified: 2026-02

Locations

CN (1)