NCT07481279

Brief Summary

Adolescent idiopathic scoliosis (AIS) is a common spinal deformity that may affect physical function and pulmonary capacity during adolescence. Exercise-based rehabilitation programs are frequently used in the conservative management of scoliosis. The aim of this study is to investigate the effects of scoliosis-specific exercises combined with upper and lower extremity progressive resistance exercises on anthropometric, clinical, and pulmonary parameters in adolescents with idiopathic scoliosis. Participants diagnosed with adolescent idiopathic scoliosis will participate in an exercise program including scoliosis-specific exercises and progressive resistance exercises targeting upper and lower extremities. Anthropometric measurements, clinical assessments, and pulmonary function parameters will be evaluated before and after the intervention. The results of this study are expected to provide evidence regarding the effectiveness of combined exercise interventions on physical and respiratory outcomes in adolescents with idiopathic scoliosis.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
24

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jun 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2025

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 30, 2026

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 30, 2026

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

March 15, 2026

Completed
3 days until next milestone

First Posted

Study publicly available on registry

March 18, 2026

Completed
Last Updated

March 18, 2026

Status Verified

March 1, 2026

Enrollment Period

8 months

First QC Date

March 15, 2026

Last Update Submit

March 15, 2026

Conditions

Keywords

ScoliosisScoliosis ExercisesProgressive Resistance ExercisePulmonary FunctionMusculoskeletal Ultrasonography

Outcome Measures

Primary Outcomes (1)

  • Muscle Thickness Measured by Ultrasonography

    Changes in diaphragm, lumbar multifidus and pectoralis major muscle thickness measured by ultrasonography.

    Baseline and after 4 weeks of exercise intervention

Secondary Outcomes (4)

  • Sit and Reach Flexibility Test

    Baseline and after 4 weeks of intervention

  • Back Scratch Test

    Baseline and after 4 weeks of intervention

  • Hand Grip Strength

    Baseline and after 4 weeks of intervention

  • Pulmonary Function Test

    Baseline and after 4 weeks of intervention

Study Arms (2)

Scoliosis Exercise Program

EXPERIMENTAL

Participants perform scoliosis-specific exercises designed to improve spinal alignment, posture, and respiratory function.

Behavioral: Scoliosis Exercises

Progressive Resistance Exercise Program

EXPERIMENTAL

Participants perform upper and lower extremity progressive resistance exercises targeting major muscle groups.

Behavioral: Progressive Resistance Exercises

Interventions

Scoliosis-specific exercise program designed to improve spinal alignment, posture, and respiratory function in adolescents with idiopathic scoliosis. The program includes supervised therapeutic exercises performed under physiotherapist guidance.

Scoliosis Exercise Program

Progressive resistance exercise program targeting upper and lower extremity muscle groups including biceps, triceps, pectoral, back, quadriceps, and hamstring muscles.

Progressive Resistance Exercise Program

Eligibility Criteria

Age12 Years - 18 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Adolescents aged between 12 and 18 years diagnosed with adolescent idiopathic scoliosis (AIS)
  • Cobb angle between 10° and 25° confirmed by radiological evaluation
  • C-type scoliosis curve pattern

You may not qualify if:

  • Presence of congenital scoliosis
  • Presence of chromosomal abnormalities
  • Presence of skeletal dysplasia
  • Presence of connective tissue disease
  • Presence of neuromuscular disease
  • Presence of metabolic diseases affecting bone metabolism
  • Calcium metabolism disorders
  • Severe autoimmune diseases
  • Severe endocrine diseases
  • Severe cognitive impairment
  • Orthopedic conditions preventing participation in exercise
  • History of spinal surgery
  • History of excisional procedure or surgery involving paravertebral muscles

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ankara Bilkent City Hospital

Ankara, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Scoliosis

Condition Hierarchy (Ancestors)

Spinal CurvaturesSpinal DiseasesBone DiseasesMusculoskeletal Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
CROSSOVER
Model Details: Participants are randomly assigned to two exercise interventions in a crossover design. One group performs scoliosis-specific exercises while the other performs progressive resistance exercises. After the first intervention period, the groups switch to the alternate intervention and outcomes are reassessed.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Researcher

Study Record Dates

First Submitted

March 15, 2026

First Posted

March 18, 2026

Study Start

June 1, 2025

Primary Completion

January 30, 2026

Study Completion

January 30, 2026

Last Updated

March 18, 2026

Record last verified: 2026-03

Data Sharing

IPD Sharing
Will not share

Locations