NCT06293404

Brief Summary

The effect of two different positions on spinal anesthesia in hip fracture surgery

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Aug 2024

Shorter than P25 for not_applicable

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 31, 2024

Completed
1 month until next milestone

First Posted

Study publicly available on registry

March 5, 2024

Completed
5 months until next milestone

Study Start

First participant enrolled

August 1, 2024

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2024

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2024

Completed
Last Updated

July 31, 2024

Status Verified

July 1, 2024

Enrollment Period

2 months

First QC Date

January 31, 2024

Last Update Submit

July 30, 2024

Conditions

Keywords

position effecthip fracturespinal anesthesia

Outcome Measures

Primary Outcomes (6)

  • Hemodynamic change

    Heart rate

    Within 3 minutes after anesthesia

  • Hemodynamic change

    Heart rate

    Within 5 minutes after anesthesia

  • Hemodynamic change

    Heart rate

    Within 10 minutes after anesthesia

  • Hemodynamic change blockade to the dependent lower limb in flexed and extended spine position.

    Heart rate

    15 minutes

  • Hemodynamic change blockade to the dependent lower limb in flexed and extended spine position.

    Heart rate

    20 minutes after anesthesia

  • Hemodynamic change blockade to the dependent lower limb in flexed and extended spine position.

    Heart rate

    30 minutes after anesthesia

Secondary Outcomes (1)

  • To compare the efficacy, duration of motor block until return to normal function in the non-operated leg after the start of injection, of bupivacaine 7.5 mg/ml when used for spinal anaesthesia in patients undergoing unilateral lower

    10 minutes after anesthesia

Other Outcomes (1)

  • To compare the efficacy of bupivacaine 7.5 mg/ml in the duration of sensory block at dermatome T10 level

    Within 1 minutes after anesthesia

Study Arms (2)

Group F

ACTIVE COMPARATOR

the lateral decubitus position, Group F will keep the spinal cord flexed for 10 minutes,

Drug: Bupivacain

Group N

OTHER

the lateral decubitus position, Group N will keep the natural position of the spinal cord in lateral decubitus for 10 minutes,

Drug: Bupivacain

Interventions

7.5 mg Bupivacaine hydrochloride (0.5% heavy Marcaine) will be used on spinal anesthesia. (each group)

Group FGroup N

Eligibility Criteria

Age18 Years - 85 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • ASA 1-2-3
  • Hip fracture
  • Age
  • BMI: 18-40

You may not qualify if:

  • ASA score of 4 and above
  • Left ventricular ejection fraction below 40%
  • Severe aortic valve stenosis
  • Obesity (BMI \>40)
  • Presence of cardiac arrhythmia
  • Having peripheral vascular disease
  • Failure of spinal block
  • Bleeding diathesis

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Hip Fractures

Interventions

Bupivacaine

Condition Hierarchy (Ancestors)

Femoral FracturesFractures, BoneWounds and InjuriesHip InjuriesLeg Injuries

Intervention Hierarchy (Ancestors)

AnilidesAmidesOrganic ChemicalsAniline CompoundsAmines

Study Officials

  • Mehmet Sahap

    Ankara City Hospital Bilkent

    STUDY DIRECTOR

Central Study Contacts

Mehmet Sahap, MD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 31, 2024

First Posted

March 5, 2024

Study Start

August 1, 2024

Primary Completion

October 1, 2024

Study Completion

December 1, 2024

Last Updated

July 31, 2024

Record last verified: 2024-07

Data Sharing

IPD Sharing
Will not share

only results