The Effect of Aromatherapy Application With Bergamot and Grapefruit Essential Oils on PMS

NCT06289764 | Completed

• 1 other identifier: 7/02/2024/131
• Study Type: interventional
• Target: 90
• Locations: 1 country
• Sites: 1

Brief Summary

Aromatherapy is;the science of using highly concentrated essential oils or essences distilled from plants to take advantage of their therapeutic properties. Essential oils or essences are obtained from various parts of plants (root, leaf, flower, bark, fruit) and used therapeutically for physical and psychological well-being. Premenstrual syndrome (PMS) is a health problem characterized by the periodic occurrence of physical, cognitive, emotional and behavioral symptoms during the luteal phase of the menstrual cycle, ending with the onset of menstruation or with the alleviation of symptoms within a few days after the onset of menstruation. It is reported that approximately 80-95% of women complain of PMS complaints. Although the use of aromatherapy in womens health is widespread, there is no study comparing bergamot and grapefruit essential oils. The aim of this study was to determine the effect of aromatherapy with bergamot and grapefruit essential oils on premenstrual syndrome and menstrual symptoms.

Conditions

Premenstrual Syndrome-PMS

Keywords

Aromatherapy; Premenstrual syndrome; Menstrual symptom

Outcome Measures

Primary Outcomes (1)

• Premenstrual syndrome scale (PMS)

  It is a five-point Likert type scale consisting of 44 questions measuring the severity of premenstrual symptoms. A minimum of 44 and a maximum of 220 points can be obtained from the scale. An increase in the score obtained from the scale indicates that the intensity of PMS symptoms increases. In the PMS scale, PMS is considered to be "present" if it exceeds 50% (110) of the total scale score (220).

  Baseline and three months later

Secondary Outcomes (1)

• Menstrual Symptom Scale

  Baseline and three months later

Study Arms (3)

Sweet almond oil

PLACEBO COMPARATOR

Premenstrual symptom scale will be applied to the participants who volunteered to participate in the study. Aromatherapy will be applied to people with a premenstrual symptom score exceeding 110. 3 groups will be formed from people with pms symptoms. 1st group will receive Bergamot essential oil, 2nd group will receive Grapefruit essential oil, 3rd group (placebo group) will receive sweet almond oil. Selected women will be allowed to smell 3 times a day, at the same time every day, for 4 days, within 7 days before menstruation. The aromatic oil will be put 3 drops on a cotton ball and the participants will smell it. Participants will be allowed to inhale the scent for 30 minutes in the fowler position at a distance of 15 cm.

Other: Sweet almond oil

Bergamot essential oil

EXPERIMENTAL

Premenstrual symptom scale will be applied to the participants who volunteered to participate in the study. Aromatherapy will be applied to people with a premenstrual symptom score exceeding 110. 3 groups will be formed from people with pms symptoms. 1st group will receive Bergamot essential oil, 2nd group will receive Grapefruit essential oil, 3rd group (placebo group) will receive sweet almond oil. Selected women will be allowed to smell 3 times a day, at the same time every day, for 4 days, within 7 days before menstruation. The aromatic oil will be put 3 drops on a cotton ball and the participants will smell it. Participants will be allowed to inhale the scent for 30 minutes in the fowler position at a distance of 15 cm

Other: Bergamot Essential Oil

Grapefruit essential oil

EXPERIMENTAL

Premenstrual symptom scale will be applied to the participants who volunteered to participate in the study. Aromatherapy will be applied to people with a premenstrual symptom score exceeding 110. 3 groups will be formed from people with pms symptoms. 1st group will receive Bergamot essential oil, 2nd group will receive Grapefruit essential oil, 3rd group (placebo group) will receive sweet almond oil. Selected women will be allowed to smell 3 times a day, at the same time every day, for 4 days, within 7 days before menstruation. The aromatic oil will be put 3 drops on a cotton ball and the participants will smell it. Participants will be allowed to inhale the scent for 30 minutes in the fowler position at a distance of 15 cm

Other: Grapefruit Essential Oil

Interventions

Bergamot Essential Oil OTHER

Selected women will be smelled 3 times a day, at the same time every day, for 4 days, within 7 days before menstruation. Application will be repeated for 3 cycles.

Bergamot essential oil

Grapefruit Essential Oil OTHER

Selected women will be smelled 3 times a day, at the same time every day, for 4 days, within 7 days before menstruation. Application will be repeated for 3 cycles.

Grapefruit essential oil

Sweet almond oil OTHER

Selected women will be smelled 3 times a day, at the same time every day, for 4 days, within 7 days before menstruation. Application will be repeated for 3 cycles

Sweet almond oil

Eligibility Criteria

• Age: 18 Years - 35 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• To be between the ages of 18-35
• Experiencing at least 5 of the pms complaints (self-report)
• Not having respiratory diseases such as asthma and bronchitis (self-report)
• No pregnancy or suspected pregnancy (self-report)
• Not being allergic to any substance (self-report)
• Not having a systemic disease such as diabetes, hypertension (self-report)

You may not qualify if:

• Under 18, over 35 years of age Not experiencing pms complaints Finding anosmia Presence of respiratory system diseases Allergic symptoms to aromatherapy Being pregnantHaving a chronic disease

Sponsors & Collaborators

• Esra ÖZER: lead
• KTO Karatay University: collaborator

Study Sites (1)

Ankara Medipol Unıversty

Ankara, Altındağ, 06000, Turkey (Türkiye)

Location

Related Publications (1)

• Ozer E, Doner SI, Dag Tuzmen H. The effect of aromatherapy intervention with Bergamot and Grapefruit essential oils on premenstrual syndrome and menstrual symptoms: a randomized controlled trial. BMC Complement Med Ther. 2025 May 1;25(1):162. doi: 10.1186/s12906-025-04857-3.

  PMID: 40312670 DERIVED

MeSH Terms

Conditions

Premenstrual Syndrome

Interventions

almond oil

Condition Hierarchy (Ancestors)

Menstruation Disturbances; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Esra Ö ÖZER, Assist Prof.

  Ankara Medipol Unıversty

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Assist Prof

Study Record Dates

• First Submitted: February 7, 2024
• First Posted: March 4, 2024
• Study Start: February 1, 2024
• Primary Completion: April 20, 2024
• Study Completion: June 24, 2024
• Last Updated: October 15, 2024

Record last verified: 2024-10

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)