Thyroid and Cortisol Hormone Response to Sepsis
1 other identifier
observational
114
0 countries
N/A
Brief Summary
Thyroid and cortisol hormone response to sepsis
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Mar 2024
Typical duration for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
February 16, 2024
CompletedFirst Posted
Study publicly available on registry
March 1, 2024
CompletedStudy Start
First participant enrolled
March 1, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 20, 2026
CompletedStudy Completion
Last participant's last visit for all outcomes
October 25, 2026
ExpectedMarch 1, 2024
February 1, 2024
2 years
February 16, 2024
February 28, 2024
Conditions
Outcome Measures
Primary Outcomes (1)
Pattern of cortisol level and thyroid function response to sepsis in ICU
Affect of sepsis on hormones at ICU:compare the change of endocrinal hormones ( TSH (mIU/L) .T3(ng/dL) .T4 ( mcg/dL) adrenocorticotropic hormone "ACTH" (pg/mL) , cortisol (µg/dL)) at time of admission, course ICU ,3rd day after discharge
From time of admission to ICU up to 3rd day after discharge
Eligibility Criteria
include Adults (≥18 years), both genders, admitted to critical care unit with sepsis Exclusion patient with Previous diagnosis of endocrinal changes (thyroid dysfunction , hypopituitarism, Addison disease, Cushing syndrome)
You may qualify if:
- The study will include Adults (≥18 years), both genders
- septic patients admitted to critical care unit
You may not qualify if:
- thyroid disease
- hypopituitarism
- Addison disease
- Cushing syndrome)
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (1)
Silva MH, Araujo MC, Diniz EM, Ceccon ME, Carvalho WB. Thyroid abnormalities in term infants with fungal sepsis. Rev Assoc Med Bras (1992). 2016 Sep;62(6):561-567. doi: 10.1590/1806-9282.62.06.561.
PMID: 27849234BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Assistant lecturer
Study Record Dates
First Submitted
February 16, 2024
First Posted
March 1, 2024
Study Start
March 1, 2024
Primary Completion
February 20, 2026
Study Completion (Estimated)
October 25, 2026
Last Updated
March 1, 2024
Record last verified: 2024-02