Digital Storytelling to Reduce Pediatric Influenza Vaccination Disparities

NCT06274359 | Terminated

• 1 other identifier: 21-3985
• Study Type: interventional
• Target: 200
• Locations: 1 country
• Sites: 2

Brief Summary

While the COVID-19 pandemic has highlighted health disparities, Black children have unduly suffered and died from seasonal influenza for decades. Through sustained partnership with Black community stakeholders, novel community-engaged research methods, and an innovative intervention approach, this proposal will explore, develop, and test a Digital Storytelling intervention to reduce influenza vaccination disparities in Black children aged 6 months to 5 years. This project will advance our understanding of engagement methods and interventions that improve health equity and serve as a model for future work to address vaccination disparities, ensuring all individuals have the chance to fulfill their potential free of preventable diseases.

Conditions

Influenza

Keywords

influenza; digital storytelling; children; health disparities

Outcome Measures

Primary Outcomes (1)

• Child influenza vaccination status at influenza season's end (defined as March 31, 2025 for season 1 and March 31, 2026 for season 2 if a 2nd season of recruitment is necessary)

  Binary variable: Vaccinated (if a child received 1 or more doses of influenza vaccine), Unvaccinated (if a child received 0 doses)

  Baseline, up to 1 year

Secondary Outcomes (3)

• Intervention Feasibility

  through study completion, an average of 1 year

• Intervention Acceptability

  through study completion, an average of 1 year

• Intervention Appropriateness

  through study completion, an average of 1 year

Study Arms (2)

Digital storytelling group

EXPERIMENTAL

Caregivers will receive a series of digital stories by text message designed to increase influenza vaccine confidence.

Behavioral: Digital storytelling

Control group

NO INTERVENTION

Caregivers will receive standard care.

Interventions

Digital storytelling BEHAVIORAL

Caregivers will receive text messages with embedded digital stories and messaging to encourage influenza vaccination.

Digital storytelling group

Eligibility Criteria

• Age: 18 Years - 90 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Caregivers of a child who is empaneled at Denver Health (e.g. had 1 well child visit in last 18 months)
• Child will be aged 6 months to 5 years during the influenza season in which the trial will be conducted (season 1: 10/1/24-3/31/25; season 2 (if needed): 10/1/25-3/31/26)
• Child has no medical contraindications to vaccination (e.g., severe allergy to one of the vaccine ingredients, history of Guillan-Barre Syndrome)

You may not qualify if:

• \- Caregivers whose first language is not English

Sponsors & Collaborators

• Denver Health and Hospital Authority: lead

Study Sites (2)

Denver Health Eastside Clinic

Denver, Colorado, 80205, United States

Location

Denver Health Park Hill Clinic

Denver, Colorado, 80207, United States

Location

Related Publications (2)

• Weiner BJ, Lewis CC, Stanick C, Powell BJ, Dorsey CN, Clary AS, Boynton MH, Halko H. Psychometric assessment of three newly developed implementation outcome measures. Implement Sci. 2017 Aug 29;12(1):108. doi: 10.1186/s13012-017-0635-3.

  PMID: 28851459 RESULT

• Williams JTB, Kurlandsky K, Stein AB, Bharadwaj N, Hambidge SJ, Pereira RI, O'Leary SC, Johnson D, O'Leary ST. Narrative Reminder Recall to Improve Pediatric Influenza Vaccination: A Pilot Randomized Clinical Trial. JAMA Netw Open. 2026 Jan 2;9(1):e2552149. doi: 10.1001/jamanetworkopen.2025.52149.

  PMID: 41493783 DERIVED

MeSH Terms

Conditions

Influenza, Human

Condition Hierarchy (Ancestors)

Respiratory Tract Infections; Infections; Orthomyxoviridae Infections; RNA Virus Infections; Virus Diseases; Respiratory Tract Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Caregivers will be assigned randomly to receive a series of digital stories by text message or to receive usual care.

Study Record Dates

• First Submitted: January 18, 2024
• First Posted: February 23, 2024
• Study Start: August 2, 2024
• Primary Completion: March 10, 2025
• Study Completion: March 10, 2025
• Last Updated: May 14, 2025

Record last verified: 2024-01

Data Sharing

• IPD Sharing: Will not share

Locations

US (2)