Comparison of the Effect of Warfarin and Direct Oral Anticoagulants

NCT06269302 | Completed

• 1 other identifier: 2
• Study Type: observational
• Target: 346
• Locations: 1 country
• Sites: 1

Brief Summary

In this study, it was aimed to compare the frequency of new oral anticoagulants and warfarin usage, and to reveal the rates of recurrent upper gastrointestinal bleeding among patients who applied to our hospital with upper gastrointestinal bleeding

Conditions

Anticoagulants and Bleeding Disorders; Gastrointestinal Hemorrhage

Keywords

Gastrointestinal System; Oral Anticoagulant; Rebleeding; upper gastrointestinal system bleeding

Outcome Measures

Primary Outcomes (1)

• Change in the incidence of recurrent bleeding

  Increase or decrease in the incidence of recurrent bleeding

  12 months

Study Arms (1)

Patients with recurrent gastrointestinal bleeding

The data of all patients who applied to Samsun Training and Research Hospital for 12 months in 2022 and diagnosis of upper gastrointestinal bleeding and hospitalized by Internal Medicine and Gastroenterology clinics or who underwent outpatient endoscopy were included in the study.Patients who had recurrent upper GI bleeding were detected by controlling them over the hospital software system and by reaching each patient again. The frequency of use of new generation oral anticoagulants in patients with rebleeding was determined, and data such as rebleeding rate, length of hospital stay, need for transfusion, and mortality were analyzed in the groups who did not use this drug and those who used it.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All patients who were admitted to Samsun Training and Research Hospital with a diagnosis of upper gastrointestinal bleeding and hospitalized by Internal Medicine and Gastroenterology clinics or who underwent outpatient endoscopy were included in the study.

You may qualify if:

• Age \>18 years old
• Upper gastrointestinal bleeding
• months follow-up

You may not qualify if:

• Age \<18 years old
• Lower gastrointestinal bleeding
• Esophageal variceal bleeding

Sponsors & Collaborators

• Samsun Education and Research Hospital: lead

Study Sites (1)

Samsun Education and Research Hospital

Samsun, İlkadım, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Hemostatic Disorders; Gastrointestinal Hemorrhage

Condition Hierarchy (Ancestors)

Vascular Diseases; Cardiovascular Diseases; Hemorrhagic Disorders; Hematologic Diseases; Hemic and Lymphatic Diseases; Gastrointestinal Diseases; Digestive System Diseases; Hemorrhage; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• DÜRİYE SILA KARAGÖZ ÖZEN, MD

  Samsun Education and Research Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: MD, Internal Medicine Specialist

Study Record Dates

• First Submitted: February 12, 2024
• First Posted: February 21, 2024
• Study Start: January 1, 2022
• Primary Completion: December 31, 2022
• Study Completion: December 31, 2022
• Last Updated: February 21, 2024

Record last verified: 2024-02

Locations

TU (1)