The Impact of Hypoxia on the Biochemical and Morphological Parameters of Blood in Rowers.

NCT06264193 | Completed

• 1 other identifier: Rowers LH-TL
• Study Type: interventional
• Target: 13
• Locations: 0 countries
• Sites: N/A

Brief Summary

The response to hypoxia is very individual and epending on many aspects, such as the type of training, duration, intensity, or hypoxic stimulus, hypoxia affects the athlete in various ways. The results of this study have shown that 18 days of the LH-TL method does not significantly increase the level of EPO and VEGF in rowers. However, reticulocytes, immature red blood cells, have shown significant differences after 18-d LH-TL between groups. Further research should be carried out to investigate an optimal hypoxic dose and time, which will raise EPO, VEGF, and morphology variables.

Conditions

Hypoxia

Keywords

hypoxia; rowers; exercise; EPO; athletes; LH-TL

Outcome Measures

Primary Outcomes (2)

• Erythropoietin (EPO) mlU/ml

  immunoenzymatic assay methods using diagnostic kits

  At the beginning of the camp (Baseline), after 5 days (T1), after 12 days (T2), and after 18 days (T3) of the camp.

• vascular endothelial growth factor (VEGF) mlU/ml

  immunoenzymatic assay methods using diagnostic kits

  At the beginning of the camp (Baseline), after 5 days (T1), after 12 days (T2), and after 18 days (T3) of the camp.

Secondary Outcomes (9)

• creatine kinase (CK) ng/ml

  At the beginning of the camp (Baseline), after 5 days (T1), after 12 days (T2), and after 18 days (T3) of the camp.

• Hs C-Reactive Protein (hsCRP) mg/L

  At the beginning of the camp (Baseline), after 5 days (T1), after 12 days (T2), and after 18 days (T3) of the camp.

• hemoglobin (Hb)g/dL

  At the beginning of the camp (Baseline), after 5 days (T1), after 12 days (T2), and after 18 days (T3) of the camp.

• hematocrit (Htc)%

  At the beginning of the camp (Baseline), after 5 days (T1), after 12 days (T2), and after 18 days (T3) of the camp.

• red blood cells (RBC)mln/mm3

  At the beginning of the camp (Baseline), after 5 days (T1), after 12 days (T2), and after 18 days (T3) of the camp.

Study Arms (1)

Hypoxia

EXPERIMENTAL

live high-train low method was used

Other: hypoxia

Interventions

hypoxia OTHER

The athletes were living in hypoxic rooms, and training was carried out on lowlands.

Hypoxia

Eligibility Criteria

• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• member of national rower's teams, and sports camp participant.

You may not qualify if:

• negative symptoms of hypoxia, and/or injury.

Sponsors & Collaborators

• Poznan University of Physical Education: lead

Related Publications (4)

• Kasperska A, Zembron-Lacny A. The effect of intermittent hypoxic exposure on erythropoietic response and hematological variables in elite athletes. Physiol Res. 2020 Apr 30;69(2):283-290. doi: 10.33549/physiolres.934316. Epub 2020 Mar 23.

  PMID: 32199016 BACKGROUND

• Wilber RL. Application of altitude/hypoxic training by elite athletes. Med Sci Sports Exerc. 2007 Sep;39(9):1610-24. doi: 10.1249/mss.0b013e3180de49e6.

  PMID: 17805095 BACKGROUND

• Czuba M, Fidos-Czuba O, Ploszczyca K, Zajac A, Langfort J. Comparison of the effect of intermittent hypoxic training vs. the live high, train low strategy on aerobic capacity and sports performance in cyclists in normoxia. Biol Sport. 2018 Mar;35(1):39-48. doi: 10.5114/biolsport.2018.70750. Epub 2017 Oct 11.

  PMID: 30237660 RESULT

• Ploszczyca K, Langfort J, Czuba M. The Effects of Altitude Training on Erythropoietic Response and Hematological Variables in Adult Athletes: A Narrative Review. Front Physiol. 2018 Apr 11;9:375. doi: 10.3389/fphys.2018.00375. eCollection 2018.

  PMID: 29695978 RESULT

Related Links

• Exercise and Training at Altitudes: Physiological Effects and Protocols

MeSH Terms

Conditions

Hypoxia; Motor Activity

Condition Hierarchy (Ancestors)

Signs and Symptoms, Respiratory; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Behavior

Study Officials

• Anna Kasperska

  Poznań University of Physical Education, Faculty of Sport Sciences in Gorzów Wielkopolski, Poland;

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: The hypoxic group included rowers participating in sports training and the LH-TL method, hypoxic rooms (FiO2=14.5%, corresponds to an altitude of 3000 meters). And the control group participating only in sports training and living in normoxic rooms, at the same sports camp.

Study Record Dates

• First Submitted: January 10, 2024
• First Posted: February 16, 2024
• Study Start: November 30, 2014
• Primary Completion: December 21, 2014
• Study Completion: December 21, 2014
• Last Updated: January 17, 2025

Record last verified: 2023-11

Data Sharing

• IPD Sharing: Will not share