NCT06260215

Brief Summary

This study aims at investigating the recovery kinetics of skeletal muscle damage, neuromuscular fatigue and performance following a single soccer trainning session in middle aged males. The participants will perform a soccer training session \[A single training session including 60 minutes of warm up, soccer technical exercises and small-sided game\] and a cotrol trial (No intervention included, only daily measurements) in randomized, repeated measures, crossover design. Assesesments related to skeletal muscle damage, performance and neuromuscular fatigue will be executed before the training session and daily for four consecutive days after training.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
11

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Feb 2024

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 29, 2024

Completed
7 days until next milestone

Study Start

First participant enrolled

February 5, 2024

Completed
10 days until next milestone

First Posted

Study publicly available on registry

February 15, 2024

Completed
11 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 26, 2024

Completed
12 days until next milestone

Study Completion

Last participant's last visit for all outcomes

March 9, 2024

Completed
Last Updated

December 2, 2025

Status Verified

February 1, 2024

Enrollment Period

21 days

First QC Date

January 29, 2024

Last Update Submit

November 24, 2025

Conditions

Keywords

RecoverySoccerSoccer trainingperformanceinflammation

Outcome Measures

Primary Outcomes (17)

  • Change in White blood cell count

    White blood cell count will be measured using an automatic blood analyzer

    At baseline, at 24, 48 and 72 hours after soccer training

  • Change in Granulocyte cell count

    Change in White blood cell count will be measured using an automatic blood analyzer

    At baseline, at 24, 48 and 72 hours after soccer training

  • Change in Platelets cell count

    Platelets cell count will be measured using an automatic blood analyzer

    At baseline, at 24, 48 and 72 hours after soccer training

  • Change in Monocyte cell count

    Monocytes cell count will be measured using an automatic blood analyzer

    At baseline, at 24, 48 and 72 hours after soccer training

  • Change in Lymphocyte cell count

    Lymphocyte cell count will be measured using an automatic blood analyzer

    At baseline, at 24, 48 and 72 hours after soccer training

  • Change in percentage of Hematocrit level

    The percentage of Hematocrit level will be measured using an automatic blood analyzer

    At baseline, at 24, 48 and 72 hours after soccer training

  • Change Red blood cells count

    Red blood cells count will be measured using an automatic blood analyzer

    At baseline, at 24, 48 and 72 hours after soccer training

  • Change in Hemoglobin level

    Hemoglobin level will be measured using an automatic blood analyzer

    At baseline, at 24, 48 and 72 hours after soccer training

  • Change in Creatine kinase activity

    Creatine kinase activity will be measured in plasma

    At baseline, at 24, 48 and 72 hours after soccer training

  • Change in Total antioxidant capacity

    Total antioxidant capacity will be measured in plasma

    At baseline, at 24, 48 and 72 hours after soccer training

  • Change in Glutathione concentration in blood

    Glutathione concentration will be measured in red blood cells

    At baseline, at 24, 48 and 72 hours after soccer training

  • Change in countermovement jump height

    countermovement jump height will be measured using a force platform

    At baseline, at 24, 48, 72 and 96 hours after soccer training

  • Change in Peak power during coutermovement jump test

    The peak power will be measured using a force platform

    At baseline, at 24, 48, 72 and 96 hours after soccer training

  • Change in isometric peak torque of knee extensors and flexors

    Isometric peak torque will be assessed on an isokinetic dynamometer

    At baseline, at 24, 48, 72 and 96 hours after soccer training

  • Change in sprint time of 10 m

    10m sprint time will be assessed using light cells

    At baseline, at 24, 48, 72 and 96 hours after soccer training

  • Change in sprint time of 30 m

    30m sprint time will be assessed using light cells

    At baseline, at 24, 48, 72 and 96 hours after soccer training

  • Change in delayed onset of muscle soreness

    Muscle soreness will be assessed by palpation of muscle belly and the distal region

    At baseline, at 24, 48, 72 and 96 hours after soccer training

Secondary Outcomes (13)

  • Dietary intake

    At baseline

  • Peak Maximal oxygen consumption (Peak VO2)

    At baseline

  • Body Mass

    At baseline

  • Body Height

    At baseline

  • Body Fat

    At baseline

  • +8 more secondary outcomes

Study Arms (2)

Control

NO INTERVENTION

Participants in this arm will receive no intervention

SoccerTraining

EXPERIMENTAL

Participants in this arm will participate in a soccer training (ST) session for 60 minutes. During the training the participans will execute the warm-up process, the part of soccer technical exercises and they will play a small-side-game.

Other: ST

Interventions

STOTHER

Participants will perform a soccer training (ST) session for 60 minutes. The training will include the warm-up, soccer technical exercises and a small-side game

SoccerTraining

Eligibility Criteria

Age40 Years - 60 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Free of musculoskeletal injuries
  • No use of ergogenic supplements or medication
  • Free of chronic diseases
  • age of 40-60 years

You may not qualify if:

  • Musculoskeletal injury
  • Use of alcohol, caffeine and any type of ergogenic supplements or medication during the course of the study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University o Thessaly, School of Physical Education and Sports Science

Trikala, 42100, Greece

Location

MeSH Terms

Conditions

Inflammation

Condition Hierarchy (Ancestors)

Pathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Ioannis G Fatouros, Prof

    University of Thessaly

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

January 29, 2024

First Posted

February 15, 2024

Study Start

February 5, 2024

Primary Completion

February 26, 2024

Study Completion

March 9, 2024

Last Updated

December 2, 2025

Record last verified: 2024-02

Locations