Role of PCO2 Gap as Predictor of Clinical Outcome in ICU Septic Patients
PCO2
Comparison Between PCO2 Gap, Lactate and Procalcitonin as Predictors of Clinical Outcome in ICU Septic Patients
1 other identifier
observational
80
0 countries
N/A
Brief Summary
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection, if not recognized early and managed promptly, it can lead to septic shock, multiple organ failure and death. Sepsis is associated with high mortality, and the early recognition of the signs of tissue hypo perfusion is crucial in its management. This prospective study was aimed to detect that PCO2 gap can be taken as a reliable prognostic tool in septic patients
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Feb 2024
Shorter than P25 for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
January 31, 2024
CompletedStudy Start
First participant enrolled
February 1, 2024
CompletedFirst Posted
Study publicly available on registry
February 13, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 1, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2024
CompletedFebruary 13, 2024
February 1, 2024
3 months
January 31, 2024
February 10, 2024
Conditions
Outcome Measures
Primary Outcomes (1)
prediction of clinical outcome in ICU septic patients
PCO2 gap mmHg will be measured on admission and after 48 hours
48 hours
Study Arms (2)
Group S
survivors
Group M
non survivors
Interventions
measurement of serum lactate, procalcitonin and PCO2 gap
Eligibility Criteria
patients admitted in ICU departments with sepsis
You may qualify if:
- Adult septic patients ≥ 21 years old
You may not qualify if:
- Patients with history of chronic obstructive pulmonary disease and bronchial asthma.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- lecturer of anesthesia
Study Record Dates
First Submitted
January 31, 2024
First Posted
February 13, 2024
Study Start
February 1, 2024
Primary Completion
May 1, 2024
Study Completion
June 1, 2024
Last Updated
February 13, 2024
Record last verified: 2024-02