NCT06244901

Brief Summary

This feasibility study looks to evaluate ankle exoskeleton assistance in community settings for individuals with cerebral palsy.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
10

participants targeted

Target at below P25 for early_phase_1

Timeline
Completed

Started Oct 2023

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 13, 2023

Completed
3 months until next milestone

Study Start

First participant enrolled

October 25, 2023

Completed
3 months until next milestone

First Posted

Study publicly available on registry

February 6, 2024

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2025

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2025

Completed
Last Updated

February 6, 2024

Status Verified

January 1, 2024

Enrollment Period

1.5 years

First QC Date

July 13, 2023

Last Update Submit

January 29, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • Walking speed

    Change in walking speed (measured in meters per second)

    through study completion, an average of one week

Secondary Outcomes (3)

  • Step length

    Through study completion, an average of one week

  • Heart-rate

    Through study completion, an average of one week

  • Perceived exertion

    Through study completion, an average of one week

Study Arms (2)

Exoskeleton Walking

EXPERIMENTAL

Walking with ankle exoskeleton assistance

Device: Ankle Exoskeleton

Normal walking

PLACEBO COMPARATOR

Walking under normal conditions (no exoskeleton)

Other: Normal walking

Interventions

Walking for twenty minutes with a wearable powered robotic ankle exoskeleton on real-world terrain every day for a week.

Exoskeleton Walking

Normal walking for twenty minutes on real-world terrain every day for a week.

Normal walking

Eligibility Criteria

Age12 Years - 45 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Diagnosis of cerebral palsy
  • Gross Motor Function Classification Level I, II, or III
  • Able to walk for at least 20 minutes with or without a walking aid
  • Able to safely fit into a device configuration and tolerate assistance without knee hyperextension while walking
  • Able to provide verbal assent, if appropriate. If the participant is non-verbal, parental interpretation of gesticulation for assent will be used.

You may not qualify if:

  • Any neurological, musculoskeletal or cardiorespiratory injury, health condition ( including pregnancy), or diagnosis other than cerebral palsy that would affect the ability to walk as directed for short periods of time.
  • Participant or parent report that the perspective participant's physician has recommended that they not engage in moderate intensity walking exercise.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Northern Arizona University

Flagstaff, Arizona, 86011, United States

RECRUITING

MeSH Terms

Conditions

Cerebral Palsy

Condition Hierarchy (Ancestors)

Brain Damage, ChronicBrain DiseasesCentral Nervous System DiseasesNervous System Diseases

Central Study Contacts

Zach Lerner, PhD

CONTACT

Study Design

Study Type
interventional
Phase
early phase 1
Allocation
RANDOMIZED
Masking
NONE
Purpose
DEVICE FEASIBILITY
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 13, 2023

First Posted

February 6, 2024

Study Start

October 25, 2023

Primary Completion

May 1, 2025

Study Completion

September 1, 2025

Last Updated

February 6, 2024

Record last verified: 2024-01

Data Sharing

IPD Sharing
Will not share

Locations