Ultrasound to Evaluate Acute Kidney Injury

NCT06241417 | Not Yet Recruiting

• 1 other identifier: 2023ZDSYLL379-P01
• Study Type: observational
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

Acute kidney injury is a common complication in critically ill patients. This condition can significantly prolong the length of hospital stay, increase the cost of hospitalization, and have a high mortality rate and a poor prognosis. Early assessment of patients' prognosis with acute kidney injury is vital for clinical treatment. Point-of-care ultrasound and renal injury biomarkers can be used to evaluate kidney injury at different levels. Therefore, it is speculated that dynamic monitoring can accurately predict the prognosis of patients with kidney injury.

Conditions

Acute Kidney Injury; Critically Ill

Outcome Measures

Primary Outcomes (1)

• Rate of acute kidney disease

  AKD was defined by presenting at least KDIGO Stage 1 criteria for \>7 days after enrollment

  Seven days after enrollment

Study Arms (2)

renal recovery

Renal recovery was defined as not satisfied by AKI criteria which was defined by KDIGO.

non renal recovery

Non renal recovery was defined by presenting at least KDIGO Stage 1 criteria or death.

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Acute kidney injury patients in intensive care unit.

You may qualify if:

• Meets diagnostic criteria for AKI (according to KDIGO guidelines); Age ≥ 18 years and ≤ 80 years

You may not qualify if:

• Chronic kidney disease stage IV-V, maintenance hemodialysis; Kidney tumors; History of kidney transplantation; Nephrectomy; Pregnancy; Arrhythmias that affect the measurement of renal ultrasound.

Sponsors & Collaborators

• Southeast University, China: lead

Study Sites (1)

Zhongda Hospital Affiliated to Southeast University

Nanjing, Jiangsu, 210000, China

Location

Biospecimen

Retention: SAMPLES WITHOUT DNA

urine and plasma

MeSH Terms

Conditions

Acute Kidney Injury; Critical Illness

Condition Hierarchy (Ancestors)

Renal Insufficiency; Kidney Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associated Professor of Critical Care Medcine

Study Record Dates

• First Submitted: January 23, 2024
• First Posted: February 5, 2024
• Study Start: January 25, 2024
• Primary Completion: May 31, 2024
• Study Completion: June 30, 2024
• Last Updated: February 5, 2024

Record last verified: 2024-02

Locations

CN (1)