Bodyweight Interval Exercise in the Fed Versus Fasted State

NCT06240442 | Completed

• 1 other identifier: 40799
• Study Type: interventional
• Target: 12
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to investigate the effects of a single session of at-home bodyweight interval exercise, performed in the fasted or fed state, on postprandial glycemic management, post-exercise fat oxidation, and overall perceptions of appetite in recreationally active females. This is a remote/online study and does not involve any visits to the laboratory.

Conditions

Exercise

Outcome Measures

Primary Outcomes (1)

• Average blood glucose concentration

  Average blood glucose concentration during postprandial period

  2 hours

Secondary Outcomes (5)

• Blood glucose concentration

  2 hours

• Blood glucose area under the curve

  2 hours

• Peak blood glucose concentration

  2 hours

• Post-exercise fat oxidation

  pre-exercise, immediately post-exercise, up to 3 hours post-exercise

• Appetite Perceptions

  pre-exercise, immediately post-exercise, and 1, 2 and 3 hours post-exercise

Study Arms (2)

Fasted Exercise

EXPERIMENTAL

Exercise followed by breakfast

Other: Fasted exercise

Fed Exercise

EXPERIMENTAL

Breakfast followed by exercise

Other: Fed exercise

Interventions

Fasted exercise OTHER

Bodyweight interval exercise performed 5 minutes before the start of a mixed-macronutrient breakfast meal

Fasted Exercise

Fed exercise OTHER

Bodyweight interval exercise performed 10 minutes after the start of consuming a mixed-macronutrient breakfast meal

Fed Exercise

Eligibility Criteria

• Age: 18 Years - 35 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Females 18-35 years
• Recreationally active (complete \<150 min of exercise 1-3 days per week) and not training for any specific sport
• Experiencing monthly menstrual periods (eumenorrheic)
• Are not currently on oral contraceptives, or are taking triphasic oral contraceptives
• Body mass index (BMI) ≥18.5 kg/m2 and ≤30 kg/m2
• Regular consumption of a breakfast meal (solid and liquid meals apply) most (≥ 4) days of the week
• Have a device compatible for use with study applications (e.g., smart phone)

You may not qualify if:

• Inability to safely perform physical activity as determined by the Get Active Questionnaire
• Not willing to consume the standardized test drink before and after exercise
• Sensitive to meal timing around exercise (e.g., gastrointestinal issues if exercise performed 10 min after the start of meal consumption or if a meal is consumed 5 min after exercise)
• Inability to adhere to pre-trial protocol guidelines (e.g., caffeine or alcohol restrictions)
• Physical limitations for bodyweight exercise
• Are on monophasic or biphasic oral contraceptives
• Regular tobacco or cannabis use (e.g., recreational and/or medical cannabis, cigarettes, e-cigarettes, vape pens, JUUL)
• Regular use of drugs that may alter metabolism (e.g., corticosteroids, nSAIDs)
• Diagnosed medical condition under the care of care of a physician (e.g., type 2 diabetes, cardiovascular disease) Currently enrolled in a course with Dr. Gillen

Sponsors & Collaborators

• University of Toronto: lead

Study Sites (1)

Goldring Centre for High Performance Sport

Toronto, Ontario, M5S 2C9, Canada

Location

MeSH Terms

Conditions

Motor Activity

Condition Hierarchy (Ancestors)

Behavior

Study Officials

• Jenna Gillen, PhD

  University of Toronto

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: January 14, 2024
• First Posted: February 5, 2024
• Study Start: May 14, 2021
• Primary Completion: August 30, 2021
• Study Completion: August 30, 2021
• Last Updated: February 5, 2024

Record last verified: 2024-01

Data Sharing

• IPD Sharing: Will not share

Locations

CA (1)