Cognitive and Neural Assessment Platform and Localized Norm for Macau Older Adults.
Establishing Cognitive and Neural Assessment Platform and Localized Norm for Macau Older Adults
2 other identifiers
observational
300
1 country
1
Brief Summary
The current project is dedicated to creating a comprehensive cognitive and neural assessment platform and corresponding norms tailored specifically to the older adults in Macau.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Feb 2024
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
January 15, 2024
CompletedStudy Start
First participant enrolled
February 1, 2024
CompletedFirst Posted
Study publicly available on registry
February 2, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 30, 2026
CompletedStudy Completion
Last participant's last visit for all outcomes
December 30, 2026
ExpectedFebruary 2, 2024
January 1, 2024
2.2 years
January 15, 2024
January 25, 2024
Conditions
Keywords
Outcome Measures
Primary Outcomes (3)
Normative Data for the Montreal Cognitive Assessment - Chinese (Hong Kong) version
The MoCA will be administered to derive a normative data set representative of the older adult population in Macau.
From February 2024 to January 2026
Normative Data for the Mini-Mental State Examination (MMSE)
The MMSE will be administered to derive a normative data set representative of the older adult population in Macau.
From February 2024 to January 2026
Normative Scores for Computerized Neuropsychological Tasks
Neuropsychological tasks will be employed to measure selective attention capacity and processing speed in the study cohort. These tasks will provide quantifiable data on the efficiency and accuracy of cognitive processing. The collective performance on these tasks will be used to establish benchmark values - including means, medians, and ranges - that define the normative standards for these cognitive abilities in the population.
From February 2024 to January 2026
Secondary Outcomes (3)
Neural Activation Patterns During Cognitive Tasks as Revealed by Functional Magnetic Resonance Imaging (fMRI)
From February 2024 to January 2026
Cerebral Hemodynamics Assessed Through Functional Near-Infrared Spectroscopy (fNIRS)
From February 2024 to January 2026
Electrophysiological Correlates of Cognitive Activity as Measured by Electroencephalography (EEG)
From February 2024 to January 2026
Study Arms (2)
Group 1
Older adults
Group 2
Younger adults
Eligibility Criteria
Adults above 50 years old from the Macau local community.
You may qualify if:
- Must be a local adult resident of Macau
- Age above 50 years for older adult cohort
- Younger adults individuals above 18 will be included as control comparators
You may not qualify if:
- History of neurological injury or disease
- Current use of medications that affect brain function or blood flow
- Contraindications to MRI scanning, such as the presence of an electric/mechanical implant or device (e.g., pacemaker)
- Claustrophobia
- Body weight over 300 lbs due to weight and physical constraints of the scanner (i.e., bore size limited to 55 cm)
- Inability to provide informed consent
- Pregnancy
- Being under the legal age of adulthood (children)
- Incarcerated individuals (prisoners)
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Centre for Cognitive and Brain Sciences of the University of Macau
Macao, Macao SAR, 999078, Macau
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Haoyun ZHANG Assistant Professor, Ph.D
University of Macau
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- ECOLOGIC OR COMMUNITY
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
January 15, 2024
First Posted
February 2, 2024
Study Start
February 1, 2024
Primary Completion
March 30, 2026
Study Completion (Estimated)
December 30, 2026
Last Updated
February 2, 2024
Record last verified: 2024-01