NCT06235008

Brief Summary

This is an observational retrospective multi-center study in patients managed for acute dyspnea by Emergency department medical team. The main aim of the study is to evaluate factors associated with mortality risks in patients managed for acute dyspnea by an Emergency department medical team, overall, as well as in subgroups of interest (male/female, age categories, mode of admission and comorbidities).

Trial Health

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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
75,000

participants targeted

Target at P75+ for all trials

Timeline
53mo left

Started Mar 2024

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress32%
Mar 2024Sep 2030

First Submitted

Initial submission to the registry

January 9, 2024

Completed
22 days until next milestone

First Posted

Study publicly available on registry

January 31, 2024

Completed
2 months until next milestone

Study Start

First participant enrolled

March 31, 2024

Completed
5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 31, 2029

Expected
1.5 years until next milestone

Study Completion

Last participant's last visit for all outcomes

September 30, 2030

Last Updated

January 31, 2024

Status Verified

January 1, 2024

Enrollment Period

5 years

First QC Date

January 9, 2024

Last Update Submit

January 22, 2024

Conditions

Dyspnea

Outcome Measures

Primary Outcomes (1)

  • All-cause mortality

    Within 5 years following hospital discharge

Secondary Outcomes (11)

  • Main diagnosis during the initial hospitalization

    Within hospital stay, maximum 21 days

  • Mismatch between diagnosis in the Emergency department and at discharge

    Within hospital stay, maximum 21 days

  • Length of hospital stay

    Within hospital stay, maximum 21 days

  • Administration of non-invasive ventilation

    Within hospital stay, maximum 21 days

  • Timing of non-invasive ventilation

    Within hospital stay, maximum 21 days

  • +6 more secondary outcomes

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients with acute dyspnea cared by a medical team of the emergencies of CHRU of Nancy, CHR Metz-Thionville and CH d'Epinal

You may qualify if:

  • Man or women ≥ 18 years
  • Patients with acute dyspnea cared by a medical team of the emergencies of CHRU of Nancy, CHR Metz-Thionville and CH d'Epinal.

You may not qualify if:

  • Cardiorespiratory arrest before medical management by the Emergency Department team
  • Adults under legal protection

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CHRU

Nancy, France

Location

MeSH Terms

Conditions

Dyspnea

Condition Hierarchy (Ancestors)

Respiration DisordersRespiratory Tract DiseasesSigns and Symptoms, RespiratorySigns and SymptomsPathological Conditions, Signs and Symptoms

Central Study Contacts

GIRERD Nicolas

CONTACT

0383157322n.girerd@chru-nancy.fr

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Clinical Professor

Study Record Dates

First Submitted

January 9, 2024

First Posted

January 31, 2024

Study Start

March 31, 2024

Primary Completion (Estimated)

March 31, 2029

Study Completion (Estimated)

September 30, 2030

Last Updated

January 31, 2024

Record last verified: 2024-01

Locations

FR(1)