Baduanjin Versus Brisk Walking for Cognition in Schizophrenia

NCT06226779 | Completed

• 1 other identifier: 202400006B0
• Study Type: interventional
• Target: 63
• Locations: 1 country
• Sites: 1

Brief Summary

The current study intends to recruit participants with schizophrenia for the practice of Baduanjin, brisk walking, and health education after enrollment. The study also including a maintenance program. Cognitive and physical function assessments will be conducted before, after, and during follow-up tests. The research hypothesis posits that both Baduanjin and brisk walking will confer beneficial effects on various aspects of cognitive and physical functions.

Conditions

Schizophrenia; Exercise; Condition

Keywords

schizophrenia, mindful exercise, exercise, cognition

Outcome Measures

Primary Outcomes (6)

• Change score of the Brief Assessment of Cognition in Schizophrenia (BACS)

  BACS is a battery of cognition tests that measure verbal memory, working memory, motor speed, verbal fluency, attention and processing speed, and executive function.The BACS is comprised of seven subtests: (1) the List Learning Test, (2) Digit Sequencing Test, (3) Token Motor Test, (4) Category Instance Test, (5) Controlled Oral Word Association Test, (6) Symbol Coding, and (7) Tower of London Test.

  Baseline, immediate after treatment, 4-week follow up

• Change scores of 6-minute walk test

  This test evaluates cardiovascular fitness and walking speed.

  Baseline, immediate after treatment, 4-week follow up

• Change scores of 30-second chair stand test

  This test evaluates muscular endurance of lower-extremities.

  Baseline, immediate after treatment, 4-week follow up

• Change scores of Timed up-and-go test

  This test evaluates functional mobility, agility and balance

  Baseline, immediate after treatment, 4-week follow up

• Change scores of dual task Timed up-and-go test (manual)

  This test requires carry a cup of water 3 cm from the top of the cup while performing the Timed up-and-go test. It evaluates dual task performance.

  Baseline, immediate after treatment, 4-week follow up

• Change scores of dual task Timed up-and-go test (cognitive)

  This test combine serial three counting and Timed up-and-go test simultaneously. It evaluates dual task performance.

  Baseline, immediate after treatment, 4-week follow up

Secondary Outcomes (2)

• Change score of Depression, Anxiety Stress Scales-21 (DASS-21)

  Baseline, immediate after treatment, 4-week follow up

• Change score of Pittsburg Sleep Quality Index

  Baseline, immediate after treatment, 4-week follow up

Study Arms (3)

Baduanjin

EXPERIMENTAL

Parcipants will practice baduanjin exercise.

Behavioral: Baduanjin exercsie

Brisk walking

ACTIVE COMPARATOR

Parcipants will perform brisk walking activities.

Behavioral: Brisk walking

health education

OTHER

Parcipants will receive health education classes and watch sport related videos.

Behavioral: Health education

Interventions

Baduanjin exercsie BEHAVIORAL

The Baduanjin exercise consists of 8 postures, with emphasis on different body parts. The exercise is commonly practiced as follows: (1) 2 hands holding up the heavens, (2) drawing the bow to shoot the eagle, (3) separating the heaven and earth, (4) wise owl gazing backwards, (5) swaying the head and shaking the tail, (6) 2 hands holding the feet to strengthen the waist, (7) clenching the fists and glaring fiercely, and (8) bouncing on the toes.

Also known as: Mindful baduanjin

Baduanjin

Brisk walking BEHAVIORAL

The brisk walking will be gradually increased physical exertion from light to moderate of intensity. During the training period, the heart rate of participants will be monitored.

Also known as: aerobic walking

Brisk walking

Health education BEHAVIORAL

Health education will include lecture classes. Video watching will watch videos which were not aim at improving physical exertion, such as sports games or sports related variety shows

Also known as: video watching

health education

Eligibility Criteria

• Age: 20 Years - 65 Years
• Gender Eligibility Details: Based on self-representation of gender identity.
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Having a diagnosis of schizophrenia according to the DSM-5.
• Who will be above 20-65 years of age .
• Having a stable mental status without shift in medication and keep in same dose for at least one month.
• Being able to walk independently for 50 meters.

You may not qualify if:

• Serious physical conditions that will impede participation, such as cardiovascular disease, musculoskeletal disease or pulmonary system disease.
• Visual or auditory impairment that precludes completion of assessment.
• Acute psychosis requiring hospitalization.
• Presence of severe withdrawal or profound cognitive disability that cause difficulties in following instructions.

Sponsors & Collaborators

• Chang Gung Memorial Hospital: lead

Study Sites (1)

Chang Gung Memorial Hospital, Kaohsiung Medical Center

Kaohsiung City, 833, Taiwan

Location

MeSH Terms

Conditions

Schizophrenia; Motor Activity; Disease

Condition Hierarchy (Ancestors)

Schizophrenia Spectrum and Other Psychotic Disorders; Mental Disorders; Behavior; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Chen Chyi-Rong, Master

  Chang gung memorial hospital, Kaohsiung branch

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Occupational therapist

Study Record Dates

• First Submitted: January 18, 2024
• First Posted: January 26, 2024
• Study Start: January 16, 2024
• Primary Completion: January 15, 2025
• Study Completion: January 15, 2025
• Last Updated: July 29, 2025

Record last verified: 2025-05

Data Sharing

• IPD Sharing: Will not share

Locations

TW (1)