Baduanjin on Patients With Schizophrenia

NCT04430309 | Completed

• 1 other identifier: 202000817B0
• Study Type: interventional
• Target: 48
• Locations: 1 country
• Sites: 1

Brief Summary

As an ancient, popular Chinese exercise, Baduanjin is characterized by symmetrical posture, deep breathing and meditation and easy to learn. Previous studies showed immediate effect of Baduanjin on cognition in patients with schizophrenia.The purpose of this study is to investigate the immediate effect and chronic effect of Baduanjin exercise on physical fitness, cognition and daily functions in middle-aged and older adults with schizophrenia.

Conditions

Schizophrenia

Keywords

Schizophrenia, mind body intervention ,Baduanjin

Outcome Measures

Primary Outcomes (6)

• Change scores of 6-minute walk test

  This test evaluates cardiovascular fitness and walking speed.

  Baseline, immediate after treatment, 4-week follow up

• Change scores of 30-second chair stand test

  This test evaluates muscular endurance of lower-extremities.

  Baseline, immediate after treatment, 4-week follow up

• Change scores of Timed up-and-go test

  This test evaluates functional mobility, agility and balance

  Baseline, immediate after treatment, 4-week follow up

• Change scores of Montreal cognitive assessment

  This test evaluates global cognition.

  Baseline, immediate after treatment, 4-week follow up

• Change scores of Trail making test (part A and part B)

  This test evaluates speed of processing, visual attention and cognitive flexibility.

  Baseline, immediate after treatment, 4-week follow up

• Change scores of Logical Memory

  It is a subtest of the Wechsler Memory Scale. This test evaluates memory.

  Baseline, immediate after treatment, 4-week follow up

Secondary Outcomes (3)

• Change scores of dual task Timed up-and-go test (manual)

  Baseline, immediate after treatment, 4-week follow up

• Change scores of dual task Timed up-and-go test (cognitive)

  Baseline, immediate after treatment, 4-week follow up

• Change scores of Activities of Daily Living Rating Scale III

  Baseline, immediate after treatment, 4-week follow up

Study Arms (2)

Baduanjin exercise group

EXPERIMENTAL

The intervention group will practice Badunjin in a group which include 6-8 participants and one trained medical staff. The Baduanjin is an ancient Chinese mind-body exercise, which comprised of eight simple movements. The sessions will take place twice a week, 60 minutes per session for a total duration of 12 weeks

Behavioral: Baduanjin exercise program

Control group

ACTIVE COMPARATOR

The control group will receive brisk walking activities. The sessions will take place twice a week, 60 minutes per session for a total duration of 12 weeks

Behavioral: Brisk walking program

Interventions

Baduanjin exercise program BEHAVIORAL

The sessions includes 10-minute warm-up, 40-minute Baduanjin exercise and 10-minute cool down.

Also known as: Eight Silken Movements, Eight Silk Weaving

Baduanjin exercise group

Brisk walking program BEHAVIORAL

The sessions includes 10-minute warm-up, 40-minute brisk walking and 10-minute cool down.

Control group

Eligibility Criteria

• Age: 40 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Having a diagnosis of schizophrenia according to the DSM-5.
• Independent adult aged 40 years or older in the day-care center.
• Having a stable mental status without shift in medication and keep in same dose for at least one month.

You may not qualify if:

• Serious physical conditions that will impede participation, such as cardiovascular disease, musculoskeletal disease or pulmonary system disease.
• Visual or auditory impairment that precludes completion of assessment.
• Acute psychosis requiring hospitalization.
• Presence of severe withdrawal or profound cognitive disability that cause difficulties in following instructions.
• Participating in another clinical trial at the same time.

Sponsors & Collaborators

• Chang Gung Memorial Hospital: lead
• National Taiwan University: collaborator

Study Sites (1)

Chang Gung Memorial Hospital, Kaohsiung Medical Center

Kaohsiung City, 833, Taiwan

Location

MeSH Terms

Conditions

Schizophrenia

Condition Hierarchy (Ancestors)

Schizophrenia Spectrum and Other Psychotic Disorders; Mental Disorders

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 3, 2020
• First Posted: June 12, 2020
• Study Start: April 10, 2021
• Primary Completion: June 30, 2022
• Study Completion: June 30, 2022
• Last Updated: May 30, 2025

Record last verified: 2025-05

Locations

TW (1)