Correlation Between Handgrip Strength and Air Trapping in Patients with Stable Chronic Obstructive Pulmonary Disease

NCT06220851 | Completed

• 1 other identifier: MTU-EC-IM-0-209/65
• Study Type: observational
• Target: 72
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this observational study is to investigate the relationship between handgrip strength and air trapping in patients with chronic obstructive pulmonary disease (COPD). The main question it aims to answer is: • Is handgrip strength correlated with air trapping in COPD patients? Participants will perform handgrip strength test and lung volume measurement.

Conditions

Chronic Obstructive Pulmonary Disease

Keywords

chronic obstructive pulmonary disease; handgrip strength; air trapping; lung volume; correlation

Outcome Measures

Primary Outcomes (1)

• Correlation between handgrip strength and air trapping in COPD patients

  This correlation will be reported as correlation coefficient (R).

  At day 1 of the study

Secondary Outcomes (1)

• The best cutoff value of handgrip strength for predicting air trapping in COPD patients

  At day 1 of the study

Study Arms (1)

COPD

COPD patients aged 40 years or older with a postbronchodilator ratio of forced expiratory volume at one second (FEV1) to forced vital capacity (FVC) \<0.7.

Diagnostic Test: Handgrip strength

Interventions

Handgrip strength DIAGNOSTIC_TEST

Handgrip strength will be measured by 3 efforts.

COPD

Eligibility Criteria

• Age: 40 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

COPD patients aged 40 years or older who are confirmed diagnosis by spirometry (postbronchodilator FEV1/FVC \<0.7) and smoking history 10 pack-years or more.

You may qualify if:

• Age 40 years or older
• Postbronchodilator FEV1/FVC \<0.7
• \>10 pack-year smoking history

You may not qualify if:

• COPD exacerbation within 3 months
• Inability to perform handgrip strength test or lung volume measurement

Sponsors & Collaborators

• Thammasat University: lead

Study Sites (1)

Thammasat University Faculty of Medicine

Pathum Thani, Changwat Pathum Thani, 12120, Thailand

Location

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: January 12, 2024
• First Posted: January 24, 2024
• Study Start: May 1, 2022
• Primary Completion: December 31, 2023
• Study Completion: May 31, 2024
• Last Updated: January 20, 2025

Record last verified: 2025-01

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP

Locations

TH (1)