Resting Energy Expenditure in Palliative Cancer Patients

NCT06206785 | Recruiting

• 1 other identifier: 622545
• Study Type: observational
• Target: 150
• Locations: 1 country
• Sites: 1

Brief Summary

The study purpose is to measure REE by indirect calorimetry and to determine limits of agreement with confidence intervals between measured REE and predictive equations for determination of energy requirements in patients with incurable cancer. Clinical factors associated with hyper- and hypometabolism will be elucidated. Data will be obtained from patient journals in combination with measurements of REE and registration of survival. Data will be collected at one timepoint and survival will be monitored prospectively.

Conditions

Cancer; Cachexia

Outcome Measures

Primary Outcomes (1)

• Measurement of resting energy expenditure (REE) in patients with incurable cancer measured with the COSMED Q-NRG+ Indirect Calorimeter with a Canopy Hood.

  Investigate the agreement between the most used energy expenditure prediction equation (Harris-Benedict calculation for resting energy expenditure based on weight, height and gender) and measured REE (kilocalories/day) by indirect calorimetry in patients with incurable cancer.

  Throughout study completion, approximately 3 years.

Secondary Outcomes (1)

• Clinical factors associated with hyper- and hypometabolism

  Throughout study completion, approximately 3 years.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The population is patients diagnosed with an incurable malignant disease and hospitalized at the cancer clinic, St. Olavs Hospital in the period from september 2023 to june 2026. They have to be 18 years or older and able to provide written informed consent and comply with all study procedures.

You may qualify if:

• A verified diagnosis of an incurable malignant disease
• Hospitalized at the Cancer clinic, St. Olavs Hospital
• ≥ 18 years of age
• Able to provide written informed consent
• Able to comply with all study procedures

You may not qualify if:

• Cognitive impairment
• In need of supplementary oxygen
• Receiving invasive or noninvasive ventilation

Sponsors & Collaborators

• Norwegian University of Science and Technology: lead
• St. Olavs Hospital: collaborator
• UiT The Arctic University of Norway: collaborator

Study Sites (1)

Cancer Clinic, St. Olavs Hospital, Trondheim University Hospital

Trondheim, 7021, Norway

RECRUITING

Related Links

• Current Research Information System in Norway

MeSH Terms

Conditions

Neoplasms; Cachexia

Condition Hierarchy (Ancestors)

Weight Loss; Body Weight Changes; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Thinness

Central Study Contacts

Trude R Balstad, PhD

CONTACT

+4792282665; trude.r.balstad@ntnu.no

Marianne Erichsen, M.Sc.

CONTACT

+4740053267; marianne.erichsen@uit.no

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: OTHER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 14, 2023
• First Posted: January 16, 2024
• Study Start: September 5, 2023
• Primary Completion (Estimated): June 30, 2026
• Study Completion (Estimated): December 31, 2027
• Last Updated: June 6, 2025

Record last verified: 2025-06

Locations

NO (1)