NCT06170099

Brief Summary

The goal of this randomized clinical trial is to compare the effect of LLLT in adolescent patient with class II malocclusion. The main question it aims to answer is: • is there a difference in the amount of distalization between laser and control groups? Participants will received bony supported distal jet. Researchers will compare laser group with control group to see if there is a difference in amount of distalization between groups.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Feb 2020

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 20, 2020

Completed
3.8 years until next milestone

First Submitted

Initial submission to the registry

November 29, 2023

Completed
15 days until next milestone

First Posted

Study publicly available on registry

December 14, 2023

Completed
18 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2024

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2024

Completed
Last Updated

December 14, 2023

Status Verified

December 1, 2023

Enrollment Period

3.9 years

First QC Date

November 29, 2023

Last Update Submit

December 6, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • amount of upper first molar distal movement

    mm/month

    till achievement of class I molar relation, an average of 1 year

Study Arms (2)

Laser group

EXPERIMENTAL
Radiation: low level laser therapyDevice: bonny supported distal jet

control group

ACTIVE COMPARATOR
Device: bonny supported distal jet

Interventions

irradiation with LLLT by the following regimen 0, 3, 7 and 14 from the activation of the bony supported Distal Jet and then every 15 days till completion of distalization

Laser group

distal jet distalizing appliance is supported on two paramedian screw

Laser groupcontrol group

Eligibility Criteria

Age10 Years - 14 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • bilateral Angle's Class II malocclusion minimum of 1/4 cusp discrepancy, normal or low mandibular plane (MP) angle cases and no history of serious medical illness

You may not qualify if:

  • subjects with skeletal Class II with retrusion mandibular profile, vertical growth pattern and steep mandibular plane angle and subjects with shallow or anterior open bite.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Al Azhar dental hospital

Cairo, Nasr City, 002, Egypt

RECRUITING

MeSH Terms

Interventions

Low-Level Light Therapy

Intervention Hierarchy (Ancestors)

Laser TherapyTherapeuticsPhototherapy

Study Officials

  • Rabab HF elhosseini, MSD

    Al-Azhar University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Rabab HF elhosseini, MSD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER GOV
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MSD of Orthodontics

Study Record Dates

First Submitted

November 29, 2023

First Posted

December 14, 2023

Study Start

February 20, 2020

Primary Completion

January 1, 2024

Study Completion

March 1, 2024

Last Updated

December 14, 2023

Record last verified: 2023-12

Locations