Prevalence of Peripheral Vascular Diseases and Presentation in Patients With Autoimmune Diseases

NCT06169865 | Unknown

• 1 other identifier: soh-Med-23-10-03MS
• Study Type: observational
• Target: 300
• Locations: 1 country
• Sites: 1

Brief Summary

Rheumatic autoimmune diseases include conditions such as systemic lupus rheumatoid arthritis systemic sclerosis in which connective tissues are frequently targeted. Autoimmune diseases as a group are among the leading causes of death and morbidity in the industrial world and pose an immense socioeconomic burden despite the considerable accumulative burden of these diseases only a small number of multinational registries for a few selected autoimmune diseases have been devised. Numerous autoimmune inflammatory diseases have been associated with various forms of vasculopathy and increase vascular disease risk such as accelerated atherogenesis and thromboembolic events as digital and acral gangrene secondary Raynaud syndrome arterial aneurysm and different cutaneous ulcer. The etiopathogenesis os increased risk of peripheral vascular diseases and presentation in autoimmune diseases is not entirely clear but multiple contibutors have been explored especially in the context of systemic inflammation and disordered thrombogenesis.

Conditions

Peripheral Vascular Diseases and Presentation in Patient With Autoimmune Diseases

Outcome Measures

Primary Outcomes (1)

• prevalence of peripheral vascular diseases and presentations in patients with autoimmune diseases .

  old and new vascular diseases and presentations in patients with autoimmune diseases

  6 months

Interventions

cross sectional study OTHER

cross sectional study to explore magnitude of peripheral vascular diseases and presentations in patients with autoimmune diseases in sohag society.

Eligibility Criteria

• Sex: all
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

* All ages * Both sexes * Recent or past history of vascular diseases or presentation in any proven autoimmune diseases according to the guidlines.

You may qualify if:

• all ages
• Both sexes
• Recent or past history of vascular diseases or presentation in any proven autoimmune diseases according to the guidlines.

You may not qualify if:

• patients refuse the study
• patients do not have established diagnosis of vascular diseases .
• patients not completely approved to have autoimmune diseases.

Sponsors & Collaborators

• Hossam Adly Mohamed: lead

Study Sites (1)

Sohag university Hospital

Sohag, Egypt

RECRUITING

Related Publications (4)

• Cooper GS, Bynum ML, Somers EC. Recent insights in the epidemiology of autoimmune diseases: improved prevalence estimates and understanding of clustering of diseases. J Autoimmun. 2009 Nov-Dec;33(3-4):197-207. doi: 10.1016/j.jaut.2009.09.008. Epub 2009 Oct 9.

  PMID: 19819109 BACKGROUND

• Zoller B, Li X, Sundquist J, Sundquist K. Autoimmune diseases and venous thromboembolism: a review of the literature. Am J Cardiovasc Dis. 2012;2(3):171-83. Epub 2012 Jul 25.

  PMID: 22937487 BACKGROUND

• Bashal F. Thrombosis in Rheumatological Diseases. 2021 Jan 6. In: Almoallim H, Cheikh M, editors. Skills in Rheumatology [Internet]. Singapore: Springer; 2021. Chapter 12. Available from http://www.ncbi.nlm.nih.gov/books/NBK585742/

  PMID: 36315801 BACKGROUND

• Pyrpasopoulou A, Chatzimichailidou S, Aslanidis S. Vascular disease in systemic lupus erythematosus. Autoimmune Dis. 2012;2012:876456. doi: 10.1155/2012/876456. Epub 2012 Aug 22.

  PMID: 22957213 BACKGROUND

MeSH Terms

Conditions

Peripheral Vascular Diseases

Interventions

Cross-Sectional Studies

Condition Hierarchy (Ancestors)

Vascular Diseases; Cardiovascular Diseases

Intervention Hierarchy (Ancestors)

Epidemiologic Studies; Epidemiologic Study Characteristics; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Central Study Contacts

hosam A Mohamed, resident

CONTACT

01023012244; hosamadly@med.sohag.edu.eg

Ahmed s Abd Alfatah, assistant professor

CONTACT

01096495577

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: resident at vascular surgery department

Study Record Dates

• First Submitted: December 5, 2023
• First Posted: December 14, 2023
• Study Start: September 10, 2023
• Primary Completion: May 10, 2024
• Study Completion: May 10, 2024
• Last Updated: December 14, 2023

Record last verified: 2023-12

Locations

EG (1)