A Study of Gender-specific Impact Factors on Elderly Disability and Cognitive Impairment

NCT06167889 | Completed

• 1 other identifier: YXLL-KY-2023(140)
• Study Type: observational
• Target: 23,640
• Locations: 1 country
• Sites: 1

Brief Summary

Elderly disability and cognitive impairment rates were different between elderly man and woman. Sex-specific risk factors and observed gender differences across the lifespan were associated with different degrees of cognitive and activity of daily living function decline between men and women. However, some of these viewpoint remains controversial. The aim of this study is to explore the gender differences and influencing factors of disability and cognitive impairment among the elderly.

Conditions

Aging

Keywords

Elderly; Disability; Cognitive impairment; Gender-specific

Outcome Measures

Primary Outcomes (2)

• Disability

  We identified disability according to the Katz index. This Katz index includes six activities of daily life: bathing, transferring, dressing, eating, toileting, and continence. Disability was defined as needing help with at least one of the six activities of daily life.

  2002-2023

• Cognitive impairment

  The main outcome was assessed by the Chinese version of the Mini-Mental State Examination (CMMSE).For participants who had never received education, an MMSE score of 17 or less was considered as cognitive impairment; for those who had less than 6 years of education, an MMSE score of 20 or less was considered as cognitive impairment; and for those who had more than 6 years of education, an MMSE score of 24 or less was considered as cognitive impairment. For each level of education, scores above the threshold were considered cognitively normal.

  2002-2023

Study Arms (2)

Retrospective cohort based on Shandong Provincial Qianfoshan Hospital Healthcare Big Data Platform

A retrospective cohort based on Shandong Provincial Qianfoshan Hospital Healthcare Big Data Platform is conducted to collect data and to explore the gender differences and influencing factors of disability and cognitive impairment among the elderly.

Retrospective cohort from CLHLS

The data from the China Longitudinal Healthy Longevity Survey (CLHLS) was used to further validate the results.

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The elderly aged 65 and above in the China Longitudinal Healthy Longevity Survey (CLHLS) database and the elderly with health care neurology visits recorded in Shandong Provincial Qianfoshan Hospital Healthcare Big Data Platform

You may qualify if:

• The elderly aged 65 and above.

You may not qualify if:

• Lack of diagnostic information.
• Missing key influencing factors such as gender and age.
• Hearing or linguistic impairment.
• Comatose patients.

Sponsors & Collaborators

• Fang Tang: lead

Study Sites (1)

The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital

Jinan, Shandong, 250014, China

Location

MeSH Terms

Conditions

Cognitive Dysfunction

Condition Hierarchy (Ancestors)

Cognition Disorders; Neurocognitive Disorders; Mental Disorders

Study Officials

• Fang Tang, Doctor

  The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Doctor

Study Record Dates

• First Submitted: December 4, 2023
• First Posted: December 13, 2023
• Study Start: January 1, 2009
• Primary Completion: October 31, 2023
• Study Completion: October 31, 2023
• Last Updated: December 13, 2023

Record last verified: 2023-12

Locations

CN (1)