Immune Status of Elderly Population Admitted in an Acute Geriatric Unit

NCT00823589 | Completed

• 1 other identifier: 2008 -21
• Study Type: interventional
• Target: 78
• Locations: 1 country
• Sites: 1

Brief Summary

Ageing is associated with vulnerability against infections leading to increased morbidity with risk of death. Innate and adaptive immunities are altered with ageing responsible of deficits in immune response against pathogens and after vaccination, and favouring the elderly vulnerability against a new pathogen with increased bacterial, viral, and fungal infections. If immunity has been widely studied in immunosenescence, there are few prospective, comparative studies with elderly ill patients. Moreover among these studies, pathologies are not well defined. The main objective of our project is to compare the immune state of elderly hospitalised subjects in an acute geriatric unit to the immune state of elderly healthy subjects selected with strict criteria, in order to precise the impact of polypathology and of various pathologies on immunity state.

Conditions

Aging

Keywords

ELDERLY POPULATION

Outcome Measures

Primary Outcomes (1)

• compare the immune state of elderly hospitalised subjects in an acute geriatric unit to the immune state of elderly healthy subjects

  2 years

Study Arms (2)

pathological group

EXPERIMENTAL

pathological group

Other: Blood test and clinical test

healthy aged

EXPERIMENTAL

healthy aged

Other: Blood test and clinical test

Interventions

Blood test and clinical test OTHER

Blood test and clinical test

healthy aged; pathological group

Eligibility Criteria

• Age: 75 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Older Adult (65+)

You may qualify if:

• Subject of 75 or more years old, female or male
• Subject admitted in the service of short stay gériatrique of the hospital Holy Marguerite, whatever is the motive for admittance
• Subject not being under supervision(guardianship), nor guardianship
• Subject benefiting from a benefit system
• Subject having given its assent of participation or for which the reliable person gave her assent in the case of vulnerable person

You may not qualify if:

• Subject of less than 75 years old
• Subject refusing to participate in the study or for whom(which) the reliable person refuses the participation of the subject

Sponsors & Collaborators

• Assistance Publique Hopitaux De Marseille: lead

Study Sites (1)

HOPITAL DE SAINTE MARGUERITE Service de Gériatrie Sud

Marseille, Paca, France

Location

MeSH Terms

Interventions

Hematologic Tests

Intervention Hierarchy (Ancestors)

Clinical Laboratory Techniques; Diagnostic Techniques and Procedures; Diagnosis; Investigative Techniques

Study Officials

• ELODIE CRETEL

  Assistance Publique Hopitaux De Marseille

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 14, 2009
• First Posted: January 15, 2009
• Study Start: January 1, 2009
• Primary Completion: February 1, 2012
• Study Completion: February 1, 2012
• Last Updated: February 25, 2014

Record last verified: 2014-02

Locations

FR (1)