Preoperative Ultrasonographic Evaluation of Caval Aorta Diameter Index

NCT06155461 | Unknown DMC

• 1 other identifier: Anaesth._0319/2023Med.Research
• Study Type: observational
• Target: 105
• Locations: 1 country
• Sites: 1

Brief Summary

General anesthesia is frequently used in daily clinical practice. Elderly patients often require a higher level of care than younger patients during the perioperative period, with higher health care costs. Strategies to optimize anesthesia care to reduce complications and improve outcomes in elderly surgical patients will also be of great value to the individual patients and society.

Conditions

Hypotension; Geriatric Patients; Anesthesia

Outcome Measures

Primary Outcomes (1)

• Evaluate the predictive value of pre-induction IVC

  Area under receiver operating characteristic curves (AUROC) of the preoperative IVCCI inprediction of post-induction hypotension

  5 minutes

Secondary Outcomes (2)

• Incidence of post-induction hypotension

  5 minutes

• Correlation between each of IVC collapsibility index with the percentage of the maximum decrease in mean arterial pressure after induction of anesthesia

  5 minutes

Interventions

Preoperative Ultrasonographic Evaluation of Caval Aorta Diameter Index PROCEDURE

to evaluate the ability of preoperative ultrasound measurements of IVC to aorta diameter index and the inferior vena cava collapsibility index (IVCCI) for predicting post induction hypotension after general anesthesia in geriatric patients.

Eligibility Criteria

• Age: 60 Years - 85 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients undergoing elective surgery under general anesthesia, ASA I, II

You may qualify if:

• Adult patients ( 60 - 85 ) years old of both sexes with American Society of Anesthesiologists (ASA) physical status I-II and scheduled for elective surgeries under general anesthesia.

You may not qualify if:

• Refusal to join the study.
• Mental and psychiatric disorders (un co-operative patients).
• Emergency operations
• ASA physical status \> II
• Dyspnea, respiratory distress, un-compensated respiratory disease (generalized wheezes, defective functional capacity, peripheral O2 saturation less than 90% on room air )
• patients with uncontrolled hypertension, Systolic blood pressure ≥ 180 mmHg
• IVC non visualized
• Patients with increased intra-abdominal pressure (intra-abdominal mass compressing IVC).
• anticipated or accidental discovered difficult airway
• patients taking angiotensin converting enzyme inhibitors or angiotensin receptors blockers, documented heart failure, elevated pulmonary arterial pressure \> 40 mmHg, significant valvular heart disease, significant carotid stenosis, peripheral vascular diseases, unstable angina or cardiac ejection fraction less than 40%, implanted pacemaker or cardioversion , known cases of abdominal aortic abnormality as aneurysm or previous operations.

Sponsors & Collaborators

• Egymedicalpedia: lead

Study Sites (1)

Al-Azhar University hospitals

Cairo, Egypt

RECRUITING

MeSH Terms

Conditions

Hypotension

Condition Hierarchy (Ancestors)

Vascular Diseases; Cardiovascular Diseases

Study Officials

• Ahmed Saied, Professor

  Al-Azhar University, Faculty of medicine for boys

  STUDY CHAIR

Central Study Contacts

Mohammad Al-Bahar, M.D

CONTACT

01116723370; dr.ms.bahar3@gmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: INDUSTRY
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 19, 2023
• First Posted: December 4, 2023
• Study Start: April 1, 2023
• Primary Completion: April 1, 2024
• Study Completion: April 15, 2024
• Last Updated: December 4, 2023

Record last verified: 2023-11

Locations

EG (1)