Prediction of Hypotension During Induction of General Anesthesia

NCT06078228 | Unknown DMC

• 1 other identifier: FMASU MD205/2023
• Study Type: observational
• Target: 70
• Locations: 1 country
• Sites: 1

Brief Summary

Post induction hypotension is closely related to postoperative complications. Patients are at high risk of hypotension due to preexisting hypovolemia and the vasodilatory effects of induction agents. Ultrasonographic measurement of the Carotid artery corrected flow time and internal jugular vein collapsibility index may predict post induction hypotension.

Conditions

Anesthesia

Outcome Measures

Primary Outcomes (1)

• the predictive value of the carotid Ftc for prediction of hypotension.

  to investigate the reliability of preanesthetic ultrasound measurements of the carotid artery FTc and the internal jugular vein collapsibility index in predicting hypotension during the induction of general anesthesia

  one year

Interventions

Propofol - Fentanyl- Atracurium DRUG

investigate the reliability of preanesthetic ultrasound measurements of the carotid artery FTc and the internal jugular vein collapsibility index in predicting hypotension during the induction of general anesthesia.

Also known as: Atropine

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Adult patient undergoing elective surgeries.

You may qualify if:

• Patients of American Society of Anesthesiologists (ASA) physical status I to II of both genders.
• Aged 18-65 years. 3- Elective surgeries under general anesthesia. 4- BMI less than 40.

You may not qualify if:

• Patients with
• Renal diseases.
• Hepatic diseases.
• ASA scores of 3-4.
• The presence of a left ventricular ejection fraction less than 50%.
• Age under 18 years old.
• Patient refusal.
• Coronary heart disease.
• Cardiac disease including cardiomyopathy and mild to severe valve disease.
• Pulmonary hypertension.
• Peripheral arterial disease.
• Preoperative cervical vascular ultrasound abnormalities including plaque, stenosis and anatomical variation.
• Any previous neck surgery or trauma.

Sponsors & Collaborators

• Ain Shams University: lead

Study Sites (1)

Ain Shams University

Cairo, Abbassia, 7154411, Egypt

Location

MeSH Terms

Interventions

Atropine

Intervention Hierarchy (Ancestors)

Atropine Derivatives; Tropanes; Azabicyclo Compounds; Aza Compounds; Organic Chemicals; Belladonna Alkaloids; Solanaceous Alkaloids; Alkaloids; Heterocyclic Compounds; Bridged Bicyclo Compounds, Heterocyclic; Heterocyclic Compounds, Bridged-Ring

Study Officials

• Marina George, MD candidate

  Ain Shams University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Day
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 5, 2023
• First Posted: October 11, 2023
• Study Start: September 24, 2023
• Primary Completion: August 17, 2024
• Study Completion: August 17, 2024
• Last Updated: August 5, 2024

Record last verified: 2023-09

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)