Hospital- and Home-Based Structured Pulmonary Rehabilitation in Recently Admitted COPD Patients: A Quasi-Experimental Study at Assiut University

NCT07197229 | Not Yet Recruiting

• 1 other identifier: Combined Pulmonary Rehabilitat
• Study Type: interventional
• Target: 70
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study evaluates the effect of a structured three-month pulmonary rehabilitation (PR) program, delivered both in-hospital and at home, on exercise capacity, respiratory symptoms, and functional status in stable COPD patients.

Conditions

COPD

Keywords

COPD

Outcome Measures

Primary Outcomes (1)

• Six-Minute Walk Test (6MWT)

  Measures the distance (in meters) a patient can walk in six minutes as a marker of exercise capacity and functional endurance.

  12 weeks

Study Arms (1)

patients diagnosed with moderate-to-severe COPD (confirmed by spirometry) who are clinically stable

EXPERIMENTAL

Participants undergo a 12-week structured PR program including both hospital-based sessions (education, structured exercise, nutrition counseling, smoking cessation) and home-based exercises (daily walking, strength training progression).

Behavioral: Pulmonary Rehabilitation

Interventions

Pulmonary Rehabilitation BEHAVIORAL

A tailored pulmonary rehabilitation program combining hospital-based and home-based components over 12 weeksParticipants undergo a 12-week structured PR program including both hospital-based sessions (education, structured exercise, nutrition counseling, smoking cessation) and home-based exercises (daily walking, strength training progression

patients diagnosed with moderate-to-severe COPD (confirmed by spirometry) who are clinically stable

Eligibility Criteria

• Age: 40 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Stable COPD patients diagnosed based on spirometry (post-bronchodilator FEV1/FVC \<70%)
• Age \> 40 years
• Moderate to severe COPD stage
• Able and willing to participate in rehabilitation program

You may not qualify if:

• Age \< 40 years
• Current acute COPD exacerbation at enrollment
• Significant comorbid conditions limiting participation (e.g., uncontrolled diabetes mellitus, uncontrolled hypertension, left-sided heart failure, renal failure, liver cell failure)
• Neuromuscular diseases, severe cognitive impairment, or psychiatric disturbance
• Pregnant patients
• Unwilling to participate in the rehabilitation program

Sponsors & Collaborators

• Assiut University: lead

Related Publications (1)

• Arnold MT, Dolezal BA, Cooper CB. Pulmonary Rehabilitation for Chronic Obstructive Pulmonary Disease: Highly Effective but Often Overlooked. Tuberc Respir Dis (Seoul). 2020 Oct;83(4):257-267. doi: 10.4046/trd.2020.0064. Epub 2020 Aug 10.

  PMID: 32773722 BACKGROUND

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: resident at the chest department

Model Details: ince this is a quasi-experimental single-arm study, there is only one intervention group the Pulmonary Rehabilitation Group: Participants undergo a 12-week structured PR program including both hospital-based sessions (education, structured exercise, nutrition counseling, smoking cessation) and home-based exercises (daily walking, strength training progression).

Study Record Dates

• First Submitted: September 20, 2025
• First Posted: September 29, 2025
• Study Start: April 30, 2026
• Primary Completion (Estimated): October 30, 2027
• Study Completion (Estimated): December 30, 2027
• Last Updated: September 29, 2025

Record last verified: 2025-09

Data Sharing

• IPD Sharing: Will not share