Effect of Exercise-education Program PERMANENTO in Late Life

NCT06133894 | Completed

• 1 other identifier: NU22-09-00447
• Study Type: interventional
• Target: 90
• Locations: 1 country
• Sites: 1

Brief Summary

The general aim of the present study is to create and empirically evaluate (RCT trial) an online education and exercise program (called PERMANENTO) to help older adults to understand the wider consequences of being active and offer them easy to follow exercise program inspired by developmental kinesiology.

Conditions

Frailty; Sarcopenia

Keywords

prevention; older adults; functional status; frailty; sarcopenia; exercise; on-line program; sustainability

Outcome Measures

Primary Outcomes (6)

• Timed up-and go test

  Performance-based measure of functional mobility and balance in older adults.The test requires the participant to rise from a chair, walk 3.0 m at a comfortable pace to a mark placed on the floor, turn around at the 3.0 m mark, walk back to the starting point, and return to sitting in the chair. The test's score is the time it takes the subject takes to complete the test. Lower score is better result.

  Within a week prior the intervention and within a week after the intervention

• Limits of stability on NeuroCom

  The Limits of Stability (LOS) test quantifies the maximum distance participant can lean own body (i.e. intentionally weight shift) in a given direction without losing balance, stepping, or reaching for assistance as would be required for function and gait. The scores for each parameter and movement direction are represented by a numeric value. Higher score is better result.

  Within a week prior the intervention and within a week after the intervention

• The Sensory Organization Test on NeuroCom

  The Sensory Organization Test (SOT) objectively identifies abnormalities in the patient's use of the three sensory systems that contribute to postural control: somatosensory, visual, and vestibular. The scores summarize the overall function of the three systems and the ability to resolve conflicting sensory inputs. Scores range from 0 to 100 (higher score, better result). Composite score identifies the presence of a balance control problem. Scores range from 0 to 100 (higher score, better result).

  Within a week prior the intervention and within a week after the intervention

• Body composition on InBody 720

  The multifrequency body composition analyser InBody720 analyses body composition via the method of bioelectrical impedance (DSM-BIA) for every part of the body using 6 different frequencies (1kHz, 5kHz, 50kHz, 250kHz, 500kHz, 1000kHz) in each one of the five parts of the body with the quadrupole 8-point tactile system. It provides wide range of outcomes (main focus on: Body fat mass - lower score, better result, Skeletal muscle mass - higher score, better result, Visceral Fat - lower score, better result).

  Within a week prior the intervention and within a week after the intervention

• Handgrip strength on dynanometr

  Handgrip strength test is to measure the maximum isometric strength of the hand and forearm muscles. Participant is instructed to squeezes the dynamometer with maximum isometric effort, which is maintained for about 5 seconds. No other body movement is allowed. Higher score, better result.

  Within a week prior the intervention and within a week after the intervention

• Perceived functional fitness and health status

  Measured by questions "In general, would you say your health is poor, fair, good, very good, or excellent?" and "In general, would you say your functional fitness is poor, fair, good, very good, or excellent?". Score are represented on 5-point scale: (1) Excellent, 2) Very Good, 3) Good, 4) Fair, or 5) Poor). Lower score, better result.

  Within a week prior the intervention and within a week after the intervention

Secondary Outcomes (1)

• Long-term sustainability

  6 and 12 months after the end of the intervention

Study Arms (2)

Experimental group

EXPERIMENTAL

The experimental group was educated and instructed and agaged in a 12-week exercise program - 15 minutes 6 times per week of complex daily routines delivered via on-line platform.

Behavioral: Exercise program PERMANENTO inspired by developmental kinesiology

Contol group

NO INTERVENTION

The control group continued in regular daily activities and was offered the same intervention as the experimental group after the research trial.

Interventions

Exercise program PERMANENTO inspired by developmental kinesiology BEHAVIORAL

The intervention is based on activation of reflexive movement patterns which ensures the original reflexive control of strength, mobility and stability. After birth, we cannot control our body movements - they are reflexes "hard-wired" into our brains and vitally important for proper development of our body (muscular system, vestibular system, sensory system, cardiovascular system or digestive system) as well as our brain and nervous systems. During early childhood, everything becomes integrated and works perfectly according to the original design. But this design is slowly abandoned due to for example sedentary lifestyle and replaced by compensatory movement patterns that are making us weaker and defective with all the consequences that are becoming more severe as we age. The aim is restore the original design and improve posture and other crucial components of functional fitness and move better and more.

Experimental group

Eligibility Criteria

• Age: 70 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Older Adult (65+)

You may qualify if:

• permanent residency in Prague
• being at least 70 years of age or older
• living independently at home

You may not qualify if:

• significant mobility limitation
• any health condition preventing from physical activity

Sponsors & Collaborators

• Charles University, Czech Republic: lead

Study Sites (1)

Centre of Expertise oi Longevity and Long-term Care

Prague, 182 00, Czechia

Location

MeSH Terms

Conditions

Frailty; Sarcopenia; Motor Activity

Condition Hierarchy (Ancestors)

Pathologic Processes; Pathological Conditions, Signs and Symptoms; Muscular Atrophy; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Atrophy; Pathological Conditions, Anatomical; Signs and Symptoms; Behavior

Study Officials

• Katerina Machacova

  Centre of Expertise in Longevity and Long-term care, Faculty of Humanities, Charles University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Masking Details: Single blinded study
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Model Details: Randomized controlled trial of volunteers over 70 years of age

Study Record Dates

• First Submitted: November 6, 2023
• First Posted: November 18, 2023
• Study Start: February 13, 2023
• Primary Completion: May 15, 2023
• Study Completion: June 15, 2023
• Last Updated: November 18, 2023

Record last verified: 2023-11

Data Sharing

• IPD Sharing: Will not share

Locations

CZ (1)